Metastatic aortic body tumour causing neck pain in a dog

Callanan, John J.; McNeil, P. E.; Anderson, Thomas; Laird, Helen M.

doi:10.1111/j.1748-5827.1991.tb00873.x

Cited by 9 publications

(9 citation statements)

References 7 publications

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“…Tumours of the chemoreceptor organs are termed chemodectomas and occur most commonly in dogs, arising mainly from the aortic body (Owen et al, 1996); the tumours are generally benign but may metastasize (Callanan et al, 1991). Occasional aortic body tumours have been reported in cats (Tillson et al, 1994) and horses (de Barros and dos Santos, 1983) principally in the aortic and carotid bodies, and Levy et al (1990) mention a chemodectoma arising in the ciliary ganglion in a horse.…”

Section: Introductionmentioning

confidence: 99%

Immunohistochemical Characteristics of Canine Aortic and Carotid Body Tumours

Brown

Rêma

Gärtner

2003

Journal of Veterinary Medicine Series A

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In an immunohistochemical study of 25 canine chemodectomas, 17 tumours were stained with antisera to neurone specific enolase and the same number were stained for synaptophysin; a single tumour was stained for S100. Staining for Ki-67 occurred in 18 cases; the Ki-67-labelling index and the intensity of immunostaining was increased in more pleomorphic and malignant tumours, as assessed on histological grounds. Immunohistochemistry did not aid in recognition of less well-differentiated tumours.

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Section: Introductionmentioning

confidence: 99%

Immunohistochemical Characteristics of Canine Aortic and Carotid Body Tumours

Brown

Rêma

Gärtner

2003

Journal of Veterinary Medicine Series A

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“…6 The true proportion of dogs with metastatic as compared with primary cardiac tumors is unknown, but reports describing primary cardiac tumors in dogs 4,[7][8][9][10][11] are more numerous than those describing metastatic disease. 16,17,22,40,[49][50][51][52][53][54][55][56] The most common histologic types of cardiac tumors in dogs are different from those in humans. About 75% of primary cardiac tumors in humans are benign and nearly 50% of these are myxomas (usually involving the left atrium).…”

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confidence: 99%

“…2,4,8,33 Aortic body tumors (ABT) also have been reported relatively frequently in dogs. 7,22,25,31,32,34,37,42,43,45,47,49,57,[62][63][64][65][66][67][68][69] ABT are tumors of chemoreceptor tissue located at the aortic root or heart base. Only sporadic cases of cardiac myxoma have been reported in dogs.…”

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confidence: 99%

Cardiac Tumors in Dogs: 1982–1995

Ware

Hopper

1999

Veterinary Internal Medicne

205

185

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A Veterinary Medical Database search from 1982 to 1995 identified 1,383 dogs with tumors of the heart from a total population of 729,265 dogs (0.19% incidence). Hemangiosarcoma (HSA) was the most common cardiac tumor identified. In the subset of dogs with specific histologic diagnoses, the number with HSA was almost 10-fold that of the 2nd most common tumor, aortic body tumor. Primary heart tumors were more common than cardiac metastases. When biologic behavior was noted, most heart tumors were classified as malignant. Cardiac tumors (excluding lymphoma) occurred most often in dogs between the ages of 7 and 15 years. In very old dogs (>15 years), the frequency of cardiac tumors was the same or lower than that of the youngest age group. Tumors occurred with similar frequency in males and females, but the relative risk for spayed females was >4 times that for intact females. For HSA, spayed females had >5 times greater relative risk than did intact females. The risk for castrated males was slightly greater than that for intact males, which had 2.4 times the relative risk of intact females. Thus, neutering appeared to increase the risk of cardiac tumor in both sexes. Intact females were least likely to develop a cardiac tumor, whereas spayed females were most likely to develop a tumor. Twelve breeds had greater than average risk of developing a cardiac tumor, whereas 17 had lower risk.

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“…Chemodectomas are usually benign; however, carcinomas have been reported. Metastases occur in about 30% of cases, and often involve vertebrae, lung, regional lymph nodes, liver, pancreas and kidney 2,7 . The main threat posed by a chemodectoma is through its anatomical location at the base of the heart, which can result in compromised cardiac function and blood flow, and lead to congestive heart failure and reduced cardiac output.…”

Section: Discussionmentioning

confidence: 99%