Summary
Bruggimann L, Annoni J-M. [Management of anxious disorders in neurological diseases.] Schweiz Arch Neurol Psychiatr 2004;155:407-13.Neuropsychiatric sequelae are a significant cause of morbidity in neurological patients. Current studies suggest that anxiety is frequent (about 20 to 30%) in all these conditions. Neurobiological, environmental and dispositional factors may be implicated in the development of anxiety suggesting that several ways of intervention are worth to be considered, e.g. pharmacological, socio-educative or psychotherapeutic interventions. Anxiety disorders following medical problems are often undiagnosed or inadequately treated. This may reflect difficulties with the diagnosis of affective disorders among people with neurological affections, but may also reflect uncertainty about the effectiveness of interventions in this setting.This review addresses the emergence of anxiety disorders in three classical neurological conditions, namely stroke, dementia and multiple sclerosis. Prevalence of anxiety, characteristics, contributing factors and associated cerebral lesions are discussed for each of these neurological conditions. Existing research literature on psychological and psychotherapeutic interventions to manage anxiety is then reported. Pharmacological therapy is not considered.Any psychotherapeutic treatment is necessarily limited by the cognitive and the behavioural disorders characterising each neurological condition. Consequently, usefulness of the intervention should always be evaluated in the context of a specific disease. The paucity of research and the methodological limitations in existing studies prevent a conclusion as any psychological intervention has empirical support for its effectiveness. However, different approaches seem to be worthy of further investigation.Cognitive behaviour therapy (CBT) is an appropriate treatment for some anxious or depressed patients with cerebrovascular disease or multiple sclerosis. This approach includes identification and modification of unhelpful thoughts and beliefs, activity scheduling and graded task assignment. There are very few controlled studies, but they suggest that this kind of therapy may have the same effect as pharmacological treatments. Mood, anxiety, adherence to medications and appraisal of self-control are susceptible to improvement after cognitive behaviour therapy. Interesting results may also be obtained using educative programmes. Preliminary results indicate that a brief intervention designed to change patients' illness perceptions can result in improved functional outcome after severe medical affection. Combined with cognitive behaviour therapy, such an approach is promising. Therapy has to be adapted particularly in dementia, where cognitive and behavioural disorders are the most pronounced. Group interventions based on verbal or non verbal (e.g. painting) interactions reveal interesting therapeutic effects such as the dissolution of anxiety into the group, the acceptance of aging or the reaffirmation of oneself ...