Frequency of Depression After Stroke

Abstract

Background and Purpose-Although depression is an important sequelae of stroke, there is uncertainty regarding its frequency and outcome. Methods-We undertook a systematic review of all published nonexperimental studies (to June 2004) with prospective consecutive patient recruitment and quantification of depressive symptoms/illness after stroke. Results-Data were available from 51 studies (reported in 96 publications) conducted between 1977 and 2002. Although frequencies varied considerably across studies, the pooled estimate was 33% (95% confidence interval, 29% to 36%) of all stroke survivors experiencing depression. Differences in case mix and method of mood assessment could explain some of the variation in estimates across studies. The data also suggest that depression resolves spontaneously within several months of onset in the majority of stroke survivors, with few receiving any specific antidepressant therapy or active management. Conclusions-Depression is common among stroke patients, with the risks of occurrence being similar for the early, medium, and late stages of stroke recovery. There is a pressing need for further research to improve clinical practice in this area of stroke care.

The association between mean platelet volume levels and poststroke depression

“…In this study, 32.4% of patients developed PSD at 1 month after stroke, the prevalence is similar to previous researches (Allan et al, 2013; Hackett & Pickles, 2014; Hackett, Yapa, Parag, & Anderson, 2005). We found that female gender was significantly correlated with PSD, which was consistent with earlier findings (Guiraud et al, 2016; Mazure, Weinberger, Pittman, Sibon, & Swendsen, 2014; Zhang, Zhao, Fang, Wang, & Zhou, 2017).…”

Hidden Dysfunctioning in Subacute Stroke

“…18,29 The association between depression and CDF is consistent with prior studies, 30,31 because depression is common after stroke and has been directly related to cognitive impairment. [32][33][34] It has been argued that CDF could reflect depression or fatigue. 35 In our study, depression and "fatigue" as a Beck Depression Inventory item were associated with CDF in bivariate analysis.…”

Vascular depression: myth or reality?

“…Two recent systematic reviews showed that up to one in three people develop clinically significant depressive symptoms after a stroke (Hackett et al, 2005) or myocardial infarction (Thombs et al, 2006). These findings are consistent with cardiovascular disease having a role in predisposing, precipitating and perpetuating the symptoms of depression in later life.…”

“…Numerous studies have been carried out over the past 10 years on the epidemiology of depression associated with cerebrovascular disease (e.g. Hackett et al, 2005), its clinical features (e.g. Naarding et al, 2007), pathogenesis (e.g.…”