Anxiety and depression are associated with unhealthy lifestyle in patients at risk of cardiovascular disease

Bonnet, Fabrice; Irving, Kate; Terra, Jean‐Louis; Nony, Patrice; Berthezéne, F; Moulin, Philippe

doi:10.1016/j.atherosclerosis.2004.08.035

Cited by 362 publications

(286 citation statements)

References 19 publications

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“…Nearly one in five patients with bipolar disorder have metabolic syndrome and from 16% up to 36% have components of it [65]. Lipid dysregulation can be associated with genetics, comorbidity, psychiatric psychopathology, lifestyle, diet, physical activity, alcohol abuse, smoking and pharmacotherapy [64,[66][67][68][69][70][71].…”

Section: Affective Disordersmentioning

confidence: 99%

Application of fatty acid and lipid measurements in neuropsychiatry

Grela

Rachel

Cole

et al. 2016

Clinical Chemistry and Laboratory Medicine (CCLM)

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Abstract:The importance of lipids in the understanding of disease states is constantly increasing. Whilst the link between metabolic disorders and lipids seems to be clear, interpreting lipid regulation in the context of neuropsychiatric disorders is a new approach. Mental disorders account for almost 15% of the total global disease burden with Alzheimer's disease, depression or schizophrenia being amongst the most widespread mental disorders in the general population. For this reason rapid and early diagnosis is crucial and finding the right biomarkers is of great importance. Lipids appear to be essential in learning the aetiopathology of neuropsychiatric diseases as well as in biomarker research as they are most abundantly present in the brain. This study discusses recent findings in neuropsychiatry in the context of lipid analysis.

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Section: Affective Disordersmentioning

confidence: 99%

Application of fatty acid and lipid measurements in neuropsychiatry

Grela

Rachel

Cole

et al. 2016

Clinical Chemistry and Laboratory Medicine (CCLM)

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show abstract

“…Medication nonadherence may also be a marker of other unhealthy behaviors that increase risk of cardiac events in depressed patients. 26,30 …”

Section: How Might Depression Lead To Cardiac Events?mentioning

confidence: 99%

Depression and Cardiovascular Disease

Whooley¹

2006

JAMA

218

163

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Major depressive disorder is a risk factor for the development of incident coronary heart disease events in healthy patients and for adverse cardiovascular outcomes in patients with established heart disease. Depression is present in 1 of 5 outpatients with coronary heart disease and in 1 of 3 outpatients with congestive heart failure, yet the majority of cases are not recognized or appropriately treated. It is not known whether treating depression improves cardiovascular outcomes, but antidepressant treatment with selective serotonin reuptake inhibitors is generally safe, alleviates depression, and improves quality of life. This article evaluates the importance of major depression in patients with cardiovascular disease, and provides practical guidance for identifying and treating this disorder. CASE PRESENTATIONA 58-year-old man with a history of coronary heart disease (CHD), type 2 diabetes mellitus, hypertension, smoking, and alcohol dependence presented for routine medical care. He had initially sought medical attention for exertional angina 5 years previously, at which time he underwent exercise treadmill testing with thallium that was positive for reversible perfusion defects in the anterior, septal, and inferior walls. Subsequent coronary angiography revealed diffuse heavy calcifications in the left anterior descending artery with a moderate lesion prior to the first diagonal. Several major septal perforators had significant lesions at their origins. In the dominant right coronary artery, there were diffuse calcifications but no significant lesions. The left circumflex and large ramus intermedius were free of discrete lesions. Left ventricular function was normal.The patient underwent single-vessel (left internal mammary artery to left anterior descending artery) coronary artery bypass grafting (CABG) surgery. He was prescribed atenolol 100 mg/ d, lisinopril 40 mg/d, lovastatin 80 mg/d, aspirin 325 mg/d, metformin 850 mg 3 times a day, and glipizide 10 mg 2 times a day. Despite being nonadherent to his prescribed medications, he remained stable for 5 years, but then one day, while doing household chores, he suddenly developed chest pressure, shortness of breath, and diaphoresis that lasted 12 hours. On admission to the hospital his troponin I was elevated and peaked at 0.7 ng/mL (normal, <0.05 ng/mL), consistent with a myocardial infarction (MI). His electrocardiogram had not changed.

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“…The first pathway is via behavioral mechanisms. Emotional stress was found to be associated with unhealthy lifestyle behaviors, i.e., inadequate eating behaviors in terms of quality and quantity of food, low exercise levels, smoking and alcohol abuse (Bonnet et al, 2005;Rod et al, 2009). All these factors are well-known risk factors for the development of type 2 diabetes.…”

Section: Psychological Stress Predisposing To Dmmentioning

confidence: 99%

The Bidirectional Relationship Between Psychiatry and Type 2 Diabetes Mellitus

Rabie¹

2011

Topics in the Prevention, Treatment and Complications of Type 2 Diabetes

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Anxiety and depression are associated with unhealthy lifestyle in patients at risk of cardiovascular disease

Cited by 362 publications

References 19 publications

Application of fatty acid and lipid measurements in neuropsychiatry

Application of fatty acid and lipid measurements in neuropsychiatry

Depression and Cardiovascular Disease

The Bidirectional Relationship Between Psychiatry and Type 2 Diabetes Mellitus

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