Antiviral effects of a synthetic Aluminium-Magnesium Silicate, on Avian Influenza Virus

Abstract

Effects a synthetic Aluminium-Magnesium Silicate [AMS] has on Avian Influenza Virus (AIV) were tested. Equal amounts of AIV samples and of the AMS were mixed, kept one hour at room temperature before centrifuging. The supernatants were remeasured and tested for, viral titre, Mean Death Time (MDT) and Mortality Rate of chicken Embryos (EMR). Volumes of the viral samples reduced at rate of 23.4% ± 5.48%. Viral titres reduced significantly (P < 0.01) from HA, 73 ± 32.72 to 1.4 ± 0.43. Also, EMR of infected chicken embryos reduced from 100% to 65%, while MDT of those that died,increased significantly (P < 0.01) from 76 ± 4.38 to 136 ±18.93 hours. When incubation with AMS was repeated on portions of an AIV sample, MDT increased from 64 to 104 hours with the portion incubated once. AIV portions on which incubation with AMS was repeated could not kill chicken embryos

Aluminum-Magnesium Silicate enhances release of virions of cultured <i>Fowl Pox Virus</i> and inhibits the virus

“…This result agrees with earlier results got with use of the AMS on Peste des Petits Ruminants Virus [24], Infectious Bursa Disease virus [16], Canine parvovirus [17], Egg Drop Syndrome Virus [25], Newcastle disease Virus [18] and Avian Influenza virus [26]. Chenicoff and Venkatachrisnan [8] reported that Aluminum-Magnesium Silicate molecules poss both positive and negative electrically charged ends.…”

Monitoring of aquatic birds and surveillance of avian influenza and Newcastle disease of waterfowls at the National Park of Urmia Lake

“…Therefore, the following measures should be provided. (1) Some practical solutions to reduce shedding of the viruses by treating the wild birds via using antiviral drugs (Ezeibe et al, 2011;Ezeibe et al, 2012) during migration time.…”

“…Therefore, the following measures should be provided. (1) Some practical solutions to reduce shedding of the viruses by treating the wild birds via using antiviral drugs (Ezeibe et al., 2011; Ezeibe et al., 2012) during migration time. (2) Establishment of a water birds' census centre in the region to provide all the necessary information on water birds and the passive surveillances.…”

Assessment of Antiretroviral Effects of a Synthetic Aluminum-magnesium Silicate

“…Studies have shown that the AMS has antiviral effects against all seven viruses so far tested [18][19][20][21][22][23][24]. Since net electrical charge of HIV is positive, while those on AMS platelets are negative [10,12], AMS may have antiretroviral effects.…”