“…As a result, renal function (serum creatinine and urine protein) must be monitored 48 h before each dose of cidofovir, and dose adjustments must be made if renal function changes 20,58‐60 . In general, brincidofovir, a prodrug of cidofovir, has a better safety profile than cidofovir, with no reports of serious renal toxicity or other adverse events in the treatment of CMV and Mpox infection when compared to cidofovir 61,62 …”