Antiurolithiatic Activity of Ethanolic Extract of Taxillus Tomentosus Plant on Ethylene Glycol and Ammonium Chloride Induced Urolithiasis in Wistar Rats
Abstract:The present study investigates the potential of antiurolithiatic activity of ethanolic extract of Taxillus tomentosus plant (EETT). Urolithiasis was induced by feeding the 0.75% of Ethylene glycol (EG) and 2% of Ammonium chloride (AC) in drinking water along with the normal feed in male wistar rats and then the anti-urolithiatic activity of EETT was evaluated. Acute toxicity study was conducted by LD50 cutoff dose of 2000mg/kg body weight (BW), indicates that the drug to be much safer and 1/10 th (200mg/kg BW)… Show more
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