Antitumor activity and metal complexes of the first transition series. Trans-bis(salicylaldoximato)copper(II) and related copper(II) complexes, a novel group of potential antitumor agents

Synthesis, Characterization and Antimicrobial Activity of Potassium Hydro(benzoyl)(phthalyl)borate and Its Cobalt(II), Nickel(II), and Copper(II) Complexes

“…The spectra of the cobalt(II) complex consist of transition bands at 520 and 565 nm which are assigned to the transition 4 T 1g → 4 T 1g (P), 682 nm which is assigned to the transition 4 T 1g → 2 T 1g , 2 T 1g , and 739 and 824 nm which are assigned to the transition 4 T 1g → 4 T 2g . These transition bands establish an octahedral geometry around the cobalt(II) ion.…”

“…2 Literature reports have shown that, organoborates like poly(pyrazolyl)-borates, have unique selectivity for metal ions due to different steric factors from the conventional ligands. 3 Organoborate ligands have found important application as biocides 4,5 on account of their moderate to high levels of biological activity, when coupled with some toxic organic and organometallic compounds. 6 The organoboron complexes are used as a source of radicals.…”

Synthesis, experimental and theoretical characterization of Cu(II) complex of 2-chloropyrimidine

“…Also, any information about their coordinative properties can be used as a mean for explanation of the metallic role in biological systems (Löffler and Zameitat, 2004). Many complexes of transition metals with pyrimidine and its derivaties have already been synthesized and reported in the literature (Maddah et al, 2006;Blake et al, 2002;Lumme et al, 1984).…”

“…The synthesis of anti-carcinogenic complexes with metallic ions involving normally in human metabolism seems to be advantageous, since the overdose of such elements can simply be excreted from the organism (Lumme et al, 1984). On the other hand, it has been shown that the complex formation with copper ion increases the anti-carcinogenic effects of the ligands (Gokhale et al, 2001).…”

“…On the other hand, it has been shown that the complex formation with copper ion increases the anti-carcinogenic effects of the ligands (Gokhale et al, 2001). The copper complex of 2-aminopyrimidine ligand showed the anticancer properties (Lumme et al, 1984).…”