Antitoxic properties of standard dry mumijo extract

Фролова, Л. Н.; Киселева, Т. Л.; Kolkhir, V. K.; Baginskaya, A. I.; Trumpe, T.E.

doi:10.1007/bf02464208

Cited by 3 publications

(1 citation statement)

References 2 publications

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“…According to the Mongolian ancient medical treatment history, the use of mumio is effective for the treatment of over 404 diseases (Frolova et al, 1998;Galgóczy et al, 2011). Many scientific and clinical research on mumio have been performed and results have shown good treatment against respiratory diseases, laryngeal papillomatosis and inflammations, bone fracture, osteomyelitis, burns and skin diseases (Stohs et al, 2017;Talbert et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Development of dual crosslinked mumio-based hydrogel dressing for wound healing application: Physico-chemistry and antimicrobial activity

Zandraa

Ngwabebhoh

Patwa

et al. 2021

International Journal of Pharmaceutics

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Section: Introductionmentioning

confidence: 99%

Development of dual crosslinked mumio-based hydrogel dressing for wound healing application: Physico-chemistry and antimicrobial activity

Zandraa

Ngwabebhoh

Patwa

et al. 2021

International Journal of Pharmaceutics

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Cardioprotective Effect of Mumie (Shilajit) on Experimentally Induced Myocardial Injury

et al. 2014

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This study assessed the effects of mumie (shilajit) pre-treatment, a traditional drug which is well known in the ancient medicine of both east and west, on cardiac performance of rats subjected to myocardial injury. Animals were divided into control, M250, and M500 (received mumie at dosages of 250 and 500 mg/kg/day, orally for 7 days, respectively) main groups each consisting of two subgroups-with and without heart injury. On the 6th and 7th days, isoproterenol (ISO) (85 mg/kg i.p.) was injected (s.c.) to half of the animal subgroups to induce myocardial damage. On the 8th day, after hemodynamic parameter recordings, hearts were removed for further evaluation. Mumie pre-treatment had no significant effects on hemodynamic and cardiac indices of normal animals. When the cardiac injury was induced, mumie maintained the ±dp/dt maximum, attenuated the serum cardiac troponin I, and reduced the severity of cardiac lesions. Despite the mild positive effects of mumie on total antioxidant capacity and lipid proxidation index, no significant difference was observed among animal groups. The findings suggest the prominent cardioprotective effect of mumie against destructive effects of ISO. It seems that other mechanisms than reinforcements of antioxidant system are involved in this beneficial effect.

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