Antitoxic Effects of Dietary Fiber

Kritchevsky, David

doi:10.1007/978-1-4613-0519-4_27

Cited by 2 publications

(3 citation statements)

References 22 publications

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“…In addition, higher fiber content of the diet (e.g. in RSF compared with CON diet) reduces the digestibility of nutrients in the small intestine such that bulkiness and viscosity of dietary fibers may delay the hydrolysis and absorption of nutrients and allow them to travel further through the gastrointestinal tract and reach the large intestine [50]. Moreover, the plant cell wall matrix of the fibers may act as physical barrier and reduce the availability of the nutrients for digestive enzymes and bacteria [50].…”

Section: Discussionmentioning

confidence: 99%

“…in RSF compared with CON diet) reduces the digestibility of nutrients in the small intestine such that bulkiness and viscosity of dietary fibers may delay the hydrolysis and absorption of nutrients and allow them to travel further through the gastrointestinal tract and reach the large intestine [50]. Moreover, the plant cell wall matrix of the fibers may act as physical barrier and reduce the availability of the nutrients for digestive enzymes and bacteria [50]. Digestibility varies with the age of the pigs as their digestive system is developing and their gut microbiota becomes more stable with increasing fiber-fermentation capacity [3,51].…”

Section: Discussionmentioning

confidence: 99%

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Gut microbiota profiling in Norwegian weaner pigs reveals potentially beneficial effects of a high-fiber rapeseed diet

et al. 2018

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Rapeseed meal (RSM) is an alternative feed ingredient to soybean meal (SBM) in pig diets. However, knowledge on the effect of RSM on gut health, especially in relation to changes in gut microbiota is still limited. In our study, Norwegian Landrace weaner pigs were fed with either a control diet (CON) based on wheat, barley and SBM, or a high-fiber experimental diet where SBM was replaced by RSM (RSF). We found no large differences in the gut microbiota of pigs fed the two diets, suggesting that RSF does not disturb the gut microbiota and the normal gut function. The relative abundance of SCFA-producing phylotypes and colon-health related phylotypes increased in the large intestine of RSF-fed pigs. Among them, Lachnospira and Coprococcus were negatively associated with the presence of neutrophils in the colon wall. The higher abundance of these bacteria in colon of RSF pigs may suggest an anti-inflammatory stimulus effect of the RSF diet. The gut microbiota of RSF-fed pigs was relatively unaltered following episodes of diarrhea suggesting that the RSF diet may promote robustness in weaner pigs and reduce the risk of dysbiosis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Gut microbiota profiling in Norwegian weaner pigs reveals potentially beneficial effects of a high-fiber rapeseed diet

et al. 2018

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“…The whole body model for cholesterol metabolism developed by McAuley et al (2012), 26 which includes the intestine, liver, and peripheral and blood compartments, was adopted. From the literature, [27][28][29][30][31] we know that other factors such as dietary nutrients and components along with lifestyle effects also play a signicant role in determining cholesterol levels in the body. The effects of dietary components upon cholesterol metabolism were taken from the system dynamics model created by Demirezen & Barlas (2009).…”

Section: Model Development and Analysismentioning

confidence: 99%