Antistress activity of Argyreia speciosa roots in experimental animals

Patel, Nikunj B.; Galani, Varsha J; Patel, Bharatkumar G

doi:10.4103/0975-9476.85551

Cited by 13 publications

(8 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It plays an important role in central integration of hypothalamic-pituitary-adrenocortical (HPA) stress reaction. None adequate level of GABA in plasma has been related to the development of acute posttraumatic stress disorder [ 21 , 22 ]. On the other hand, previous study has reported that ethanol extract of Rubia cordifolia can stimulate the brain GABA level that subsequently reduced the dopamine and plasma corticosterone levels [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

In VivoAntistress and Antioxidant Effects of Fermented and Germinated Mung Bean

Yeap

Beh

Ali

et al. 2014

BioMed Research International

View full text Add to dashboard Cite

Mung bean has been traditionally used to alleviate heat stress. This effect may be contributed by the presence of flavonoids and γ-aminobutyric acid (GABA). On the other hand, fermentation and germination have been practised to enhance the nutritional and antioxidant properties of certain food products. The main focus of current study was to compare the antistress effect of none-process, fermented and germinated mung bean extracts. Acute and chronic restraint stresses were observed to promote the elevation of serum biochemical markers including cholesterol, triglyceride, total protein, liver enzymes, and glucose. Chronic cold restraint stress was observed to increase theadrenal gland weight, brain 5-hydroxytryptamine (5-HT), and malondialdehyde (MDA) level while reducing brain antioxidant enzyme level. However, these parameters were found reverted in mice treated with diazepam, high concentration of fermented mung bean and high concentration of germinated mung bean. Moreover, enhanced level of antioxidant on the chronic stress mice was observed in fermented and germinated mung bean treated groups. In comparison between germinated and fermented mung bean, fermented mung bean always showed better antistress and antioxidant effects throughout this study.

show abstract

Section: Discussionmentioning

confidence: 99%

In VivoAntistress and Antioxidant Effects of Fermented and Germinated Mung Bean

Yeap

Beh

Ali

et al. 2014

BioMed Research International

View full text Add to dashboard Cite

show abstract

“…Several other studies have also been reported that the plants having anti-stress property will reduce the number of writhes. [ 2 26 ]…”

Section: Discussionmentioning

confidence: 99%

“…A number of studies have reported the same result. [ 2 24 26 ] Stress-induced rise in blood glucose, total cholesterol and triglyceride levels were significantly reduced by both extracts of R. diffusa at a dose of 300 mg/kg b.w. indicating their anti-stress potential.…”

Section: Discussionmentioning

confidence: 99%

Effect of whole plant of Rostellularia diffusa Willd. on experimental stress in mice

Nagasirisha¹,

Saleem²

2014

Phcog Mag

View full text Add to dashboard Cite

Background:Rostellularia diffusa is an unexplored medicinal plant used as brain tonic in traditional medicine system.Objective:This study was designed to investigate the antioxidant and anti-stress potential of R. diffusa by experimental animal models.Materials and Methods:The extracts of R. diffusa were subjected to preliminary phytochemical screening and high performance thin layer chromatography (HPTLC) finger printing analysis. The antioxidant potential of the extracts was found by different in vitro models. The anti-stress activity was investigated by using acetic acid induced writhing test, swimming endurance test, and restraint stress in experimental mice. Serum parameters such as glucose, triglyceride and cholesterol, oxidative stress parameter thiobarbituric acid reactive substance, antioxidant parameters such as reduced glutathione, superoxide dismutase and catalase and organ weights were evaluated after restraint stress in mice. Diazepam was used as reference standard to compare the anti-stress activity of plant extract.Results:High performance thin layer chromatography finger printing analysis revealed the presence of flavone compounds in both extracts. The extracts also showed good antioxidant property in different in vitro antioxidant models. Administration of extracts of R. diffusa decreased the number of wriths and immobility time when compared with control group in acetic acid-induced writhing test and swimming endurance test respectively in experimental mice. They also suppressed the restraint stress-induced alterations in serum parameters, oxidative stress, and antioxidant parameters in brain and also restored the organ weights in normal level.Conclusion:From these results, it has been concluded that the potential anti-stress activity of R. diffusa is through its adaptogenic and antioxidant properties.

show abstract

“…However, the pace of modern life, the constant effect on the body of adverse exogenous and endogenous factors (noise, vibration, bacterial toxins, viruses, radiation, microwaves), as well as intense social the situation can be stressprovocative factors (Patel et al, 2011;Oladipo and Ibukun, 2016.). Stress beyond physiological adaptation is sharply negative and adversely affects activities of organs and systems, primarily those in which there is a high metabolic activitythe brain and myocardium, as well as the thymolymphatic apparatus (Oladipo and Ibukun, 2016).…”

Section: Evaluation Of the Studied Extracts Effect On The Change In The Mitochondrial Function Of The Rat Brain And Myocardium Under Acutmentioning

confidence: 99%

Anti-Stress Activity of Some Plants Extracts of the North Caucasus Flora

Pozdnyakov

Adzhiahmetova²,

Chervonnaya³

et al. 2020

Indonesian J. Pharm.

View full text Add to dashboard Cite

To date, stress is a common medical and socially significant disease that requires rational pharmacotherapeutic correction.The anti-stress properties of ethnolic and aqueous extracts obtained from leaves of Ribes nigrum L., inflorescences of Gaillardia pulchella Foug., stems of Lysimachia punctata L were studied in this work. Acute stress was modeled by immobilization of rats for 2h. The test-extracts were administered per os prophylactically in a dose of 1/20 of LD50 (2000mg/kg). The following parameters were evaluated: organs mass coefficient (adrenal glands, thymus, spleen), the number of stomach erosion; the biochemical changes in the blood serum (adrenaline, cortisol, total protein and glucose concentration); the mitochondrial function parameters in brain and myocardium (evaluation of mitochondrial pore transitional permeability opening and mitochondrial membrane potential). 70% ethanol extract from Gaillardia pulchella Foug. inflorescences has the highest anti-stress activity, the course application of which contributed to the normalization of the weight index of organs, a decrease in glucose concentration by 64.5% (p <0.05), and cortisol by 73.7% (p <0.05) and adrenaline -78.9% (p <0.05) in the blood, an increase in total protein level by 62.5% (p <0.05) and stabilization of mitochondrial function. The study showed a high anti-stress activity of 70 % ethanol extract from Gaillardia pulchella Foug. inflorescences.

show abstract

Antistress activity of Argyreia speciosa roots in experimental animals

Cited by 13 publications

References 32 publications

In VivoAntistress and Antioxidant Effects of Fermented and Germinated Mung Bean

In VivoAntistress and Antioxidant Effects of Fermented and Germinated Mung Bean

Effect of whole plant of Rostellularia diffusa Willd. on experimental stress in mice

Anti-Stress Activity of Some Plants Extracts of the North Caucasus Flora

Contact Info

Product

Resources

About