Antispasmodic Effects ofBauhinia microstachya. on Isolated Smooth Muscle

Chemical composition and biological potential of plants from the genusBauhinia

“…Similarly, Damasceno et al (2004) determined the effects of diabetes on the defense system against oxidative stress in pregnant female rats, and evaluated the influence of the B. forficata extract on the antioxidant system, glycemic control, hepatic glycogen, cholesterol, triglycerides, total proteins and lipids. The results showed that experimental diabetes induced by streptozotocin in female rats causes repercussions in the antioxidant defense system, with an increase in uric acid and a decrease in glutathione and superoxide dismutase De Sousa et al, Lino et al, 2004Lim et al, 2006Reid et al, 2006Aderogba et al, 2007Muñoz et al, 2000Kittakoop et al, 2000Menezes et al, 2004Ramos et al, 2005Macedo et al, 2007Argolo et al, 2004Pettit et al, 2006El-Khatiba and Khaleel, 1995Gupta et al, 2005Kumar et al, 2005Gupta et al, 2004bGupta et al, 2004aAkthar and Ahmad, 1995Dhar et al, 1968Apisantiyakom et al, 2004Hazra and Chatterjee, 2008Braca et al, 2001Aswal et al, 1984Rajkapoor et al, 2003bRajkapoor et al, 2003aMacedo et al, 2007Rajkapoor et al, 2006Bodakhe and Ram, 2007 Biological properties activity, and that treatment of pregnant diabetic female rats with B. forficata did not control maternal hyperglycemia, hyperlipidemia or hypercholesterolemia, but it did increase the amount of hepatic glycogen, decreased the uric acid concentration, and increased the glutathione activity. This suggests that the extract of the plant acts as an antioxidant defense system, probably due the presence of the previously detected flavonoids (da Silva et al, 2000;da Silva and Cechinel Filho, 2002;Pizzolatti et al, 2003).…”