Antispasmodic and relaxant effects of the hidroalcoholic extract of Pimpinella anisum (Apiaceae) on rat anococcygeus smooth muscle

Tirapelli, Carlos Renato; Andrade, Cláudia Roberta de; Cassano, Adriano Oliano; Souza, Fernando Almeida de; Ambrósio, Sérgio Ricardo; Costa, Fernando B. Da; Oliveira, Ana Maria de

doi:10.1016/j.jep.2006.08.031

Cited by 71 publications

(34 citation statements)

References 21 publications

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“…Examining the supposed pharmacological properties of the plants most cited by the patients, reveals that the majority are used as antispasmodics, tranquilizers or antiinflammatory drugs (Abuhamdah et al 2008;Tirapelli et al, 2007;McKay, Blumberg, 2006). These properties could contribute to the control of asthma symptoms, but should not be indicated for treatment of this disease due lack of evidence of their efficacy and safety.…”

Section: Discussionmentioning

confidence: 99%

Use of medicinal herbs by patients with severe asthma managed at a Referral Center

Mega

Santos

Souza‐Machado³

et al. 2011

Braz. J. Pharm. Sci.

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Asthma is a chronic inflammatory disease of the airways that may lead to limitations in regular activities, to hospitalizations and a decrease in quality of life. Adherence to drug treatment is crucial for control of the disease. The use of medicinal herbs can reduce adherence to prescriptions, as the medication may be replaced by infusions or herbal products. The objective of this study was to evaluate the frequency of use of traditional herbal medicine among severe asthmatics in Salvador. Information on use of homemade remedies was obtained through application of a questionnaire during patient visits to a referral center. We also collected data on economic and social aspects as well as disease control. One hundred and forty-four (91,1%) out of one hundred and fifty-eight patients evaluated used herbal medicines, but only 26.5% attributed improvement of asthma symptoms to this alternative treatment and only 8 had substituted a prescribed medication by herbal medicines. There was a trend towards lower adherence to prescription drug treatment in this group of patients. Despite the high frequency of use of medicinal herbs in our sample, there was no improvement in the asthma treatment in this population compared to non-users. Adherence to conventional drug treatment was satisfactory and there was neither reduction in asthma control nor increase in hospitalizations among the users of medicinal plants.Uniterms: Asthma/adherence to drug treatment. Medicinal herbs/use.A asma é uma enfermidade inflamatória crônica das vias aéreas que pode resultar em limitações nas atividades diárias, internações e prejuízo da qualidade de vida. A adesão ao tratamento medicamentoso é fundamental para o controle da doença. O uso de plantas medicinais pode reduzir a adesão ao tratamento prescrito, à medida que os medicamentos são substituídos por chás ou ervas. O objetivo deste estudo foi avaliar a frequência de uso de plantas medicinais entre asmáticos graves em Salvador. As informações sobre uso de remédios caseiros foram obtidas por meio de questionário durante a visita dos pacientes a um centro de referência. Foram coletados dados econômicos, sociais e de controle da doença. Cento e quarenta e quatro (91,1%) dos cento e cinqüenta e oito pacientes avaliados utilizavam plantas medicinais, dos quais apenas 26,5% atribuíam melhora dos sintomas da asma a este tratamento alternativo e somente 8 pacientes já haviam feito a substituição de medicamento por alguma planta medicinal. Houve tendência a menor adesão ao tratamento medicamentoso neste grupo de pacientes. Apesar da alta frequência do uso de plantas medicinais na nossa amostra, não houve melhora no tratamento da asma desta população em relação aos não-usuários. A adesão ao tratamento medicamentoso foi satisfatória, não havendo piora no controle da asma ou aumento em hospitalizações entre os usuários de plantas medicinais.Unitermos: Asma/adesão ao tratamento medicamentoso. Plantas medicinais/uso.

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Section: Discussionmentioning

confidence: 99%

Use of medicinal herbs by patients with severe asthma managed at a Referral Center

Mega

Santos

Souza‐Machado³

et al. 2011

Braz. J. Pharm. Sci.

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“…In addition, there are more essential oils in the aniseed fruit than in the seeds of Cirque du Soleil. Aniseed volatile oil medicine and pharmacy; Antispasmodic, antioxidant, antimicrobial, insecdicidal and antifungal properties (Özcan & Chalchat, 2006;Tirapelli et al, 2007;Zeybek & Zeybek, 1994). Anason is used medically in dissipative complaints, in the treatment of influenza and as a mild sputum remover (Blumenthal, 2000).…”

Section: Aniseedmentioning

confidence: 99%

The examination of spices used in the Ottoman palace cuisine

2017

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The human being has a vital prescription to eat and drink as much as the day-to-day process. This vital point constitutes the foundation stone of gastronomic tourism. In our globalized world, nations that express or offer their own values have become more successful. Therefore, the culture of Turkish food and nutrition refers as the key of national culture. Therefore, it is very important to examine the characteristics of the Ottoman cuisine to introduce food culture. Traditionally Ottoman cuisine, soups, meat dishes, olive oil vegetables, salads and spices used in desserts are important. Nowadays, people want to learn not only the sense of hunger but also the history of gastronomy (all components depending on cultural and environmental influences). It gives us great opportunities when it is told and applied to the history of that cultural gastronomy. These opportunities are making economic difference by strengthening the functions of gastronomic tourism. Due to the literature obtained in the study, it is thought that the inclusion of the spices in the Ottoman cuisine destinations in Turkey, which has a high potential for gastronomy tourism, will support sustainable development. In the study, was given informations about the characteristics of the spices used in Ottoman cuisine.

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“…In the food industry, anise is used as flavouring and aromatic agent for fish products, ice cream, sweets, and gums 88,89 . Antispasmodic and relaxant effects of three hydroalcoholic extracts of the aerial parts of Pimpinella anisum (ethanol: water; 40 : 60, 60 : 40, and 80 : 20) were investigated on rat anococcygeus smooth muscle 90 ( Figure 6). The laxative efficacy of a phytotherapeutic compound containing Pimpinella anisum L., Foeniculum vulgare Miller, Sambucus nigra L., and Cassia augustifolia was studied in a randomized clinical trial included 20 patients presenting with chronic constipation 91 .…”

Section: Pimpinella Anisum L Therapeutic Uses and Spasmolytic Activimentioning

confidence: 99%

Spasmolytic Potential of Some Medicinal Plants Belonging to Family Umbelliferae: A Review

Saini¹,

Singh²,

Nagori³

2014

Int. J. Res. Ayurveda Pharm.

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Gastrointestinal spasm is one of the most common gastrointestinal problems in infants. An herbal product is safe and effective gastrointestinal remedy to fight against various gastrointestinal problems. Polyherbal products are in use for the treatment of gastrointestinal problems since ancient time. Current era has witnessed an interest in homemade remedies. A large number of modern drugs have been developed from plants. The objective of this review is to provide a consolidated report on traditional uses and spasmolytic activities of some medicinal plants of umbelliferae family viz. Anethum graveolens, Apium graveolense, Foeniculum vulgare, Cuminum cyminum , Pimpinella anisum, Coriandrum sativum and Trachyspermum ammi have been extensively used for various gastrointestinal problems. Gastrointestinal spasm treatment is most common application of these plants oils.

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Antispasmodic and relaxant effects of the hidroalcoholic extract of Pimpinella anisum (Apiaceae) on rat anococcygeus smooth muscle

Cited by 71 publications

References 21 publications

Use of medicinal herbs by patients with severe asthma managed at a Referral Center

Use of medicinal herbs by patients with severe asthma managed at a Referral Center

The examination of spices used in the Ottoman palace cuisine

Spasmolytic Potential of Some Medicinal Plants Belonging to Family Umbelliferae: A Review

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