2015
DOI: 10.1016/j.bjp.2015.09.005
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Antischistosomal activity from Brazilian marine algae

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Cited by 8 publications
(9 citation statements)
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“…L. dendroidea extracts were previously selected for bioguided fractionation together with other algal species in our trial studies [9,10]. In the present study, extracts of L. dendroidea, as shown in the GC-MS chromatograms in the 20-60 min range (Figure 2), revealed samples to be complex mixtures that contained a wide variety of volatile compounds from different chemical classes according to searches of various GC-MS libraries.…”
Section: Bioguided Fractionation Of Laurencia Dendroidea Led To Elatolmentioning
confidence: 54%
See 1 more Smart Citation
“…L. dendroidea extracts were previously selected for bioguided fractionation together with other algal species in our trial studies [9,10]. In the present study, extracts of L. dendroidea, as shown in the GC-MS chromatograms in the 20-60 min range (Figure 2), revealed samples to be complex mixtures that contained a wide variety of volatile compounds from different chemical classes according to searches of various GC-MS libraries.…”
Section: Bioguided Fractionation Of Laurencia Dendroidea Led To Elatolmentioning
confidence: 54%
“…Recently, we detected the in vitro activity of seaweed extracts against S. mansoni. Three out of the thirteen tested extracts induced lethal effects in the exposed worms [9]. In a more comprehensive screening, in addition to the effects on S. mansoni, the molluscicidal activity was evaluated, indicating the activity of 22 out of 37 species in at least one of the models [10].…”
Section: Introductionmentioning
confidence: 99%
“…Recently, we detected the in vitro activity of seaweed extracts against S. mansoni . Three out of the 13 tested extracts induced lethal effects in the exposed worms [ 19 ]. In the present study, a more comprehensive trial was performed with the screening of 37 species of Brazilian macroalgae for schistosomicidal and molluscicidal activity searching for compounds of potential use in the treatment and control of schistosomiasis.…”
Section: Introductionmentioning
confidence: 99%
“…Sources of new drugs for the treatment of protozoal infections can be natural products, synthetic molecules, or existing drugs with an extended spectrum of indications. A combination of new methods, including genetic modification of pathogens, bioimaging, molecular docking [7], and robotics has led to the standardization of high-throughput screening platforms for drug discovery [8]. For the treatment of protozoal infections, new effective agents are needed which do not cause at all or cause a minimum of side effects and to which protozoa will not develop resistance in a short time.…”
Section: Introductionmentioning
confidence: 99%