Antiresorptive therapy and dental implant survival: an up to 20-year retrospective cohort study in women

Cheng, Yu-Chi; Ewers, Rolf; Morgan, Katherine; Hirayama, Muneki; Murcko, Laura; Morgan, John P.; Bergamo, Edmara Tatiely Pedroso; Bonfante, Estevam Augusto

doi:10.1007/s00784-022-04609-4

Cited by 7 publications

(5 citation statements)

References 66 publications

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“…30 Another study revealed that for this implant system, antiresorptive drug use in women significantly improves long-term implant survival. 31 In addition to aspects related to the implant's design, a previous study that investigated more than 90 covariates concluded that several patient and prosthesis-related factors were significantly associated with crestal bone gain around single-tooth locking taper implants. Two of these factors were the use of a prefabricated titanium abutment with a hemispherical base, and the daily intake of NSAIDs.…”

Section: Discussionmentioning

confidence: 99%

“…Several distinctive features of the implant system have been proven to promote healthy bone metabolism: a bacterially sealed implant‐abutment interface 28 ; a short implant design, that dissipates strain over a large area 29 ; and a unique healing mechanism that results in a haversian‐like bone configuration 30 . Another study revealed that for this implant system, antiresorptive drug use in women significantly improves long‐term implant survival 31 . In addition to aspects related to the implant's design, a previous study that investigated more than 90 covariates concluded that several patient and prosthesis‐related factors were significantly associated with crestal bone gain around single‐tooth locking taper implants.…”

Section: Discussionmentioning

confidence: 99%

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Prefabricated shouldered abutments enable successful restoration of molar crowns on implants

Cheng,

Perpetuini,

Marincola

et al. 2024

Clin Implant Dent Rel Res

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PurposeThis retrospective study evaluated the effect of selected clinical and patient factors on survival, success, and peri‐implant bone level changes of locking taper implants supporting molar crowns on Bicon's prefabricated shouldered abutments.MethodsA total of 234 patients, who received 274 single molar crowns supported by locking taper implants were included in this retrospective study. Kaplan–Meier survival analysis was used to assess overall implant survival, prostheses survival, and success. Crowns were either monolithic (resin based) or bilayered (milled fiber‐reinforced composite coping veneered with indirect composite). Early and late changes in marginal bone levels were plotted and analyzed with equivalence testing to compare the effects of different factors on crestal bone levels.ResultsAt 9.5 years after implant surgery, the implant survival probability was 94.2%, the probability of prosthesis survival was 91.4%, and the probability of prosthetic success was 90.4%. Neither the use of different crown materials, nor the choice of monolithic versus bilayered crown construction, significantly affected the probability of prosthetic success. Marginal bone levels, on average, trended downwards towards the top of the implant within the first 2 years after functional loading, and remained stable on average, since then. Factors affecting bone levels included the use of nonsteroidal anti‐inflammatory drugs, which precluded early implant bone loss; and subcrestal implant placement, which was linked to significantly higher long‐term bone levels.ConclusionThe implant and abutment system studied resulted in high implant and prosthetic survival rates, regardless of prosthetic material used, with stable bone levels over time.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Prefabricated shouldered abutments enable successful restoration of molar crowns on implants

Cheng,

Perpetuini,

Marincola

et al. 2024

Clin Implant Dent Rel Res

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“…Происходит активная выработка провоспалительных цитокинов ФНО-α и ИЛ-6, провоцирующих образование остеокластов, что приводит к развитию системного воспаления [23], общие механизмы которого были описаны ранее. Однако существуют данные о том, что имплантаты, установленные пациентам, принимающим пероральное антирезорбтивное лечение, показали высокий процент приживаемости, в сравнении с пациентами, которые не проходили данный курс лечения [27,28]. Было выявлено, что остеоинтеграция, общая приживаемость имплантатов, незначительная потеря костной массы и состояние мягких тканей ведут себя не иначе, чем в группе здоровых пациентов [29].…”

Section: ав гусь ков аа олейников аа никифоро в вг логункова дг жуков...unclassified

Influence of factors of systemic inflammation and endothelial dysfunction in somatic pathologies on the success of dental implantation (literature review)

Guskov,

Oleynikov,

Nikiforov

et al. 2023

APPLIED

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In the presented literature review, the issue of the influence of general somatic factors associated with diseases of the cardiovascular and endocrine systems on the success of dental implantation was studied. The issues of the relationship of systemic inflammatory processes and periodontal status with the dental health of patients with background pathologies associated with an imbalance of pro- and anti-inflammatory cytokines, insulin and glucose in the blood in diabetes mellitus and obesity, factors of endothelial dysfunction in atherosclerosis, hypertension and coronary heart disease are highlighted. Based on the analyzed information, it was confirmed that poor-quality history taking, the lack of a thorough diagnostic examination (biochemical blood test, coagulogram, reaction to the presence of specific infections and viral diseases), ignoring the need to correct existing local and systemic inflammatory phenomena before dental implantation can lead to a violation the process of osseointegration, the occurrence of peri-implantitis, implant rejection reactions. In this regard, it can be concluded that when planning complex dental treatment, attention should be paid not only to local dental symptoms, but also to the general history and laboratory data, which will improve the quality of dental implantation.

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“…Although preventing dental diseases is the preferable way to avoid long, uncomfortable, and expensive dental care, some conditions are inevitable, such as tooth agenesis, tooth loss due to trauma, amelogenesis, dentinogenesis imperfecta, or severe chemotherapy treatment that may negatively impact the quality of the bone that supports the teeth or implants. 4 , 5 On the other hand, several patients have eagerly sought dental clinics exclusively for aesthetic reasons. As a result of the technological advancements in dental prostheses and restoration materials processes, the market share of dental materials had been projected to reach USD 8.06 billion by 2027, prior to the COVID-19 outbreak.…”

Section: Introductionmentioning

confidence: 99%

An engineering perspective of ceramics applied in dental reconstructions

et al. 2023

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The demands for dental materials continue to grow, driven by the desire to reach a better performance than currently achieved by the available materials. In the dental restorative ceramic field, the structures evolved from the metal-ceramic systems to highly translucent multilayered zirconia, aiming not only for tailored mechanical properties but also for the aesthetics to mimic natural teeth. Ceramics are widely used in prosthetic dentistry due to their attractive clinical properties, including high strength, biocompatibility, chemical stability, and a good combination of optical properties. Metal-ceramics type has always been the golden standard of dental reconstruction. However, this system lacks aesthetic aspects. For this reason, efforts are made to develop materials that met both the mechanical features necessary for the safe performance of the restoration as well as the aesthetic aspects, aiming for a beautiful smile. In this field, glass and high-strength core ceramics have been highly investigated for applications in dental restoration due to their excellent combination of mechanical properties and translucency. However, since these are recent materials when compared with the metal-ceramic system, many studies are still required to guarantee the quality and longevity of these systems. Therefore, a background on available dental materials properties is a starting point to provoke a discussion on the development of potential alternatives to rehabilitate lost hard and soft tissue structures with ceramic-based tooth and implant-supported reconstructions. This review aims to bring the most recent materials research of the two major categories of ceramic restorations: ceramic-metal system and all-ceramic restorations. The practical aspects are herein presented regarding the evolution and development of materials, technologies applications, strength, color, and aesthetics. A trend was observed to use high-strength core ceramics type due to their ability to be manufactured by CAD/CAM technology. In addition, the impacts of COVID-19 on the market of dental restorative ceramics are presented.

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Antiresorptive therapy and dental implant survival: an up to 20-year retrospective cohort study in women

Cited by 7 publications

References 66 publications

Prefabricated shouldered abutments enable successful restoration of molar crowns on implants

Prefabricated shouldered abutments enable successful restoration of molar crowns on implants

Influence of factors of systemic inflammation and endothelial dysfunction in somatic pathologies on the success of dental implantation (literature review)

An engineering perspective of ceramics applied in dental reconstructions

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