2020
DOI: 10.1080/14786419.2020.1758089
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Antiproliferative, antileishmanial and antimicrobial studies on Cnidoscolus quercifolius Pohl (Euphorbiaceae)

Abstract: Cnidoscolus quercifolius is an Euphorbiaceae endemic to the northeast region of Brazil, which is used in folk medicine as anti-inflammatory, analgesic and antibiotic. An ethanolic extract was prepared with the leaves from C. quercifolius, and also partitioned and chromatographed leading to the isolation of cyanoglucoside linamarin (1), cinnamic acid (2), as well as a mixture of steroids and terpenoids (3 -6). Structural elucidation of the compounds was done by IR, MS and NMR analysis. For the cyanoglucoside (1… Show more

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Cited by 1 publication
(3 citation statements)
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“…It was observed in that study that the compound deoxofaveline was considered the most active, with IC 50 values ranging from 2.7 to 8.9 µg/mL. Faveline methyl was selective for leukemia cells (IC 50 1.6µg/mL), showing weak activity in other cells [63].…”
Section: Cytostatic Activitymentioning
confidence: 93%
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“…It was observed in that study that the compound deoxofaveline was considered the most active, with IC 50 values ranging from 2.7 to 8.9 µg/mL. Faveline methyl was selective for leukemia cells (IC 50 1.6µg/mL), showing weak activity in other cells [63].…”
Section: Cytostatic Activitymentioning
confidence: 93%
“…(E)-β-farnesene 55 Leaves, flowers GC-MS Essential oil [48] Methyl-β-(E)-ionol 56 Leaves GC-MS Essential oil [48] (E)-β-Ionene 57 Leaves GC-MS Essential oil [48] Biciclogermacrene 58 Leaves, flowers GC-MS Essential oil [48] β-Bisabolene 59 Leaves GC-MS Essential oil [48] α-Cadinene 60 Leaves, flowers GC-MS Essential oil [48] (E)-nerolidol 61 Leaves GC-MS Essential oil [48] Curcumenol 62 Leaves GC-MS Essential oil [48] Vetivenic acid 63 Leaves GC-MS Essential oil [48] Cryptomeridiol 64 Leaves, stem bark GC-MS Essential oil [48] β-Vetivone 65 Leaves GC-MS Essential oil [48] Isophytol 66 Leaves GC-MS Essential oil [48] α-Pinene 67 Flowers GC-MS Essential oil [48] Sabinene 68 Flowers GC-MS Essential oil [48] Myrcene 69 Flowers GC-MS Essential oil [48] Dehydroxy-trans-Linalool oxide 70 Flowers GC-MS Essential oil [48] Meta-mentha 1-( 7),8-diene 71 Flowers GC-MS Essential oil [48] δ-2-Carene 72 Flowers GC-MS Essential oil [48] α-Phellandrene 73 Flowers GC-MS Essential oil [48] o-Cresol methyl ether 74 Flowers GC-MS Essential oil [48] iso-sylvestrene 75 Flowers GC-MS Essential oil [48] δ-3-Carene 76 Flowers GC-MS Essential oil…”
Section: Substance Part Of the Plant Identification/isolation Techniq...mentioning
confidence: 99%
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