Antiplatelet drug selection in PCI to vein grafts in patients with acute coronary syndrome and adverse clinical outcomes: Insights from the British Cardiovascular Intervention Society database

Sirker, Alex; Kwok, Chun Shing; Kontopantelis, Evangelos; Johnson, Tom; Freeman, Philip; Belder, Mark de; Ludman, Peter; Zaman, Azfar; Mamas, Mamas A.

doi:10.1002/ccd.27493

Cathet Cardio Intervent

2018

DOI: 10.1002/ccd.27493

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Antiplatelet drug selection in PCI to vein grafts in patients with acute coronary syndrome and adverse clinical outcomes: Insights from the British Cardiovascular Intervention Society database

Alex Sirker

Chun Shing Kwok

Evangelos Kontopantelis

et al.

Abstract: Our real world national study provides no clear evidence to indicate that use of potent P2Y12 blockers in SVG PCI is associated with improved clinical outcomes.

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Cited by 4 publications

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“…Sirker et al explored the efficacy of different P2Y12 inhibitors in vein graft PCI among patients presenting with acute coronary syndrome in the United Kingdom database . A total of 8,119 patients undergoing vein graft PCI between 2007 and 2014 for acute coronary syndrome were included.…”

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confidence: 99%

Are all P2Y12 equally effective in vein graft angioplasty? A report from the UK database

Berladi

Lamelas

2018

Cathet Cardio Intervent

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confidence: 99%

Are all P2Y12 equally effective in vein graft angioplasty? A report from the UK database

Berladi

Lamelas

2018

Cathet Cardio Intervent

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A review of the use of propensity score methods with multiple treatment groups in the general internal medicine literature

Shurrab

Jackevicius

et al. 2023

Pharmacoepidemiology and Drug

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Background Propensity score (PS) methods with two treatment groups (e.g., treated vs. control) is a well‐established technique for reducing the effects of confounding in nonrandomized studies. However, researchers are often interested in comparing multiple interventions. PS methods have been modified to incorporate multiple exposures. We described available techniques for PS methods in multicategory exposures (≥3 groups) and examined their use in the medical literature. Methods A comprehensive search was conducted for studies published in PubMed, Embase, Google Scholar, and Web of Science until February 27, 2023. We included studies using PS methods for multiple groups in general internal medicine research. Results The literature search yielded 4088 studies (2616 from PubMed, 86 from Embase, 85 from Google Scholar, 1671 from Web of Science, five from other sources). In total, 264 studies using PS method for multiple groups were identified; 61 studies were on general internal medicine topics and included. The most commonly used method was that of McCaffrey et al., which was used in 26 studies (43%), where the Toolkit for Weighting and Analysis of Nonequivalent Groups (TWANG) method and corresponding inverse probabilities of treatment weights were estimated via generalized boosted models. The next most commonly used method was pairwise propensity‐matched comparisons, which was used in 20 studies (33%). The method by Imbens et al. using a generalized propensity score was implemented in six studies (10%). Four studies (7%) used a conditional probability of being in a particular group given a set of observed baseline covariates where a multiple propensity score was estimated using a non‐parsimonious multinomial logistic regression model. Four studies (7%) used a technique that estimates generalized propensity scores and then creates 1:1:1 matched sets, and one study (2%) used the matching weight method. Conclusions Many propensity score methods for multiple groups have been adopted in the literature. The TWANG method is the most commonly used method in the general medical literature.

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Risk of bradyarrhythmia related to ticagrelor: A systematic review and meta-analysis

Pujade

Perino

Mathieu

et al. 2020

Pharmacological Research

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Antiplatelet drug selection in PCI to vein grafts in patients with acute coronary syndrome and adverse clinical outcomes: Insights from the British Cardiovascular Intervention Society database

Abstract: Our real world national study provides no clear evidence to indicate that use of potent P2Y12 blockers in SVG PCI is associated with improved clinical outcomes.

Cited by 4 publications

References 23 publications

Are all P2Y12 equally effective in vein graft angioplasty? A report from the UK database

Are all P2Y12 equally effective in vein graft angioplasty? A report from the UK database

A review of the use of propensity score methods with multiple treatment groups in the general internal medicine literature

Risk of bradyarrhythmia related to ticagrelor: A systematic review and meta-analysis

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