Antiplasmodial benzophenones from the trunk latex of Moronobea coccinea (Clusiaceae)

Glycolysis Inhibitor Screening Identifies the Bis-geranylacylphloroglucinol Protonophore Moronone from Moronobea coccinea

“…The presence of a UV-active yellow char suggested that the active compound might be similar to the polyprenylated acylphloroglucinol derivatives previously isolated from this plant. 16 The active fraction was dissolved in MeOH and centrifuged. The supernatant was subsequently filtered and subjected to semi-preparative HPLC (Phenomenex Luna RP-18, 5 μm, 250 × 10 mm, MeCN with 0.1% formic acid) [87:13] which yielded 1 (83.5 mg).…”

“…At first, polycyclic polyprenylated acylphloroglucinol derivatives were believed to be responsible for this glycolysis inhibitory activity. 16 The polyprenylated benzophenones and other acylphloroglucinol derivatives isolated from Clusiaceae plants have been shown to exhibit a wide spectrum of bioactivities (cytotoxic, antimicrobial, antioxidant, and anti-inflammatory). 17 Bioassay-guided isolation led to the discovery of moronone ( 1 ), an acylphloroglucinol derivative with a previously unreported bis -geranyl-substituted carbon skeleton.…”

Superoxide dismutase and catalase activities in rat hippocampus pretreated with garcinielliptone FC fromPlatonia insignis

“…Several species are well known for their hulls manufacture due to the quality of their wood and for the healing properties of their latex used traditionally against dermatoses (Marti et al, 2009). This family is known to be a rich source of polycyclic polyprenylated acylphloroglucinols (PPAPs) with a large spectrum of biological activities (Cuesta-Rubio et al, 2005;Marti et al, 2009).…”

“…Several species are well known for their hulls manufacture due to the quality of their wood and for the healing properties of their latex used traditionally against dermatoses (Marti et al, 2009). This family is known to be a rich source of polycyclic polyprenylated acylphloroglucinols (PPAPs) with a large spectrum of biological activities (Cuesta-Rubio et al, 2005;Marti et al, 2009). Besides, some plants of Clusiaceae family have their pharmacological properties associated with the presence of xanthone derivatives, which has antioxidant and anticarcinogenic activities (Sundaram et al, 1983;Chen et al, 1996;Iinuma et al, 1996;Suksamrarn et al, 2003;Ee et al, 2008;Chomnawang et al, 2009;Hung et al, 2009).…”

Flavonol Glycoside from Psorospermum androsaemifolium

“…Several species are well-known for their hulls manufacture due to the quality of their wood and for the healing properties of their latex used traditionally for their effectiveness against dermatoses. 1 The genus Psorospermun Baker consists of trees and shrubs, and it is very similar to Vismia Vand. differing principally in the fruit.…”