Antioxidative, hypoglycaemic and hepatoprotective properties of five Vaccinium spp. berry pomace extracts

Muceniece, Ruta; Kļaviņš, Linards; Kviesis, Jorens; Jēkabsons, Kaspars; Rembergs, Reinis; Saleniece, Kristine; Dzirkale, Zane; Saulīte, Līga; Riekstiņa, Una; Kļaviņš, Māris

doi:10.3233/jbr-180351

Cited by 22 publications

(9 citation statements)

References 42 publications

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“…These preserves are gaining more and more recognition among consumers, due to fact that black chokeberry is a good source of polyphenols [ 8 ], especially anthocyanins [ 9 ]. In the last years, these compounds have attracted considerable attention because of their recognized antioxidant activity and potential in health promotion and disease prevention [ 10 , 11 , 12 ]. In epidemiological and clinical studies, aronia and its polyphenolic constituents have been associated with improved cardiovascular risk profiles.…”

Section: Introductionmentioning

confidence: 99%

The Efficacy of Black Chokeberry Fruits against Cardiovascular Diseases

Kasprzak-Drozd

Oniszczuk

Soja

et al. 2021

IJMS

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Epidemiological studies have emphasized the association between a diet rich in fruits and vegetables and a lower frequency of occurrence of inflammatory-related disorders. Black chokeberry (Aronia melanocarpa L.) is a valuable source of biologically active compounds that have been widely investigated for their role in health promotion and cardiovascular disease prevention. Many in vitro and in vivo studies have demonstrated that consumption of these fruits is associated with significant improvements in hypertension, LDL oxidation, lipid peroxidation, total plasma antioxidant capacity and dyslipidemia. The mechanisms for these beneficial effects include upregulation of endothelial nitric oxide synthase, decreased oxidative stress, and inhibition of inflammatory gene expression. Collected findings support the recommendation of such berries as an essential fruit group in a heart-healthy diet. The aim of this review was to summarize the reports on the impact of black chokeberry fruits and extracts against several cardiovascular diseases, e.g., hyperlipidemia, hypercholesterolemia, hypertension, as well as to provide an analysis of the antioxidant and anti-inflammatory effect of these fruits in the abovementioned disorders.

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Section: Introductionmentioning

confidence: 99%

The Efficacy of Black Chokeberry Fruits against Cardiovascular Diseases

Kasprzak-Drozd

Oniszczuk

Soja

et al. 2021

IJMS

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“…(2010) reported that acylated pelargonidin derivatives in red radish display concentration‐dependent reducing power and scavenging effect. Many studies have also proved that blueberry pomace and juice extracts have antioxidant and hypoglycemic effects (Muceniece et al., 2019). It may be caused by the different content and composition of anthocyanins and polyphenols in these two blueberry products.…”

Section: Resultsmentioning

confidence: 99%

Investigation on the biological activity of anthocyanins and polyphenols in blueberry

Yang

Wang

et al. 2021

Journal of Food Science

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Blueberry (Vaccinium spp.) is a fruit recognized in the world as healthy, and many of its active ingredients have important physiological functions. This study analyzed the antioxidant activity, antitumor activity, and immune function of anthocyanins and polyphenols extracted from blueberries. The crude extracts of anthocyanins and polyphenols were obtained from blueberries and then purified, and the extract exhibited excellent dose‐dependent antitumor activity and antioxidant activity in vivo and in vitro. The purified anthocyanins and polyphenol compounds showed higher antioxidant activity, whereas the crude extract had a better inhibitory effect on tumor proliferation than pure extract, and the blueberry anthocyanin and polyphenol crude product mixture showed a more powerful tumor suppressor, which may be the result of the synergistic effect of multiple compounds. The crude extracts were also more efficient at improving immune function, as reflected by measurements of change in body weight, thymus and spleen indices, macrophage phagocytosis, lymphocyte transformation capacity, superoxide dismutase activity, malondialdehyde content, and serum nitric oxide levels. These results indicate that blueberry anthocyanins and polyphenol extracts can improve immune function and reduce the metastasis and proliferation of cancer cells. This study reveals the functions of important active substances in blueberries and provides support for the development of functional health products and therapeutic drugs. Practical Application We compared the biological activity of crude and purified anthocyanins and polyphenol extracts from blueberries and tested their effects on improving immune function. This study contributes to a better understanding of the bioactivity of blueberry extracts and is valuable for further applications of blueberries in medicine.

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“…The various health-promoting properties of blueberries and bilberries are widely recognised since their consumption can reduce the risk of many infectious and degenerative disease [ 3 , 4 ]. For instance, blueberry and bilberry fruits have been used as fresh, dried and as juice for the alleviation of indications related to the gastrointestinal tract and diabetes, and herbal supplements containing these berries are available in the market as aids to improve vision and to treat diarrhoea because they have antimicrobial, anti-inflammatory and antioxidant properties [ 5 , 6 , 7 , 8 ]. The biological and pharmacological activity of blueberries and bilberries are associated with their high content of polyphenolic compounds, especially anthocyanins, and their capacity to reduce oxidative stress by scavenging free radicals [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Trace Element Concentration and Stable Isotope Ratio Analysis in Blueberries and Bilberries: A Tool for Quality and Authenticity Control

Kļaviņš

Maaga

Bērtiņš

et al. 2021

Foods

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Vaccinium genus berries—wild bilberries (Vaccinium myrtillus L.) and cultivated highbush blueberries (Vaccinium corymbosum L.)—are consumed worldwide, and their consumption has a trend of stable increase. Thus, considering their wide use in ethnomedicine, for juice and jam production, as functional food, as well as their use in preparations of extracts which have application potential in pharmaceutical and cosmetics industries, studies regarding the composition of these berries are of special importance. The aim of this study is to characterise the elemental and isotopic composition, as well as variation in element concentration in bilberries gathered from different sites in Northern Europe and in commercially available blueberry samples from across the World. Furthermore, our aim was to develop tools for authenticity and quality control of these berries. The elemental composition of berries was analysed using inductively coupled plasma with optical emission detection (ICP-OED), while isotope ratio mass spectrometry (IRMS) was used for the determination of isotope ratio values. The results demonstrated detectable differences between macro- and microelement values in bilberries. IRMS analysis of blueberries revealed significant differences in isotope ratios based on the place of origin, indicating the possibility to use this analytical method for authenticity testing. In none of the samples, pollution was detected, even though there were indications of different growth conditions and geochemical differences affecting bilberry composition.

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Antioxidative, hypoglycaemic and hepatoprotective properties of five Vaccinium spp. berry pomace extracts

Cited by 22 publications

References 42 publications

The Efficacy of Black Chokeberry Fruits against Cardiovascular Diseases

The Efficacy of Black Chokeberry Fruits against Cardiovascular Diseases

Investigation on the biological activity of anthocyanins and polyphenols in blueberry

Trace Element Concentration and Stable Isotope Ratio Analysis in Blueberries and Bilberries: A Tool for Quality and Authenticity Control

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