Antioxidative effect of melatonin on cryopreserved chicken semen

Appiah, Michael Osei; He, Beibei; Lu, Wenfa; Wang, Jun

doi:10.1016/j.cryobiol.2019.05.001

Cited by 41 publications

(21 citation statements)

References 48 publications

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“…Melatonin (ME), N-acetyl-5-methoxytryptamine, has also been tested in chicken semen extenders [ 69 , 70 ]. This antioxidant is known to preserve mitochondrial integrity and helps to maintain cellular function, neutralizing the toxic effects of ROS and reactive nitrogen species [ 71 ].…”

Section: Effect Of Adding External Antioxidants To Diluents On Antioxidant Systems and Semen Quality During Storage And Cryopreservationmentioning

confidence: 99%

“…Melatonin supplementation contributed to fewer apoptotic-like changes and greater motility of thawed sperm cells [ 70 ]. Appiah et al [ 69 ] detected a positive effect of ME on chicken sperm motility, reporting that it shielded sperm membrane integrity and acrosome integrity, augmented antioxidant activity of enzymes, and reduced oxidative stress during cryopreservation.…”

Section: Effect Of Adding External Antioxidants To Diluents On Antioxidant Systems and Semen Quality During Storage And Cryopreservationmentioning

confidence: 99%

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Supplementation of Avian Semen Extenders with Antioxidants to Improve Semen Quality—Is It an Effective Strategy?

Partyka

Niżański

2021

Antioxidants

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Oxidative stress in sperm is a phenomenon related to the increasing rate of oxidation of cellular components and the excessive production of reactive oxygen species (ROS). The high content of polyunsaturated fatty acids in bird sperm cell membranes renders these cells particularly susceptible to lipid peroxidation (LPO). Therefore, to ensure the proper functioning of cells, it is necessary to have a balance between the formation of ROS and the protective action of the antioxidant system. This review aims firstly to briefly introduce the antioxidant system characteristics of avian semen. Secondly, we summarize the recent knowledge regarding progress in extender supplementation using antioxidants and other compounds to improve avian semen quality parameters and fertility rates. The review focuses on enzymes, vitamins, amino acids, proteins, some plant extracts, and other compounds that can be used to supplement the extenders to reduce the formation of oxidants in poultry semen and maintain its quality and enhance its fertility.

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Section: Effect Of Adding External Antioxidants To Diluents On Antioxidant Systems and Semen Quality During Storage And Cryopreservationmentioning

confidence: 99%

Section: Effect Of Adding External Antioxidants To Diluents On Antioxidant Systems and Semen Quality During Storage And Cryopreservationmentioning

confidence: 99%

Supplementation of Avian Semen Extenders with Antioxidants to Improve Semen Quality—Is It an Effective Strategy?

Partyka

Niżański

2021

Antioxidants

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“…Antioxidants consist of a broad class of substances and molecules with varying physio-chemical properties that dictate their specificity, localization and/or ROS-scavenging roles [238,239]. Mitochondria-targeted antioxidants, MitoTEMPO [214] and melatonin [240,241] are potent antioxidants that prevent oxidative stress-associated damages encountered during cryopreservation. Melatonin in particular, has performed unexpectedly well by exerting its ROS-ameliorating properties through its multi-faceted mechanisms [242].…”

Section: Moving Forwardmentioning

confidence: 99%

The roles of reactive oxygen species and antioxidants in cryopreservation

2019

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Cryopreservation has facilitated advancement of biological research by allowing the storage of cells over prolonged periods of time. While cryopreservation at extremely low temperatures would render cells metabolically inactive, cells suffer insults during the freezing and thawing process. Among such insults, the generation of supra-physiological levels of reactive oxygen species (ROS) could impair cellular functions and survival. Antioxidants are potential additives that were reported to partially or completely reverse freeze-thaw stress-associated impairments. This review aims to discuss the potential sources of cryopreservation-induced ROS and the effectiveness of antioxidant administration when used individually or in combination.

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“…In order to alleviate the oxidative stress caused by this imbalance, adding antioxidants to the diluent has become a necessary means [ 4 ]. Adding antioxidants has been found to improve semen quality in many species [ 5 , 6 , 7 , 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Oligomeric Proanthocyanidins and Bamboo Leaf Flavonoids Improve the Quality of Bull Semen Cryopreservation

Wang

et al. 2022

Molecules

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It is important to inhibit oxidative stress to maintain sperm motility during cryopreservation. The present study was performed to investigate the effects of supplementing oligomeric proanthocyanidins (OPC) and bamboo leaf flavonoids (BLF) or their combination as an extender for Simmental bull semen freezing. OPC, BLF, or their combination were added to the frozen diluent of bovine semen. Afterwards, computer-assisted semen analysis (CASA), detection of membrane functionality, acrosome integrity, mitochondrial integrity, CAT, SOD, GSH-PX, MDA, and ROS were conducted. The results showed that adding 50 mg/L OPC or 4 mg/L BLF could improve the quality of frozen sperm. Compared with 50 mg/L OPC alone, the combination of 50mg/L OPC and 2 mg/L BLF significantly increased the kinematic parameters of sperm, and sperm CAT, GSH-PX and SOD levels (p < 0.05), whereas the MDA of sperm was decreased (p < 0.05). These results indicated that compared to the addition of 50 mg/L OPC alone, a combination of 50 mg/L OPC and 2 mg/L BLF could further improve the quality of frozen semen. The results could provide theoretical data support for the development of a new protective agent and are significant for the cryopreservation of bovine semen in the future.

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Antioxidative effect of melatonin on cryopreserved chicken semen

Cited by 41 publications

References 48 publications

Supplementation of Avian Semen Extenders with Antioxidants to Improve Semen Quality—Is It an Effective Strategy?

Supplementation of Avian Semen Extenders with Antioxidants to Improve Semen Quality—Is It an Effective Strategy?

The roles of reactive oxygen species and antioxidants in cryopreservation

Oligomeric Proanthocyanidins and Bamboo Leaf Flavonoids Improve the Quality of Bull Semen Cryopreservation

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