Antioxidant responses of triangle sail mussel Hyriopsis cumingii exposed to harmful algae Microcystis aeruginosa and high pH

Liu, Yimeng; Li, Lei; Zheng, Liang; Fu, Ping; Wang, Yu; Nguyen, Huong Minh; Shen, Xiaosheng; Sui, Yanming

doi:10.1016/j.chemosphere.2019.125241

Cited by 40 publications

(13 citation statements)

References 43 publications

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“…This is consistent with the previous studies that glutathione depletion limited the ability to detoxify or prevent oxidative damage in organisms [51]. GST belongs to the family of multifunctional proteins, which plays a key role in the detoxification of organisms under the stress of harmful xenobiotic and endobiotic compounds [50]. In this study, the activity of GST was upregulated significantly from 48 h until the end of the experiment in hepatopancreas, while was only upregulated significantly at 72 h in gills.…”

Section: Discussionsupporting

confidence: 93%

“…GSH is the most abundant intracellular low molecular weight antioxidant in the antioxidant system. GSH can directly scavenge singlet oxygen and hydroxyl radicals to intact cells under oxidative stress, and is used as a cofactor for the biotransformation enzymes GST and the antioxidative enzyme GPx [49,50]. In our study, the GSH increased much more in gills than that in hepatopancreas, which may be because the consumption of GSH as a substrate is almost the same as that induced by oxidative stress in hepatopancreas.…”

Section: Discussionmentioning

confidence: 49%

“…With the time elapsed, the contents of MDA in hepatopancreas and gills were upregulated significantly. The phenomenon implied that although ammonia triggered the antioxidant response, it could not avoid oxidative damages [21,50]. Previous study also suggested that the increase of antioxidant enzyme activity in a short time was not sufficient to complete against stress-induced cellular damage along with the treatment duration [54].…”

Section: Discussionmentioning

confidence: 98%

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Effects of Acute Ammonia Stress on Antioxidant Responses, Histopathology and Ammonia Detoxification Metabolism in Triangle Sail Mussels (Hyriopsis cumingii)

Zhao

Feng

Zhang

et al. 2021

Water

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Ammonia is one of the major pollutants in the aquatic ecosystem. Hyriopsis cumingii has great potential for the restoration of eutrophic water. However, there is no study investigating the effect of ammonia exposure in H. cumingii. The median lethal concentration (96 h LC50) of unionized ammonium was 12.86 mg/L in H. cumingii. In the study, H. cumingii were exposed to 6.43 mg L−1 unionized ammonium (1/2 96 h LC50) for 0, 6, 12, 24, 48, 72, and 96 h. High environment ammonia induced antioxidant response to protect the body from oxidative damage. After exposure to ammonia, there was a same trend of induction followed by inhibition of the activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and glutathione-S-transferases (GST) in the hepatopancreas and gills of H. cumingii. However, the antioxidant response could not completely counteract the oxidation effect during the exposure period, resulting in lipid peroxidation (LPO) and tissue injury in the hepatopancreas and gills of H. cumingii eventually. Moreover, this study indicated that glutamine synthetase (GS), glutamate dehydrogenase (GDH), alanine aminotransaminase (ALT), and aspartate aminotransaminase (AST) in the hepatopancreas and gills may play an important role in ammonia detoxification of H. cumingii. Our results will be helpful to understand the mechanism of aquatic toxicology induced by ammonia in shellfish.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 49%

Section: Discussionmentioning

confidence: 98%

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Effects of Acute Ammonia Stress on Antioxidant Responses, Histopathology and Ammonia Detoxification Metabolism in Triangle Sail Mussels (Hyriopsis cumingii)

Zhao

Feng

Zhang

et al. 2021

Water

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“…Thus, it is important to investigate the coactions of these variables, which may result in multifactorial responses [ 52 , 53 , 54 , 55 , 56 ]. While studies about the effect of individual environmental change stressors on aquatic organisms have been widely reported, such as temperature [ 39 ], acidification [ 57 ] and salinity [ 58 ], research assessing their combined impacts have rarely been studied. Herein, the environmental changes regarding seawater surface temperature (SST) and toxic algal abundance (TAA) were investigated to better understand the separated or combined effect on mussels during the uptake and elimination period.…”

Section: Discussionmentioning

confidence: 99%

Combined Effects of Temperature and Toxic Algal Abundance on Paralytic Shellfish Toxic Accumulation, Tissue Distribution and Elimination Dynamics in Mussels Mytilus coruscus

Tang

Zhang

Wang

et al. 2021

Toxins

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This study assessed the impact of increasing seawater surface temperature (SST) and toxic algal abundance (TAA) on the accumulation, tissue distribution and elimination dynamics of paralytic shellfish toxins (PSTs) in mussels. Mytilus coruscus were fed with the PSTs-producing dinoflagellate A. catenella under four simulated environment conditions. The maximum PSTs concentration was determined to be 3548 µg STX eq.kg−1, which was four times higher than the EU regulatory limit. The increasing SST caused a significant decline in PSTs levels in mussels with rapid elimination rates, whereas high TAA increased the PSTs concentration. As a result, the PSTs toxicity levels decreased under the combined condition. Additionally, toxin burdens were assessed within shellfish tissues, with the highest levels quantified in the hepatopancreas. It is noteworthy that the toxin burden shifted towards the mantle from gill, muscle and gonad at the 17th day. Moreover, variability of PSTs was measured, and was associated with changes in each environmental factor. Hence, this study primarily illustrates the combined effects of SST and TAA on PSTs toxicity, showing that increasing environmental temperature is of benefit to lower PSTs toxicity with rapid elimination rates.

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“…− into H 2 O 2 , which could be detoxi ed by CAT (Liu et al, 2020b). These two enzymes (SOD and CAT) constitute the antioxidant enzyme system to jointly combat oxidative stress.…”

Section: Sod Could Transform Omentioning

confidence: 99%

Toxicity Evaluation of Chlorpyrifos Metabolite 3,5,6-trichloro-2-pyridinol to Eisenia fetida in Different Soils

Hou¹,

Yang²,

Zhu³

et al. 2021

Preprint

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The present study utilized a biomarker response method to evaluate the effect of 3,5,6-trichloro-2-pyridinol (TCP) in artificial and natural soils on Eisenia fetida after 7, 14, 28, 42 and 56 days exposure. Biomarker responses were standardized to calculate the Integrated Biomarker Response (IBR) index. The influence of soil type on TCP toxicity was assessed. Results indicated that TCP induced excessive reactive oxygen species, caused oxidative stress, DNA damage to earthworm, which is similar to its parent chemical chlorpyrifos. The IBR index of three enzymes activities showed that TCP induced the enzymes activities of earthworm in red clay was stronger than the other three soils. Specifically, chlorpyrifos exposure group showed a lower toxicity than TCP exposure group after 28 days exposure but a higher toxicity than TCP exposure group after 56 days exposure. Despite the deficiencies of this study, the above information is of great significance for assessing the risk of chlorpyrifos and its metabolite TCP pollution in soil ecosystems.

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Antioxidant responses of triangle sail mussel Hyriopsis cumingii exposed to harmful algae Microcystis aeruginosa and high pH

Cited by 40 publications

References 43 publications

Effects of Acute Ammonia Stress on Antioxidant Responses, Histopathology and Ammonia Detoxification Metabolism in Triangle Sail Mussels (Hyriopsis cumingii)

Effects of Acute Ammonia Stress on Antioxidant Responses, Histopathology and Ammonia Detoxification Metabolism in Triangle Sail Mussels (Hyriopsis cumingii)

Combined Effects of Temperature and Toxic Algal Abundance on Paralytic Shellfish Toxic Accumulation, Tissue Distribution and Elimination Dynamics in Mussels Mytilus coruscus

Toxicity Evaluation of Chlorpyrifos Metabolite 3,5,6-trichloro-2-pyridinol to Eisenia fetida in Different Soils

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