Antioxidant response modulated by copper in healthy or parasitized carp (Cyprinus carpio L.) by Ptychobothrium sp. (Cestoda)

Dautremepuits, Claire; Betoulle, Stéphane; Vernet, Guy

doi:10.1016/s0304-4165(02)00328-8

Cited by 55 publications

(24 citation statements)

References 29 publications

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“…For example, expression of Tigriopus japonicus and Takifugu obscurus GSTs were signifi cantly induced by Cd and Cu exposure (Lee et al, 2007(Lee et al, , 2008Kim et al, 2010 (Bryan and Hummerstone, 1971). A signifi cant inhibition of GST activity was observed in Tubifex tubifex and Cyprinus carpio after exposure to 50-250 μg/L of Cu (Dautrememepuits et al, 2002;Mosleh et al, 2005). The expression of VpGSTS in Cd-exposed samples was much higher (12.5-fold) than that in Cu-exposed samples (3.5-fold), indicating that VpGSTS was more sensitive to Cd than to Cu.…”

Section: Discussionmentioning

confidence: 98%

Molecular cloning and differential expression patterns of sigma and omega glutathione S-transferases from Venerupis philippinarum to heavy metals and benzo[a]pyrene exposure

Zhang

Liu

et al. 2011

Chin. J. Ocean. Limnol.

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Glutathione S-transferases (GSTs) are a class of enzymes that facilitate the detoxifi cation of xenobiotics, and also play important roles in antioxidant defense. We identifi ed two glutathione S-transferase isoforms (VpGSTS, sigma GST; VpGSTO, omega GST) from Venerupis philippinarum by RACE approaches. The open reading frames of VpGSTS and VpGSTO were of 612 bp and 729 bp, encoding 203 and 242 amino acids with an estimated molecular mass of 22.88 and 27.94 kDa, respectively. The expression profi les of VpGSTS and VpGSTO responded to heavy metals and benzo[a]pyrene (B[a]P) exposure were investigated by quantitative real-time RT-PCR. The expression of VpGSTS and VpGSTO were both rapidly up-regulated, however, they showed differential expression patterns to different toxicants. Cd displayed stronger induction of VpGSTS expression with an approximately 12-fold increase than that of VpGSTO with a maximum 6.4-fold rise. Cu exposure resulted in similar expression patterns for both VpGSTS and VpGSTO. For B[a]P exposure, the maximum induction of VpGSTO was approximately two times higher than that of VpGSTS. Altogether, these fi ndings implied the involvement of VpGSTS and VpGSTO in host antioxidant responses, and highlighted their potential as a biomarker to Cd and B[a]P exposure.

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Section: Discussionmentioning

confidence: 98%

Molecular cloning and differential expression patterns of sigma and omega glutathione S-transferases from Venerupis philippinarum to heavy metals and benzo[a]pyrene exposure

Zhang

Liu

et al. 2011

Chin. J. Ocean. Limnol.

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“…Carp infected with the intestinal cestode Ptychobothrium sp. displayed an increased antioxidant response compared to uninfected fish as measured by activities of the enzymes catalase and glutathione reductase in liver and glutathione s-transferase in both liver and kidney (Dautremepuits et al 2002(Dautremepuits et al , 2003. The authors attributed this response to the increased metabolic activity of infected fish.…”

Section: Discussionmentioning

confidence: 99%

“…An increased enzyme antioxidant response was observed in carp Cyprinus carpio parasitized by the cestode Ptychobothrium sp. compared to healthy fish, indicating that some components of the fish antioxidant system can be modulated (Dautremepuits et al 2002(Dautremepuits et al , 2003. Belló et al (2000) demonstrated an increased tert-butyl hydroperoxideinitiated chemiluminescence, a measure of lipid peroxidation, in the muscle of fish infected with metacercariae of the trematode Clinostomum detruncatum.…”

Section: Introductionmentioning

confidence: 99%

Joint effects of parasitism and pollution on oxidative stress biomarkers in yellow perch Perca flavescens

Marcogliese¹,

Brambilla²,

Gagné³

et al. 2005

Dis. Aquat. Org.

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Yellow perch Perca flavescens were collected from a contaminated site and a reference site in the St. Lawrence River, Quebec, Canada. Fish were assessed for oxidative stress (lipid peroxidation and reduced glutathione levels) and parasitism by the nematode Raphidascaris acus and metacercariae of the digenean Apophallus brevis. Lipid peroxidation is not only considered a measure of oxidative stress, but of stress in general, and thus serves as an indicator of fish health. Fish from the contaminated site exhibited higher levels of lipid peroxidation than those from the reference site, independent of parasitic infections. However, fish infected with R. acus at the contaminated site tended to have higher levels of lipid peroxidation than uninfected fish at the same site, whereas no difference was observed between infected and uninfected fish at the reference site. Yellow perch infected with >10 metacercariae of A. brevis expressed higher levels of lipid peroxidation than those infected with <10 metacercariae at both the contaminated and the reference sites. No differences were found in levels of reduced glutathione in liver or muscle in relation to site or either parasite species. Results support the use of lipid peroxidation as a biomarker of water contamination. They further suggest that lipid peroxidation may be used as a biomarker of pathological effects caused by parasitism. Most importantly, results demonstrate that contaminants and parasites occurring together exacerbate oxidative stress in fish, suggesting that parasitized fish in polluted environments are in a poorer state of health than uninfected fish.

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“…when compared with healthy fish. This antioxidant response could contribute to neutralize the oxidative stress normally induced by parasitism (Dautremepuits et al 2002(Dautremepuits et al , 2003.…”

Section: Discussionmentioning

confidence: 99%

Oxidative stress in the gill tissues of goldfishes (Carassius auratus) parasitized by Dactylogyrus spp

Mozhdeganloo

Heidarpour

2013

J Parasit Dis

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The aim of this study was to investigate the status of oxidative stress in the gill tissues of goldfishes (Carassius auratus) parasitized by Dactylogyrus spp. We therefore compared the concentrations of malondialdehyde (MDA) and total thiol groups in the gill tissues of parasitized and non-parasitized goldfishes. 15 goldfishes parasitized by Dactylogyrus spp. along with 15 nonparasitized goldfishes were selected for the study. A significant increase in MDA concentration (P \ 0.01) and a significant decrease in total thiol groups in the parasitized group, were observed when compared to the non-parasitized group. This is the first study which evaluates the effect of Dactylogyrus spp. on the oxidative stress status of goldfish. The results of the present study revealed that parasitized goldfishes showed more severe oxidative stress and lipid peroxidation than non-parasitized fishes and enhanced lipid peroxidation may be linked to gill damage in goldfishes parasitized by Dactylogyrus spp.

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Antioxidant response modulated by copper in healthy or parasitized carp (Cyprinus carpio L.) by Ptychobothrium sp. (Cestoda)

Cited by 55 publications

References 29 publications

Molecular cloning and differential expression patterns of sigma and omega glutathione S-transferases from Venerupis philippinarum to heavy metals and benzo[a]pyrene exposure

Molecular cloning and differential expression patterns of sigma and omega glutathione S-transferases from Venerupis philippinarum to heavy metals and benzo[a]pyrene exposure

Joint effects of parasitism and pollution on oxidative stress biomarkers in yellow perch Perca flavescens

Oxidative stress in the gill tissues of goldfishes (Carassius auratus) parasitized by Dactylogyrus spp

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