Antioxidant Constituents from the Bark of Aglaia eximia (Meliaceae)

Sianturi, Julinton; Farabi, Kindi; Mayanti, Tri; Harneti, Desi; Darwati, Darwati; Supratman, Unang; Awang, Khalijah; Hayashi, Hideo

doi:10.7454/mss.v20i1.5655

Cited by 10 publications

(10 citation statements)

References 15 publications

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“…The HMBC spectrum shows correlations between H-1′′ at δ H 5.45 (1H, d, J = 7.75 Hz) with C-3 (δ C 133.2 ppm), which indicate that the sugar group was attached at C-3 of flavonoid structure. Comparing the NMR data of 5 (Table 2) with the literature data [15], compound 5 was identified as kaempferol-3-O-β-D-glucopyranoside.…”

Section: Compoundmentioning

confidence: 96%

“…Among the isolated compounds, compound 2 showed the strongest activity with an IC 50 value of 6.94 ± 0.03 µg/mL. Previous structure-activity studies of flavonoids have pointed to the importance of the number and location of OH groups, which could be more important for antiradical efficacy [15]. The glycoside derivatives of compound 4-6 showed weaker antioxidant activity than the nonglycoside derivatives, which suggests that sugar moiety can decrease antioxidant activity only in flavonoid derivatives.…”

Section: Compoundmentioning

confidence: 97%

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Flavonoid Compounds from Krokot Herb (Lygodium microphyllum) and their Antioxidant Activity against DPPH

et al. 2018

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Six flavonoid compounds, kaempferol (1), quercetin (2), acacetin (3), quercetin-3-O--D-glucopyranoside (4), kaempferol-3-O--D-glucopyranoside (5), and isorhamnetin-3-O--D-glucopyranoside ( 6), were isolated from the methanol extract of the Lygodium microphyllum herb. The chemical structures of compounds 1-6 were identified on the basis of spectroscopic evidence and comparison with previously reported spectral data. Compounds 1-6 were isolated for first time from this plant. Their antioxidant activity against DPPH (2,2-Diphenyl-1-picrylhydrazyl) was evaluated. Among the compounds, quercetin (2) showed high antioxidant activity with IC 50 values of 6.94 ± 0.03 g/mL.

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Section: Compoundmentioning

confidence: 96%

Section: Compoundmentioning

confidence: 97%

Flavonoid Compounds from Krokot Herb (Lygodium microphyllum) and their Antioxidant Activity against DPPH

et al. 2018

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“…The extensive isolation and identification of compounds from M. delavayi, Lin et al [66] reported new limonoid compounds, mulavanins A-E (30-34) together with three known limonoids, i.e. mombasol (35), 14,15β-epoxyprieurianin (36) and nymania 3 (37). It was reported that tigloyl unit appears to be attached on C-12 of 30-34.…”

Section: Limonoidmentioning

confidence: 99%

“…Meliaceae is well known as a source of diverse natural compounds with interesting biological activity. Some compounds including sesquiterpenoids [2][3][4][5][6][7], triterpenoids [8][9][10][11][12][13][14][15][16][17][18], diterpenoids [19][20][21], steroids [22][23][24][25], limonoids [26][27], alkaloids [28][29], lignan [30][31][32], flavaglines [33][34][35], and flavonoids [36][37] have been successively extracted from this family. Those isolated compounds showed interesting biological activities including cytotoxic [38][39][40][41], insecticidal [42][43], antimycobacterial [6], antifungal [44][45], antiinflammatory [9,[46]…”

Section: ■ Introductionmentioning

confidence: 99%

Phytochemistry and Pharmacology of <i>Munronia</i> Genus (Meliaceae)

Farabi

Supratman

2021

Indones. J. Chem.

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Munronia is a genus in the Meliaceae family, which consists of over 17 species that are distributed in the subtropical and tropical area of Asia, including southern China, Vietnam, Myanmar, Sri Lanka, India, Indonesia, and the Philippines. It is known that these plants contain valuable bioactive compounds. Since the first isolation of new stigmastane steroid was reported in 2003, researchers have been able to study the chemical composition of these plants, especially the largest secondary metabolite obtained, limonoid. About 97 compounds were isolated successfully and characterized. The reported compounds showed various biological activities, such as antifeedant, antimicrobial, antiangiogenic, cytotoxic against several cancer cell lines, inducing apoptosis, and anti-tobacco mosaic virus activities. Therefore, the results suggest that the use of this plant as a source of bioactive compounds is promising for the medicinal chemistry field.

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“…Some parts of the stem of the Aglaia plant have been used in traditional medicine for the treatment of skin diseases, fever, and wounds [3,4]. During the course of our continuous investigation for biologically active compounds from Indonesian Aglaia plants, we already isolated several bioactive compounds from A. smithii [5], A. eximia [6][7][8], A. argentea [9,10], and A. elliptica [11,12]. In further investigation on Aglaia plants that grow in Indonesia, we found that A. angustifolia has not been studied phytochemically previously.…”

Section: Introductionmentioning

confidence: 99%