Antioxidant capacity and antitumor activity of<i>Fructus Kochiae</i>extracts

Wang, J.; Yuan, Lin; Cheng, Bing; Li, W.; Xiao, Changlai; Wang, Y.; Liu, X.

doi:10.3920/qas2012.0218

Cited by 5 publications

(11 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Quantitative research on the content of saponins in Bassia species is limited to Kochiae fructus. Analysis of fruit from various regions of China using the HPLC-ELSD method showed that the saponin level ranges from 3.0 to 5.8% (Xia et al 2002a;Wang et al 2014a). In another study, qualitative gas-liquid chromatographic analysis (GLC) of methyl esters of triterpene sapogenins (methyl oleanolate) demonstrated that the sapogenin content ranges from 0.95 to 2.09% in a single seed of B. scoparia, reflecting the content of oleanolic acid-type saponins in plant material (Kernan et al 1973).…”

Section: Triterpene Saponins and Triterpenesmentioning

confidence: 99%

“…In addition to qualitative studies of the plant material, which reflect the quality of the product, investigations on momordin Ic content were also carried out on various extracts of Kochiae fructus. It can be seen that the amount of momordin Ic in the extract varies greatly depending on the extraction method (Choi et al 2014;Wang et al 2014a;Yoo et al 2017). For example, Wang et al (2014a), using the HPLC-ELSD method, found that the momordin content in the water extract (under infusion condition for 4 h at room temperature) was 2.88%, while in the 50% ethanol extract prepared under reflux conditions (4 h) it reached a higher value of 5.75%.…”

Section: Triterpene Saponins and Triterpenesmentioning

confidence: 99%

“…Most published studies on the cytotoxic activity of the Bassia genus concern B. scoparia species, while two articles describe the activity of B. indica (Abdel-Hamid et al 2017;Aboul-Enein et al 2012) and one B. muricata (Al-Barri et al 2021). Interestingly, only two of the reviewed papers defined, at least partially, the chemical content of the extracts studied (Cho et al 2019;Wang et al 2014a) and one paper provided a full chemical characterization of the essential oil of B. scoparia seeds which was the object of the study (Kianinodeh et al 2017). Most of the results indicate a rather weak cytotoxic potential of Bassia extracts.…”

Section: Cytotoxic Activitymentioning

confidence: 99%

See 2 more Smart Citations

Current knowledge on genus Bassia All.: a comprehensive review on traditional use, phytochemistry, pharmacological activity, and nonmedical applications

et al. 2023

View full text Add to dashboard Cite

Bassia All. is a genus from the Amaranthaceae family, which was created by merging selected species belonging to the former Bassia and Kochia genera with those classified to Chenolea, Londesia, Kirilowia and Panderia. The reorganised Bassia genus currently comprises around 20 species, which are annual herbs or perennial subshrubs native to Eurasia and Africa. Bassia plants are well known for their therapeutic applications in folk medicine and traditional medical systems, and they are also used for nonmedical purposes. Some members of this genus, such as Bassia scoparia (syn. Kochia scoparia) is of great medical importance and economic value. The plant is cultivated in some regions of Asia as a crop to collect Kochiae fructus, which is used for both curative and food purposes. Phytochemical studies carried out on Bassia species indicate that these plants synthesize metabolites belonging to different groups of compounds (e.g., triterpene saponins, sterols, flavonoids, fatty acids, lignanamides, alkaloids, organic acids). Some of the structures are rarely found in the plant kingdom. Biological activity studies carried out on Bassia plants revealed various effects exerted by extracts and isolated compounds, including anti-inflammatory, cytotoxic, antioxidant, antimicrobial, hypoglycemic, anti-obesity, etc. Modern research explained some of the mechanisms of action. This review covers literature from 1935 to 2022, and assembles and discusses data on phytochemistry, biological activity, as well as medical and nonmedical use of the representatives of the genus Bassia. In this review we present the current state of knowledge about the plants of the genus.

show abstract

Section: Triterpene Saponins and Triterpenesmentioning

confidence: 99%

Section: Triterpene Saponins and Triterpenesmentioning

confidence: 99%

Section: Cytotoxic Activitymentioning

confidence: 99%

See 1 more Smart Citation

Current knowledge on genus Bassia All.: a comprehensive review on traditional use, phytochemistry, pharmacological activity, and nonmedical applications

et al. 2023

View full text Add to dashboard Cite

show abstract

“…The present study indicates that the volatile oils of K. scoparia possess anticonvulsant activity against MES and PTZ induced convulsive models. The anticonvulsant activity of this volatile oil might be attributable to its antioxidant propensity (Wang et al, 2014) as well as chemical constituents like terpenes (Abdelaamed et al, 2013) and, flavonoids (Asl et al, 2007which are reported to possess anticonvulsant activity in some experimental seizure models such as MES and PTZ (Chauhan et al, 1988;Kasture et al, 2002). It is also found that many flavonoids could act as benzodiazepine-like molecules in the central nervous system and modulate GABA-generated chloride currents in animal models of anxiety, sedation and convulsion (Asl et al, 2007).…”

Section: Discussionmentioning

confidence: 99%

“…al., 1997), anticancer, dermatological (Jeon et. al., 2016), antioxidant (Wang et al, 2014), and antidiabetic effects (Yoshikawa et al, 1997). The seeds are used in traditional Chinese medicine to help regulate disorders, such as hyperlipidemia, hypertension, obesity and atherosclerosis.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Anticonvulsant Activity of Kochia Scoparia L. Schrad (Amaranthaceae) Volatile Oil

Imade¹,

Uchendu²,

Akhigbemen³

et al. 2021

njpr

View full text Add to dashboard Cite

Background: Epilepsy is one of the most common serious neurological disorders. Most antiepileptic or anticonvulsant drugs do not prevent or reverse the pathological process that underlies epilepsy, hence the continuous search for new therapeutic agents with minimal side effects and greater efficacy.Objective: The objectives of this study were to determine the acute toxicity profile and investigate the anticonvulsant activity of volatile oil of Kochia scoparia (Amaranthaceae ).Method: Volatile oil was extracted from fresh leaves of K. scoparia through hydrodistillation process, using a Clavenger-type apparatus. Acute toxicity testing was done using Lorke’s method. The anticonvulsant models used were pentylenetetrazol, strychnine and maximal electroshock. Albino mice were randomly divided into five groups (n=5). Group I (control group) was given 0.2 ml each of water orally while groups II, III and IV received 75, 150 and 300 mg/kg of the volatile oil. Group V received the standard drug solution; 30 mg/kg phenobarbitone for Maximal electroshock and 2 mg/kg diazepam for pentylenetetrazol and strychnine models. The onset of tonic leg extension, duration and protection from mortality were noted.Results: Sub acute toxicity test revealed that doses above 1000mg/kg of the volatile oil is toxic. Doses of 75, 150 and 300 mg/kg significantly (P<0.05) protected the mice against seizures with scores of 20, 20 and 40 % respectively in both Maximal electroshock and pentylenetetrazol induced convulsion models. No protection was offered in strychnine induced convulsion model; P > 0.05.Conclusion: The volatile oil of K. scoparia could be useful in the management of epilepsy.

show abstract

Physical properties and antioxidant capacity of chitosan/epigallocatechin-3-gallate films reinforced with nano-bacterial cellulose

Wang

Xie

et al. 2018

Carbohydrate Polymers

View full text Add to dashboard Cite

Antioxidant capacity and antitumor activity ofFructus Kochiaeextracts

Cited by 5 publications

References 40 publications

Current knowledge on genus Bassia All.: a comprehensive review on traditional use, phytochemistry, pharmacological activity, and nonmedical applications

Current knowledge on genus Bassia All.: a comprehensive review on traditional use, phytochemistry, pharmacological activity, and nonmedical applications

Evaluation of Anticonvulsant Activity of Kochia Scoparia L. Schrad (Amaranthaceae) Volatile Oil

Physical properties and antioxidant capacity of chitosan/epigallocatechin-3-gallate films reinforced with nano-bacterial cellulose

Contact Info

Product

Resources

About