Antioxidant and α-glucosidase activities of benzoic acid derivate from the bark of Myristica fatua Houtt

Megawati, Megawati; Darmawan, Ahmad; Fajriah, Sofa; Primahana, Gian; Dewi, Rizna Triana; Minarti, Minarti; Meiliawati, Lia

doi:10.1063/1.5011884

Cited by 5 publications

(2 citation statements)

References 27 publications

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“…Since those methods yield rapid, repeatable findings and only call for relatively standard equipment, they have been frequently employed to assess the antioxidant capabilities of plant extracts. The antioxidant activity (DPPH) [21] by [22] with little modification. The variation of concentration (100, 50, 25, 10 ppm) repeated three times, added with 0.5 mL of 1 mM DPPH in MeOH.…”

Section: Determination Of Antioxidant Activitiesmentioning

confidence: 99%

Volatile Compounds and Bioactivities of Non Polar Extracts of Horsfieldia macrothyrsa leaves and twigs

Megawati,

Darmawan,

Hudiyono

et al. 2024

E3S Web Conf.

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The purpose of this study is to ascertain the chemical composition of Horsfieldia macrothyrsa leaves and twigs by using Gas Chromatography/Mass Spectrometry (GC/MS) to extract the hexane (non-polar) fraction, which has antioxidant, antidiabetic, and anticancer properties against the MCF-7 breast cancer cell line. As per the findings, the primary constituents of this fraction were fatty acids and sesquiterpenes, with the other constituents being sesamin (13.32% twigs), palmitic acid (20.58% leaves), squalene (2.7% twigs), and linolenic acid (25.56% leaves). According to the antidiabetic activity test, the hexane fraction of H. macrothyrsa twigs exhibited an IC50 of 23.230 ± 0.22 μg/mL. In contrast, the antioxidant values of the leaves and twigs ranged from 50 μg/mL. The breast cancer cell line MCF-7 exhibited cytotoxic capability in an in vitro anticancer assay.

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Section: Determination Of Antioxidant Activitiesmentioning

confidence: 99%

Volatile Compounds and Bioactivities of Non Polar Extracts of Horsfieldia macrothyrsa leaves and twigs

Megawati,

Darmawan,

Hudiyono

et al. 2024

E3S Web Conf.

View full text Add to dashboard Cite

show abstract

“…NMR spectroscopic data for compounds 1-3 Note: a recorded in CDCl3, b 125 MHz, c 500 MHz, d recorded in MeOD, e,g 125 MHz, f,h 500 MHz, # δC of 4-hydroxy-3methoxybenzaldehyde[15] (in CDCl3 at 100MHz) and ## δC, ### δC of methyl 3,4-dihydroxybenzoate[16], 3,4dihydroxybenzoic acid[17] (in MeOD at 125 MHz).…”

mentioning

confidence: 99%