Antioxidant and hepatoprotective activity of ethanolic extract of leaves of Solidago microglossa containing polyphenolic compounds

Sabir, Syed Mubashar; Ahmad, Syed Dilnawaz; Hamid, Abdul; Khan, Muhammad Qayyum; Athayde, Margareth Linde; Santos, Danúbia Bonfanti; Boligon, Alexandra Augusti; Rocha, João Batista Teixeira da

doi:10.1016/j.foodchem.2011.09.026

Cited by 115 publications

(69 citation statements)

References 18 publications

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“…The phenolics and flavonoids in the extract were quantified by reverse phase chromatographic analysis by the method described by Sabir SM, et al [27] with slight modifications. Reverse phase chromatographic analysis was carried out under gradient conditions using C 18 column (4.6 mm´250 mm) packed with 5-mm diameter particles.…”

Section: Quantification Of Compounds By Hplc-dadmentioning

confidence: 99%

African eggplant (Solanum anguivi Lam.) fruit with bioactive polyphenolic compounds exerts in vitro antioxidant properties and inhibits Ca2+-induced mitochondrial swelling

Elekofehinti

Kamdem

Bolingon

et al. 2013

Asian Pacific Journal of Tropical Biomedicine

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Section: Quantification Of Compounds By Hplc-dadmentioning

confidence: 99%

African eggplant (Solanum anguivi Lam.) fruit with bioactive polyphenolic compounds exerts in vitro antioxidant properties and inhibits Ca2+-induced mitochondrial swelling

Elekofehinti

Kamdem

Bolingon

et al. 2013

Asian Pacific Journal of Tropical Biomedicine

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“…The extract (1,000 lg) exhibited 73.5 ± 4.66 and 69.24 ± 3.97 % of antioxidant and H 2 O 2 radical scavenging activity, respectively, which revealed that the leaves of P. serratifolia possess the anticancer activity and radical scavenging activity. Euphorbia neriifolia extract significantly restored the antioxidant enzyme level in the liver and exhibited significant dose-dependant protective effect against DENA-induced liver toxicity, which can be mainly attributed to the antioxidant property of the extract (Sabir et al 2012). AgNps synthesized using Alternanthera sessilis (Linn.)…”

Section: Resultsmentioning

confidence: 99%

Biosynthesis of silver nanoparticles from Premna serratifolia L. leaf and its anticancer activity in CCl4-induced hepato-cancerous Swiss albino mice

Paul¹,

Selvi²,

Karmegam³

2015

Appl Nanosci

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In this study, we report the biosynthesis of silver nanoparticles using the ethanolic leaf powder extract of Premna serratifolia L. and its anticancer activity in carbon tetra chloride (CCl 4 )-induced liver cancer in Swiss albino mice (Balb/c). The synthesized silver nanoparticles were characterized by SEM, FTIR and XRD analyses. The Debye-Scherrer equation was used to calculate particle size and the average size of silver nanoparticles synthesized from P. serratifolia leaf extract was 22.97 nm. The typical pattern revealed that the sample contained cubic structure of silver nanoparticles. FTIR analysis confirmed that the bioreduction of silver ions to silver nanoparticles is due to reduction by capping material of the plant extract. The silver nanoparticles of P. serratifolia leaf extract were effective in treating liver cancer in Swiss albino mice when compared with P. serratifolia leaf extract with isoleucine.

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“…Stock solutions of standards references were prepared in the HPLC mobile phase at a concentration range of 0.020 -0.200 mg/ml for quercetin, quercitrin isoquercitrin, kaempferol rutin, catechin and epicatechin; and 0.050 -0.250 mg/ml for chlorogenic, ellagic acid, caffeic and gallic acids. The limit of detection (LOD) and limit of quantification (LOQ) were calculated based on the standard deviation of the responses and the slope using three independent analytical curves, as defined by Sabir et al (2012 ) LOD and LOQ were calculated as 3.3 and 10 σ/S, respectively, where σ is the standard deviation of the response and S is the slope of the calibration curve.…”

Section: Quantification Of Compounds By Hplc-dadmentioning

confidence: 99%

In-vitro characterization and biological properties of polyphenols extract of ripe garden egg (Solanum gilo)

Emem¹,

Christiana²

2017

JEBAS

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KEYWORDS Solanum gilo Polyphenols Proximate HPLC/DAD analysis Feed source ABSTRACTThis study sought to investigate and compare the HPLC/DAD characterization, nutrient composition of ripe and unripe garden egg fruits to see its potentials for use in animal feed and in industrial processes. Analyses were carried out on Solanum gilo ripe (SGR) and Solanum gilo unripe (SGU) dried samples. Proximate analysis and minerals such as (Ca, Na, K, Mg, Zn) as well as some anti-nutritional factors (phytates, tannins) were carried out on the powdered samples. Polyphenols content were identified and quantified using HPLC-DAD. Total phenols, total flavonoids and vitamin C content was determined, while its antiradical assay was examined as typified 1,1-diphenyl-2 picrylhydrazyl [DPPH] and 2,2-Azinobis (3-ethylbenzo-thiazoline-6-sulfonate [ABTS]. Results of the study revealed an increased in fat and crude fibre content while a slight reduction was reported in protein content but no significant changes was reported in the total carbohydrate content. HPLC-DAD analysis showed that gallic acid was the most abundant phenolics present. There was increased in some of the flavonoids due to ripening such as Ellagic acid, Isoquercitrin, Quercetrin and Kaempferol. The total phenols, flavonoids increased in SGR, there was no change in DPPH scavenging ability while ABTS scavenging ability increased with the SGR. It can be concluded that ripe garden eggs which is usually discarded could be of use as an excellent livestock feed source/additives

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Antioxidant and hepatoprotective activity of ethanolic extract of leaves of Solidago microglossa containing polyphenolic compounds

Cited by 115 publications

References 18 publications

African eggplant (Solanum anguivi Lam.) fruit with bioactive polyphenolic compounds exerts in vitro antioxidant properties and inhibits Ca2+-induced mitochondrial swelling

African eggplant (Solanum anguivi Lam.) fruit with bioactive polyphenolic compounds exerts in vitro antioxidant properties and inhibits Ca2+-induced mitochondrial swelling

Biosynthesis of silver nanoparticles from Premna serratifolia L. leaf and its anticancer activity in CCl4-induced hepato-cancerous Swiss albino mice

In-vitro characterization and biological properties of polyphenols extract of ripe garden egg (Solanum gilo)

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