Antioxidant and cytotoxic activities of xanthones from Cudrania tricuspidata

Lee, Byong Won; Lee, Jin Hwan; Lee, Sung-Tae; Lee, Hyun Sun; Lee, Woo Song; Jeong, Tae‐Sook; Park, Ki Hun

doi:10.1016/j.bmcl.2005.08.099

Cited by 134 publications

(52 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These naturally occurring compounds and their synthetic analogs have demonstrated multiple pharmacological properties, such as anti-oxidant, antiinflammatory, anti-malarial and anti-cancer activities, etc. [4][5][6][7][8][9]. Xanthones may be viewed as flavone derivatives having three linear aromatic rings in which the phenyl group is fused with two aromatic rings, as shown in Fig.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of the Zn(II) and Cu(II) piperidinyl isoeuxanthone complexes: DNA-binding and cytotoxic activity

Wang

Shen

2009

European Journal of Medicinal Chemistry

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of the Zn(II) and Cu(II) piperidinyl isoeuxanthone complexes: DNA-binding and cytotoxic activity

Wang

Shen

2009

European Journal of Medicinal Chemistry

View full text Add to dashboard Cite

“…They possess various beneficial effects, including antitumor, anticancer, antioxidant, anti-inflammatory, anti-atherosclerotic, and anti-diabetic (3)(4)(5)(6). In particular, these components are of great interest in the food industry because of their nutritional values (7).…”

Section: Introductionmentioning

confidence: 99%

Determination of Phytochemical Contents and Biological Activities from the Fruits of Elaeagnus multiflora

Lee¹,

Seo²,

Cho

2011

JFN

View full text Add to dashboard Cite

The purpose of this study was to investigate the phytochemical contents and biological activities, including α-glucosidase inhibitory activity and antioxidant activity, from the fruits of Elaeagnus multiflora using different solvent systems. The 50% ethanol extract of this species showed the most potent α-glucosidase inibitory activity (88.5%) at a concentration of 1 mg/mL. Moreover, this extract also displayed the strongest antioxidant activity in each assay, showing 96.3% in DPPH scavenging activity, 98.2% in ABTS scavenging activity, and 2.5% in reducing power. The highest total phytochemical contents, including flavan-3-ols, phenolic acids, and flavonoids, were observed in the 50% ethanol extract. Interestingly, flavan-3-ols (3.150 mg/g) were detected at a significantly higher total content than those of phenolic acids (0.380 mg/g) and flavonoids (not detected). Additionally, the contents of individual phytochemicals showed remarkable differences, especially the epicatechin gallate (2.008 mg/g) and gallic acid (0.099 mg/g), which were the predominant constituents of each phytochemical type. Therefore, our results suggest that the 50% ethanol extract of E. multiflora fruits has strong biological activities, which are correlated with high phytochemical contents.

show abstract

“…Xanthones in the extract could transfer labile H-atoms to radicals. Lee et al 21 investigated the antioxidant activity of the xanthones of Cudrania tricuspidata. It was found that a xanthones of C. tricuspidata (cudraxanthone D), which contain a dihydroxyl group in the B-ring, exhibited strong radical scavenging activities.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Kosem¹,

Han²,

Moongkarndi³

2007

ScienceAsia

View full text Add to dashboard Cite

Garcinia mangostana has been documented in Thai traditional medicine in various aspects. Although many benefits have been claimed, few scientific reports are available in the literature. In the present study, the methanolic extract from G. mangostana hulls (GME) was assessed for antioxidant and cytoprotective activities. The results showed that GME contained phenolic compounds and possessed reducing power as well as Fe 2+ chelating activity. The antioxidant properties were determined by scavenging DPPH, nitric oxide and lipid radicals in dose-dependent manners. In particular, the powerful scavenging activities were found against hydroxyl and superoxide radicals when investigated using ESR spectrometry. GME also enhanced the cell survival by decreasing the oxidative damage in ECV304 endothelial cells after H 2 O 2 exposure. These data indicated that GME played a pivotal role on the antioxidant and chemopreventive activities via a reducing mechanism and inhibition of intracellular oxidative stress, respectively.

show abstract

Antioxidant and cytotoxic activities of xanthones from Cudrania tricuspidata

Cited by 134 publications

References 22 publications

Synthesis and characterization of the Zn(II) and Cu(II) piperidinyl isoeuxanthone complexes: DNA-binding and cytotoxic activity

Synthesis and characterization of the Zn(II) and Cu(II) piperidinyl isoeuxanthone complexes: DNA-binding and cytotoxic activity

Determination of Phytochemical Contents and Biological Activities from the Fruits of Elaeagnus multiflora

Untitled

Contact Info

Product

Resources

About