Determination of Phytochemical Contents and Biological Activities from the Fruits of Elaeagnus multiflora

Abstract

The purpose of this study was to investigate the phytochemical contents and biological activities, including α-glucosidase inhibitory activity and antioxidant activity, from the fruits of Elaeagnus multiflora using different solvent systems. The 50% ethanol extract of this species showed the most potent α-glucosidase inibitory activity (88.5%) at a concentration of 1 mg/mL. Moreover, this extract also displayed the strongest antioxidant activity in each assay, showing 96.3% in DPPH scavenging activity, 98.2% in ABTS scavenging activity, and 2.5% in reducing power. The highest total phytochemical contents, including flavan-3-ols, phenolic acids, and flavonoids, were observed in the 50% ethanol extract. Interestingly, flavan-3-ols (3.150 mg/g) were detected at a significantly higher total content than those of phenolic acids (0.380 mg/g) and flavonoids (not detected). Additionally, the contents of individual phytochemicals showed remarkable differences, especially the epicatechin gallate (2.008 mg/g) and gallic acid (0.099 mg/g), which were the predominant constituents of each phytochemical type. Therefore, our results suggest that the 50% ethanol extract of E. multiflora fruits has strong biological activities, which are correlated with high phytochemical contents.

Phylogenetic Relationships in Korean Elaeagnus L. Based on nrDNA ITS Sequences

“…Additionally, many species are commonly used in traditional medicine to treat symptoms such as cough, diarrhea, itching and foul sores. Phytochemical studies have shown various medicinal properties of this genus, including antioxidant and anti-tumor (Kim et al, 2007;Lee and Seo, 2011).…”

Distribution of Polyphenolic and Isoprenoid Compounds and Biological Activity Differences between in the Fruit Skin + Pulp, Seeds, and Leaves of New Biotypes of Elaeagnusmultiflora Thunb

“…This carotenoid is responsible for their red color and has been extensively studied as one of the major dietary carotenoids for humans [2]. Lee et al [3] demonstrated that in addition to chlorophylls, the leaves of cherry silverberry have high contents of sugars, fatty acids, and phytosterols. However, the polyphenolic profile of cherry silverberry fruits has not yet been thoroughly recognized.…”

Extracts of Elaeagnus multiflora Thunb. fruit fermented by lactic acid bacteria inhibit SW480 human colon adenocarcinoma via induction of cell cycle arrest and suppression of metastatic potential

“…The genus was considered invasive in many parts of the world until the nutritional and medicinal properties of several species have been explored in the past years (Patel, 2015). In particular, the species Elaeagnus multiflora Thunb., also known as cherry silverberry (CS), has been investigated for the phytochemical content (Lee, Seo, & Cho, 2011); antioxidant and antiproliferative activities (Oh & Lee, 2008); anti-inflammatory and whitening effects (Lee et al, 2007); and anticancer properties (Lee, Lee, & Park, 2010) of its different solvent extracts. Because of the fruit's promising potential as a functional food, it is important to apply processing techniques that would not only lengthen its shelf-life, but also enhance its biological activities.…”