Antioxidant and cardioprotective effects of Danshensu (3-(3, 4-dihydroxyphenyl)-2-hydroxy-propanoic acid from Salvia miltiorrhiza) on isoproterenol-induced myocardial hypertrophy in rats

Antihypertensive and cardioprotective effects of theLagenaria sicerariafruit inNG-nitro-L-arginine methyl ester (L-NAME) induced hypertensive rats

“…(Aquifoliaceae) (Schinella et al, 2009), Salvia miltiorrhiza var. miltiorrhiza (Lamiaceae) (Tang et al, 2011) may be due to antioxidant activity. In this context, the antioxidant property of orientin and isoorentin may contribute to cardioprotecive effect of LS observed in the present study.…”

Bioactive phytochemicals from shoots and roots of Salvia species

“…Compounds 186 and salvianolic acid B (198) isolated from S. miltiorrhiza showed higher DPPH free radical and 2,2 0 -azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity than that of L-ascorbic acid (Table 6) (Sun et al 2009). Compound 182 namely 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid, isolated from S. miltiorrhiza can increase the serum activity of superoxide dismutase in a dose-dependent manner in rats (Tang et al 2011).…”

Protective effect of a polysaccharide from Salvia miltiorrhiza on isoproterenol (ISO)-induced myocardial injury in rats

“…Recently, there has been a growing interest in developing phytopharmaceuticals from medicinal plants to cope with this condition, owing to their non-addictive and non-toxic nature. Some plant products have been found to be more effective in the management of MI throught augmentation of myocardial antixoidants, such as Danshensu (Tang et al, 2011), Rhodobryum roseum extract (Hu et al, 2009), Cladosiphon okamuranus fucoidan (Thomes et al, 2010), 20(S)-panaxadiol (Wang, Meng, Zhang, Bi, & Jiang, 2010), and so on. Salvia miltiorrhiza, commonly known as DanShen, is one of the most famous traditional Chinese herbal medicines used for the treatment of ischemic cardiovascular diseases, containing phenolic compounds and potent antioxidant moieties (Ji, Tan, Zhu, Linz, & Zhu, 2003;Ji et al, 2004;Sun et al, 2005).…”