Antioxidant and antiulcerogenic activities of Opuntia ficus indica f. inermis root extract in rats

Phytochemical, antioxidant and protective effect of Rhus tripartitum root bark extract against ethanol-induced ulcer in rats

“…The microscopic study of the histological sections shows the erosion of the gastric epithelial cells, the widening of the inter-glandular spaces and the infiltration of the neutrophiles in the ulcerated zones. These results confirmed our previous finding (Alimi et al 2010). In normal conditions gastric cells possess a powerful antioxidant defense system, including SOD, CAT and GSH-Px which play a protective role against xenobiotics (Sehirli et al 2008).…”

“…Phytochemical studies demonstrated that RTE contain high phenolic content in comparison with the phenolics level detected in Opuntia ficus indica f. inermis root extract, known for their antiulcerogenic effects (Alimi et al 2010). In addition higher tannin content has been detected in RTE when compared with the level detected in Rhus oxyacantha fresh root bark extract (Tebourbi et al 2006).…”

“…The infection with Helicobacter pylori and the uses of non-steroid anti-inflammatory drugs (NSAIDs) are identified as promoters of gastric ulcer development (O'Malley 2003). In addition, we have previously demonstrated that acute ethanol consumption results in gastric ulcer evidenced by acute hemorrhagic lesions, mucosal edema, epithelial exfoliation, inflammatory cell infiltration and alterations in the cell redox state (Alimi et al 2010(Alimi et al , 2011. A number of products have been used for the treatment of gastric ulcers such as antihistaminics, proton pump inhibitors or antacids, but most of these drugs produce several adverse reactions (Singh et al 2008).…”

“…The phytochemical studies of RTE revealed the presence of high amount of phenolic contents (122.88 ± 0.51 mg GAE/g) when compared with the phenolics contents detected in the root extract of Opuntia ficus indica f. inermis (57.56 ± 0.51 mg GAE/g), demonstrated to have an antiulcerogenic effects (Alimi et al 2010). On the other hand, the chemical studies of RTE show a substantial content of flavonoids (9.12 ± 0.22 mg RE/g) when compared with the aqueous root extract of Rhus pentaphyllum (Ben Mansour et al 2011).…”

Evaluation of Antioxidant Activity and Phenolic Composition of <i>Opuntia ficus-indica</i> Cladodes Collected from Moroccan Settat Region

“…The previous studies show that most of the phenolic compounds were in the ethanol extract while tannins were mainly found in acetone extract, which were similar to the results in this study. Alimi et al [35] reported 57.65 mg of polyphenol per g of methanol extract of roots of Opuntia ficus-indica f. inermis. According to Medina-Torres et al [34], the total flavonoid content in Nopal cactus (O. ficus-indica) cladodes ranged from 10.80 ± 0.33 to 23.40±1.83 mg g -1 .…”