Antioxidant and antimutagenic activities of bark extract of Terminalia arjuna

Evaluation of in vitro aldose reductase inhibitory potential of different fraction of Hybanthus enneaspermus Linn F. Muell

“…So aldose reductase inhibition in the early onset of the secondary complication in the diabetic mellitus will be beneficial, as ethyl acetate fraction showed good inhibitory activity against aldose reductase so it can be potentially used to treat diabetic complication in the early stage. The inhibitory effects of plant phytochemicals, including polyphenols which are currently regarded as natural antioxidants, and their antioxidant activities are important for human health, against carbohydrate hydrolyzing enzymes which contribute to the lowering of blood glucose in diabetics and are capable of reducing oxidative stress by scavenging reactive oxygen species and preventing cell damage [20,21] . In addition, some flavonoids and polyphenols as well as sugar derivatives are found to be effective in inhibiting 毩-glucosidase and aldose reductase enzyme [22] .…”

Antidiabetic and in vitro antioxidant potential of Hybanthus enneaspermus (Linn) F. Muell in streptozotocin–induced diabetic rats

“…Polyphenolic scavenging action is mainly due to their hydroxyl groups. They are very important plant constituents which can protect body from different type of oxidative stress [36][37][38][39] . Flavones glycosides have also been reported as strong antioxidants and potent hypoglycemic agents.…”

Cataract: A major secondary diabetic complication

“…Many studies have done to identify the natural or synthetic compound that inhibit aldose reductase and flavonoids are found to most potent aldose reductase inhibitors (Constantino et al, 1999). Plant phytochemicals including polyphenols, which are currently regarded as natural antioxidant they are important for human health against various types of enzymes, which reduces the blood glucose level in diabetes, and are capable of reducing the oxidative stress by scavenging the free radicals and prevention cell damage (Vishvanath et al, 2010;Girija et al, 2011).…”