Antioxidant and Antimicrobial Activity of Algal and Cyanobacterial Extracts: An In Vitro Study

Frazzini, Sara; Scaglia, Elena; Dell’Anno, Matteo; Reggi, Serena; Panseri, Sara; Giromini, Carlotta; Lanzoni, Davide; Rossi, C.A. Sgoifo; Rossi, Luciana

doi:10.3390/antiox11050992

Cited by 36 publications

(20 citation statements)

References 76 publications

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“…В исследованиях ведущих ученых также была показана антимикробная активность разных экстрактов из биомассы С. vulgaris [21,22]. В исследовании [21] водный экстракт C. vulgaris показал антибактериальную активность, как в отношении грамотрицательных (E. coli), так и грамположительных (S. aureus) бактерий.…”

Section: таблица 1 результаты анализа антиоксидантной активности бк л...unclassified

“…Наиболее высокой антимикробной активностью в отношении E. coli обладала белковая фракция, полученная методом ТХУ (TCA) из водного экстракта, с минимальной зоной ингибирования 32,5-65 мг/мл [21]. В других исследованиях экстракты зеленых одноклеточных водорослей показали выраженную антагонистическую активность в отношении многочисленных условно-патогенных и патогенных бактерий [21][22][23][24].…”

Section: таблица 1 результаты анализа антиоксидантной активности бк л...unclassified

“…A. platensis показала антибактериальный потенциал против всех исследованных микроорганизмов. Значения зон ингибирования тестируемых штаммов варьировалось от 0.9 до 1.3 см [22].…”

Section: таблица 1 результаты анализа антиоксидантной активности бк л...unclassified

“…Цианобактерии (синезеленые водоросли) обладают уникальными биохимическими свойствами и являются потенциальным источником биологически активных вторичных метаболитов. Микроводоросли продуцируют внутриклеточные и внеклеточные метаболиты с пребиотической, антибактериальной, антиоксидантной, противогрибковой и противовирусной активностью [22,35]. Спирулина является идеальным биоресурсом благодаря своему богатству белком, фикоцианином, незаменимыми аминокислотами, полисахаридами, каротиноидами, минералами, витаминами и незаменимыми жирными кислотами [22,35].…”

Section: таблица 1 результаты анализа антиоксидантной активности бк л...unclassified

“…Микроводоросли продуцируют внутриклеточные и внеклеточные метаболиты с пребиотической, антибактериальной, антиоксидантной, противогрибковой и противовирусной активностью [22,35]. Спирулина является идеальным биоресурсом благодаря своему богатству белком, фикоцианином, незаменимыми аминокислотами, полисахаридами, каротиноидами, минералами, витаминами и незаменимыми жирными кислотами [22,35]. Она также богата витаминами, минералами, углеводами и гамма-линоленовой кислотой.…”

Section: таблица 1 результаты анализа антиоксидантной активности бк л...unclassified

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In vitro study of biologically active properties of complexes isolated from biomass of microscopic algae

et al. 2022

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Microalgae are rich in biologically active substances: proteins, carbohydrates, lipids, polyunsaturated fatty acids, vitamins, pigments, phycobiliproteins, enzymes, which are able to provide antioxidant, immunostimulating, antibacterial, antiviral, antitumor, antihypertensive, regenerative and neuroprotective effects on a body. The aim of this study is to run in vitro study of the antioxidant, antibacterial, fungicidal, antihypertensive and prebiotic properties of protein concentrate (PC), lipid-pigment complex (LPC) and carbohydrate-mineral complexes (CMC) obtained from the biomass of microscopic algae. To determine in vitro the antioxidant, antibacterial, fungicidal, antihypertensive and prebiotic properties of protein concentrates, lipid-pigment complexes and carbohydratemineral complexes obtained from the biomass of microscopic algae, the following methods were used: method of diffusion (on a solid nutritional medium); optical density method (in a liquid nutritional medium); the method for determining the antioxidant activity of the researched samples by their ability to restore free radicals; the method of inhibition of the angiotensin-converting enzyme. It was shown in this study that among the studied samples the carbohydrate-mineral complex provided the most pronounced antioxidant effect. It was found that both protein concentrates, and lipid-pigment complexes and carbohydrate-mineral complexes feature antibacterial and fungicidal properties. It was proven that among the studied samples the carbohydrate-mineral complex provided the least pronounced antihypertensive effect. It was found that the lipid-pigment complexes and carbohydrate-mineral complexes practically have no prebiotic properties. The biological activity (antimicrobial, fungicidal, antioxidant and prebiotic activities), as well as the antihypertensive properties, were confirmed in the protein concentrates, lipid-pigment complexes and carbohydrate-mineral complexes obtained from the biomass of microscopic algae (Chlorella vulgaris, Arthrospira platensis, Nostoc sp., Dunaliella salina, Pleurochrysis carterae). All these factors open up promising prospects for the practical application of protein concentrates, as well as lipid-pigment complexes and carbohydrate-mineral complexes.

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Section: таблица 1 результаты анализа антиоксидантной активности бк л...unclassified

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In vitro study of biologically active properties of complexes isolated from biomass of microscopic algae

et al. 2022

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Nutritional values, antioxidant, and cytotoxic activities of selected edible marine macroalgae: a comparative study

El-Rafie,

Hammam,

Ahmed

2024

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The objective of this study is to assess the chemical composition, nutritional values, and bioactivities of four macroalgae from the Egyptian Red Sea coasts using standard methods. Of these, three Rhodophyceae species, Digenea simplex (D. simplex), Laurencia papillosa (L. papillosa), and Galaxaura oblongata (G. oblongata), and one Phyaeophyceae species, Turbinaria decurrens (T. decurrens), were selected. The results of proximate and chemical composition analyses based on the algal dry weight (DW) showed that carbohydrate content was the highest, ranging from 32.47 ± 1.03% to 45.5 ± 1.23%. Other algal constituents, including ash, protein, moisture, sulfate, lipid, phenolics, and flavonoids, have contents that depend on the algal species. Besides, HPLC analysis revealed that each algal extract contained varying amounts of nine phenolic acids. Atomic absorption spectrometry, the HPLC-Pico-Tag method, the ion chromatography technique, and GC/MS analyses were used to determine the chemical profiles of the elemental, amino acid, halide, and fatty acid of each algal extract. Bioactivities revealed that both the •DPPH and ABTS assays showed that all the algae studied had a significant ability to scavenge free radicals in a dosage-dependent way. They also had strong selective cytotoxic activity against HEPG-2 and HCT-116 cell lines, but only weak activity against MCF-7 and A549 cell lines. Finally, our findings suggested that the selected algae might be efficiently used as nutraceuticals and functional foods, indicating an increase in their proliferation.

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Antimicrobial therapeutics isolated from algal source: retrospect and prospect

et al. 2022

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In the last few decades, attention on new natural antimicrobial compounds has arisen due to a change in consumer preferences and the increase in the number of resistant microorganisms. Algae are defined as photosynthetic organisms that demonstrate a wide range of adaptability to adverse environmental conditions like temperature extremes, photo-oxidation, high or low salinity, and osmotic stress. Algae are primarily known to produce large amounts of secondary metabolite against various kinds of pathogenic microbes. Among these algae, micro and microalgae of river, lake, and algae of oceanic origin have been reported to have antimicrobial activity against the bacteria and fungi of pathogenic nature. Various polar and non- polar extracts of micro- and macro algae have been used for the suppression of these pathogenic fungi. Apart from these, certain algal derivatives have also been isolated from these having antibacterial and antifungal potential. Among the bioactive molecules of algae, polysaccharides, sulphated polysaccharides, phyco-cyanobilins polyphenols, lectins, proteins lutein, vitamin E, B 12 and K 1 , peptides, polyunsaturated fatty acids and pigments can be highlighted. In the present review, we will discuss the biological activity of these derived compounds as antifungal/ antibacterial agents and their most promising applications. A brief outline is also given for the prospects of these isolated phytochemicals and using algae as therapeutic in the dietary form. We have also tried to answer whether alga-derived metabolites can serve as potential therapeutics for the treatment of SARS-CoV-2 like viral infections too.

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Antioxidant and Antimicrobial Activity of Algal and Cyanobacterial Extracts: An In Vitro Study

Cited by 36 publications

References 76 publications

In vitro study of biologically active properties of complexes isolated from biomass of microscopic algae

In vitro study of biologically active properties of complexes isolated from biomass of microscopic algae

Nutritional values, antioxidant, and cytotoxic activities of selected edible marine macroalgae: a comparative study

Antimicrobial therapeutics isolated from algal source: retrospect and prospect

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