Antioxidant and Antimicrobial Activities of Tunisian Azarole (<i>Crataegus Azarolus</i>L.) Leaves and Fruit Pulp/Peel Polyphenolic Extracts

Belkhir, Manel; Rebai, Olfa; Dhaouadi, Karima; Sioud, Besma; Amri, Mohamed; Fattouch, Sami

doi:10.1080/10942912.2011.586080

Cited by 18 publications

(14 citation statements)

References 36 publications

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“…Results of this study confirm that P.guagava peels possess antimicrobial activity such as peels of pomegranate and apple on both S. aureus and P. fluorescence [18,19] as well as peels of the Tunisian azarole on S. aureus and S. faecalis [20].…”

Section: Discussionsupporting

confidence: 61%

Peels of Psidium Guajava Fruit Possess Antimicrobial Properties

Abdelmalek

Mohsen

Awad

et al. 2016

int. arab. j antimicrob. agents

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Objective: Psidium guajava (guava) leaf extracts have been extensively studied for their antimicrobial effect. Yet, very few studies investigated the antimicrobial effect of the ripe guava fruit. This study aims at examining aqueous extracts of ripe Psidium guajava fruit, bulb, seeds and peels (harvested in autumn at Jordan River valley). Materials and methods:Decreasing concentrations of water extracts of three parts of the fruit were tested against Gram positive and Gram negative bacteria as well as the yeast Saccharomyces cerevesea using the agar diffusion method. Clinical isolates of methicillin resistant Staphylococcus aureus (MRSA) were also included.Results: Water extracts of Guava peels at concentrations ≥ 10% were inhibitory to coagulase positive S. aureus and MRSA strains, and at ≥1% were inhibitory to coagulase negative Staphylococci. Water extracts of peels acted synergistically with cell wall synthesis inhibitor antibiotics towards S. aureus and MRSA strains used. HPLC-MS-MS analysis through ion trap and subsequent fragmentation of the isolated ions from peels water extracts allowed the clear identification of two wellknown phenolic compounds that are known for their antimicrobial activity: Gallic acid (957.6 μg/mL) and Ferulic acid(13 μg/mL). Conclusion:The ripe fruit of Guava is a nutritionally rich fruit with an outer covering that possess antimicrobial properties.

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Section: Discussionsupporting

confidence: 61%

Peels of Psidium Guajava Fruit Possess Antimicrobial Properties

Abdelmalek

Mohsen

Awad

et al. 2016

int. arab. j antimicrob. agents

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“…73 The obtained results corroborated previous studies reporting the in vivo antioxidant and cyto-protective activities of C. azarolus water extract. 74 On the other hand, castor oil-induced acute diarrhea was accompanied by an increase of plasma inflammatory markers levels, such as C-reactive protein (CRP) and alkaline phosphatase (ALP).…”

Section: Discussionmentioning

confidence: 99%

Protective effects of Crataegus azarolus L. berries aqueous extract against castor oil–induced diarrhea, oxidative stress, and inflammation in rat

Sammari

Jedidi

Selmi

et al. 2020

Neurogastroenterology Motil

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Background: Diarrhea is a multifactorial gastrointestinal disorder responsible for about 5 million deaths annually. The chemical composition, the antioxidant activity of Crataegus azarolus berries aqueous extract (CABAE) as well as its protective effects against castor oil-induced diarrhea, oxidative stress, and inflammation in rat were studied.Methods: Sixty male rats were used and divided into six groups of ten animals in each: Control (C), castor oil (CO), CO+various doses of CABAE (100, 200, and 400 mg/kg b.w., p.o.), and CO+loperamide (LOP, 10 mg/kg b.w., p.o.).

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“…aronia (Yellow Azarole) is native to the Mediterranean countries, which have long been used in Tunisian traditional medicines to prevent cancer, diabetes, sexual weakness, and cardiovascular diseases [14]. Previous studies revealed that the leaves, flowers, and fruits of C. azarolus had various biological activities including antimicrobial, antioxidant, antihyperglycemic, and antihyperlipidemic activities [15,16]. These potential health benefits are related to their high content in many natural active compounds, such as flavonoids, minerals, sugar alcohols, carotenoids, polyphenols, amino acids, and tannins [14,17].…”

Section: Introductionmentioning

confidence: 99%

Characterization of Polysaccharides Extracted from Pulps and Seeds of Crataegus azarolus L. var. aronia: Preliminary Structure, Antioxidant, Antibacterial, α-Amylase, and Acetylcholinesterase Inhibition Properties

Rjeibi

Zaabi

Jouida

2020

Oxidative Medicine and Cellular Longevity

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Polysaccharides from the pulps (CAP) and seeds (CAS) of Crataegus azarolus L. var. aronia were extracted by hot water method. Both polysaccharides were characterized by scanning electron microscopy (SEM), Congo red test, FT-IR spectroscopy, and their antioxidant, α-amylase, antiacetylcholinesterase, and antibacterial activities were evaluated. CAP showed the highest total carbohydrate (82.35%) and uronic acid (29.39%) contents. The Congo red test revealed the lack of triple-helical conformation for both polysaccharides. The comparison of both infrared spectra indicated similar patterns with the presence of typical bands of polysaccharides. However, the microstructure of both samples indicated differences when analyzed by SEM. CAP displayed higher antioxidant, α-amylase, and acetylcholinesterase inhibitory activities. Besides, CAP showed the strongest antimicrobial effects against seven microorganisms and, notably, the Gram-positive bacteria. Overall, the results suggest that polysaccharides from C. azarolus L. var. aronia may be considered as novel sources of antioxidants and recommended as enzyme inhibitory agents in food and pharmaceutical industries.

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Antioxidant and Antimicrobial Activities of Tunisian Azarole (Crataegus AzarolusL.) Leaves and Fruit Pulp/Peel Polyphenolic Extracts

Cited by 18 publications

References 36 publications

Peels of Psidium Guajava Fruit Possess Antimicrobial Properties

Peels of Psidium Guajava Fruit Possess Antimicrobial Properties

Protective effects of Crataegus azarolus L. berries aqueous extract against castor oil–induced diarrhea, oxidative stress, and inflammation in rat

Characterization of Polysaccharides Extracted from Pulps and Seeds of Crataegus azarolus L. var. aronia: Preliminary Structure, Antioxidant, Antibacterial, α-Amylase, and Acetylcholinesterase Inhibition Properties

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