Peels of Psidium Guajava Fruit Possess Antimicrobial Properties

Abstract

Objective: Psidium guajava (guava) leaf extracts have been extensively studied for their antimicrobial effect. Yet, very few studies investigated the antimicrobial effect of the ripe guava fruit. This study aims at examining aqueous extracts of ripe Psidium guajava fruit, bulb, seeds and peels (harvested in autumn at Jordan River valley). Materials and methods:Decreasing concentrations of water extracts of three parts of the fruit were tested against Gram positive and Gram negative bacteria as well as the yeast Saccharomyces cerevesea using the agar diffusion method. Clinical isolates of methicillin resistant Staphylococcus aureus (MRSA) were also included.Results: Water extracts of Guava peels at concentrations ≥ 10% were inhibitory to coagulase positive S. aureus and MRSA strains, and at ≥1% were inhibitory to coagulase negative Staphylococci. Water extracts of peels acted synergistically with cell wall synthesis inhibitor antibiotics towards S. aureus and MRSA strains used. HPLC-MS-MS analysis through ion trap and subsequent fragmentation of the isolated ions from peels water extracts allowed the clear identification of two wellknown phenolic compounds that are known for their antimicrobial activity: Gallic acid (957.6 μg/mL) and Ferulic acid(13 μg/mL). Conclusion:The ripe fruit of Guava is a nutritionally rich fruit with an outer covering that possess antimicrobial properties.

Bacterial Communities Associated with Crude Oil Bioremediation through Composting Approaches with Indigenous Bacterial Isolate

“…Polyphenols from apple peels, for example, could inhibit the growth of a pathogenic bacterium, Listeria monocytogenes [40]. Similarly, water extracts of guava peels were also reported to inhibit the growth of Staphylococcus aureus and MRSA strains [41]. Watermelon peels have been shown to inhibit a number of microorganisms including Pseudomonas fluorescens [42].…”

Edible Medicinal Guava Fruit (Psidium guajava L.) Are a Source of Anti-Biofilm Compounds against Pseudomonas aeruginosa

“…P. guajava L. is a widely cultivated fruit plant, distributed worldwide in tropical and subtropical areas. Guava fruit is rich in vitamins A and C, iron, phosphorus, calcium, and minerals and contains various organic compounds such as (i) polyphenols with potential antimicrobial activities [ 31 ], notably the gallic and ferulic acids active against a methicillin-resistant S. aureus clinical strain [ 32 ] and (ii) sesquiterpenes with depressant activities on the central nervous system [ 33 ].…”