Antioxidant and Antibacterial Activity of Commercially Available Herbs in Korean Markets

채인경,; 김현정,; 유미희,; 김혁일,; 이인선,

doi:10.3746/jkfn.2010.39.10.1411

Cited by 18 publications

(7 citation statements)

References 9 publications

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“…Similarly, in a study by Chae et al. (2010), lemon grass extract exhibited the highest flavonoid content, moderate TPC in comparison with rosemary extract, and rather low antibacterial activity. In a study by Ouattara et al.…”

Section: Resultsmentioning

confidence: 59%

“…In turn, the results of antibacterial activities are often highly correlated with their total phenolic content-this was not confirmed in our study. Similarly, in a study byChae et al (2010), lemon grass extract exhibited the highest flavonoid content, moderate TPC in comparison with rosemary extract, and rather low antibacterial activity. In a study byOuattara et al (2011), the plant extract of Lannea velutina was the most bactericidal, whereas the Lannea acida extract exhibited the highest…”

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confidence: 79%

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Antioxidant and antibacterial properties of lemon, sweet, and cereal grasses

Sielicka-Różyńska

Gwiazdowska

2020

J. Food Process. Preserv.

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There is currently growing interest in using plants as a source of bioactive compounds that exhibit beneficial health properties. Moreover, consumers are becoming increasingly more concerned about the quality of food, thus, newly introduced products and additives should be nutritious, healthy, safe, and friendly to both the environment and animals. Much attention is currently being paid to plant-based diets that prioritize the consumption of fruits, vegetables, nuts, seeds, grains, and botanicals, and a focus on plant content reinforces observed growing interest in vegetarian and vegan products and a flexitarian lifestyle (Mintel Report, 2017). It should also be emphasized that plant extracts containing various antioxidant and antimicrobial compounds are becoming more interesting because they can be used to either prevent or retard undesirable changes, for

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Section: Resultsmentioning

confidence: 59%

mentioning

confidence: 79%

Antioxidant and antibacterial properties of lemon, sweet, and cereal grasses

Sielicka-Różyńska

Gwiazdowska

2020

J. Food Process. Preserv.

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“…DPPH was used to assess the free-radical quenching ability of newly synthesized compounds to detect their antioxidant potential according to a previously reported protocol with slight modifications. 37 The percent radical scavenging activity (%RSA) of the compounds was determined by spectrophotometric analysis at 517 nm in which a homogeneous mixture composed of a methanolic solution of DPPH (0.025 mg mL –1 ) and a 100 μM solution of the test compound was used. The following formula was used to calculate the percent free-radical scavenging activity where % FRSA is the percent free-radical scavenging activity and “Abs” is an abbreviation of “absorption”.…”

Section: Experimental Workmentioning

confidence: 99%

Development, Molecular Docking, and In Silico ADME Evaluation of Selective ALR2 Inhibitors for the Treatment of Diabetic Complications via Suppression of the Polyol Pathway

et al. 2022

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Diabetic complications are associated with overexpression of aldose reductase, an enzyme that catalyzes the first step of the polyol pathway. Osmotic stress in the hyperglycemic state is linked with the intracellular accumulation of sorbitol along with the depletion of NADPH and eventually leads to oxidative stress via formation of reactive oxygen species and advanced glycation end products (AGEs). These kinds of mechanisms cause the development of various diabetic complications including neuropathy, nephropathy, retinopathy, and atherosclerotic plaque formation. Various aldose reductase inhibitors have been developed to date for the treatment of diabetic complications, but all have failed in different stages of clinical trials due to toxicity and poor pharmacokinetic profiles. This toxicity is rooted in a nonselective inhibition of both ALR2 and ALR1, homologous enzymes involved in the metabolism of toxic aldehydes such as methylglyoxal and 3-oxyglucosazone. In the present study, we developed a series of thiosemicarbazone derivatives as selective inhibitors of ALR2 with both antioxidant and antiglycation potential. Among the synthesized compounds, 3c exhibited strong and selective inhibition of ALR2 (IC 50 1.42 μM) along with good antioxidant and antiglycative properties. The binding mode of 3c was assessed through molecular docking and cluster analysis via MD simulations, while in silico ADME evaluation studies predicted the compounds’ druglike properties. Therefore, we report 3c as a drug candidate with promising antioxidant and antiglycative properties that may be useful for the treatment of diabetic complications through selective inhibition of ALR2.

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“…Values are mean ± S.D 1. Caffeic acid was used as a standard2 Naringin was used as a standard a-e Values are significantly different as determined by Duncan's multiple test (p < 0.05)…”

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confidence: 99%

Evaluation of the EtOAc Extract of Lemongrass (Cymbopogon citratus) as a Potential Skincare Cosmetic Material for Acne Vulgaris

Kim

Park

Lee

et al. 2022

J. Microbiol. Biotechnol.

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This study evaluated the biological properties of lemongrass (Cymbopogon citratus) extracts. The EtOAc extract of lemongrass had DPPH, TEAC, and nitric oxide-scavenging activity assay results of 58.06, 44.14, and 41.08% at the concentration of 50, 10, and 50 μg/ml, respectively. The EtOAc extract had higher elastase and collagenase inhibitory activities than the 80% MeOH, n-hexane, BuOH, and water extracts and comparable whitening activity toward monophenolase or diphenolase. Also, the EtOAc fraction had higher lipase inhibitory and antimicrobial activities against Cutibacterium acnes among extracts which is known to an important contributor to the progression of inflammatory acne vulgaris, and an opportunistic pathogen present in human skin. Total phenolic and flavonoid concentrations in the EtOAc extract were 132.31 mg CAE/g extract and 104.50 mg NE/g extract, respectively. Biologically active compounds in lemongrass extracts were analyzed by LC-MS. This study confirms that lemongrass extracts have potential use as cosmetic skincare ingredients. Thus, lemongrass can be considered a promising natural source of readily available, low-cost extracts rich in antioxidant, skincare, and antimicrobial compounds that might be suitable for replacing synthetic compounds in the cosmeceutical industry.

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Antioxidant and Antibacterial Activity of Commercially Available Herbs in Korean Markets

Cited by 18 publications

References 9 publications

Antioxidant and antibacterial properties of lemon, sweet, and cereal grasses

Antioxidant and antibacterial properties of lemon, sweet, and cereal grasses

Development, Molecular Docking, and In Silico ADME Evaluation of Selective ALR2 Inhibitors for the Treatment of Diabetic Complications via Suppression of the Polyol Pathway

Evaluation of the EtOAc Extract of Lemongrass (Cymbopogon citratus) as a Potential Skincare Cosmetic Material for Acne Vulgaris

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