Antioxidant and anti-proliferative activities of different parts of Cyclamen cilicium

TURAN, Murat; Seçme, Mücahit; Mammadov, Ramazan

doi:10.25092/baunfbed.925496

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…mazziaricus taxon prepared with acetone (90.3%). Turan (2016) conducted a study to determine the antioxidant activities, phenolic substances, and flavonoids, the phenolic components with spectroscopic methods in the Cyclamen alpinum Dammann ex. Sprenger and Cyclamen parviflorum Pobed.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Effect of phosphorus fertilization on phenolic compounds and antioxidant activity in Galanthus elwesii Hook.

BATI AY,

KARA,

AÇIKGÖZ

2023

International Journal of Agriculture Environment and Food Sciences

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Snowdrop is a genus of high medicinal value with alkaloids such as galantamine, and lycorine of the Amaryllidaceae family. The present study was conducted to have an effect on the effects of phosphorus (P) treatment on antioxidant activity and phenolic compounds in Galanthus elwesii Hook. The plants were exposed to different concentrations of P ( 0, 3, 6, and 12 kg da-1). The study was carried out in the 2018-2019 growing season. G. elwesii were harvested based on different growing stages (flowering and fruit ripening). In this study, the bulb and roots of the plant were used. Total flavonoid content (TFC), total phenolic content (TPC), phenolic compounds, and antioxidant activity were determined in harvested bulb and roots. The highest TPC was detected as 358.36 mg GAE/g in the flowering period of the plant, and the lowest TPC determined as 80.13 mg GAE/g in the fruit ripening period in the treatment P 6 kg da-1. The highest TFC was detected as 108.07 mg QE/g with the flowering period of the plant, and the lowest TFC was determined as 52.33 mg QE/g in the fruit ripening period in the treatment P 6 kg da-1. The main phenolic component of G. elwesii was determined to be gallic acid (GA). In antioxidant activity, while the highest 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity (72.30%) was in the flowering period in the treatment P 6 kg da-1, the highest ferrous ions chelating activity (66.77%) was detected in the fruit ripening period in the treatment P 6 kg da-1. As a result, it was determined that TPC, TFC and DPPH activity in G. elwesii of flowering period ˃fruit ripening period.

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Section: Antioxidant Activitymentioning

confidence: 99%

Effect of phosphorus fertilization on phenolic compounds and antioxidant activity in Galanthus elwesii Hook.

BATI AY,

KARA,

AÇIKGÖZ

2023

International Journal of Agriculture Environment and Food Sciences

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Anticancer, antioxidant, and antibacterial activity of chemically fingerprinted extract from Cyclamen persicum Mill.

Al-Rimawi,

Khalid,

Salah

et al. 2024

Sci Rep

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In the last few decades, researchers have thoroughly studied the use of plants in Palestine, one of them is Cyclamen persicum Mill. (C. persicum). Cyclamen persicum has been historically cultivated since the 1700s due to its tuber. The tuber is known to stimulate the nasal receptors, thus triggering the sensory neurons. Cyclamen persicum has anti-inflammatory effects, reduces cholesterol levels, treats diabetes, and inhibits tumor growth. In this respect, in-vitro examination of antibacterial and anticancer activities and antioxidative potency of C. persicum ethanolic extract were evaluated. The antioxidative potency of the extracted plant material was determined spectrophotometrically using the DPPH free radical scavenging method and the HPLC–PDA method to evaluate its total phenolic content (TPC) and total flavonoid content (TFC). The experimental results revealed weak antibacterial activity of C. persicum extract against both gram negative (E. coli) and gram positive (Streptococcus aureus and S. aureus) bacterial strains, with the zones of inhibition found to be less than 8 mm. On the other hand, powerful activity against MCF7 breast cancer as well as HT29 colon cancer cell lines was obtained. The findings also revealed potent inhibition of free radicals and the presence of maximal levels of natural products such as phenolic compounds and flavonoids, which supportits biological activities and powerful ability to scavenge free radicals. HPLC results showed the presence of numerous flavonoid and phenolic compounds such as rutin, chlorogenic acid, kaempferol, trans-cinnamic acid, quercetin, sinapic acid, and p-coumaric acid.

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Antioxidant and anti-proliferative activities of different parts of Cyclamen cilicium

Cited by 2 publications

References 33 publications

Effect of phosphorus fertilization on phenolic compounds and antioxidant activity in Galanthus elwesii Hook.

Effect of phosphorus fertilization on phenolic compounds and antioxidant activity in Galanthus elwesii Hook.

Anticancer, antioxidant, and antibacterial activity of chemically fingerprinted extract from Cyclamen persicum Mill.

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