Antioxidant and Anti-Proliferative Activities of Oats under Different Solvent Extraction Conditions

함현미,; 우관식,; 박지영,; 이병원,; 최용환,; 이춘우,; 김욱한,; 이준수,; 이유영,

doi:10.3746/jkfn.2016.45.6.918

Cited by 5 publications

(1 citation statement)

References 25 publications

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“…It was observed that the total polyphenol content, scavenging of ABTS and DPPH radicals, and reducing power were the greatest in methanol extracts [ 118 ]. In addition, methanol extracts had the most significant inhibitory effects on the proliferation of colorectal cancer (HCT116), lung cancer (NCI-H460), and breast cancer (MCF7) cells [ 119 ]. Although there were differences in the antioxidant effects and inhibition of cancer cell proliferation of oats depending on the extraction solvent, these findings demonstrate that oats have antioxidant and anti-cancer effects [ 98 , 120 ].…”

Section: Other Bioactive Ingredients and Functionalitiesmentioning

confidence: 99%

Multiple Antioxidative and Bioactive Molecules of Oats (Avena sativa L.) in Human Health

Kim

Hwang

Yang³

et al. 2021

Antioxidants

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Oats (Avena sativa L.) are rich in protein, fiber, calcium, vitamins (B, C, E, and K), amino acids, and antioxidants (beta-carotene, polyphenols, chlorophyll, and flavonoids). β-glucan and avenanthramides improve the immune system, eliminate harmful substances from the body, reduce blood cholesterol, and help with dietary weight loss by enhancing the lipid profile and breaking down fat in the body. β-glucan regulates insulin secretion, preventing diabetes. Progladins also lower cholesterol levels, suppress the accumulation of triglycerides, reduce blood sugar levels, suppress inflammation, and improve skin health. Saponin-based avanacosidase and functional substances of flavone glycoside improve the immune function, control inflammation, and prevent infiltration in the skin. Moreover, lignin and phytoestrogen prevent hormone-related cancer and improve the quality of life of postmenopausal women. Sprouted oats are rich in saponarin in detoxifying the liver. The literatures have been reviewed and the recent concepts and prospects have been summarized with figures and tables. This review discusses recent trends in research on the functionality of oats rather than their nutritional value with individual immunity for self-medication. The oat and its acting components have been revisited for the future prospect and development of human healthy and functional sources.

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Section: Other Bioactive Ingredients and Functionalitiesmentioning

confidence: 99%

Multiple Antioxidative and Bioactive Molecules of Oats (Avena sativa L.) in Human Health

Kim

Hwang

Yang³

et al. 2021

Antioxidants

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Physicochemical properties and physiological activities of Agastache rugosa extracts

Kim¹,

Hong²

2021

Korean J. Food Preserv.

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Agastache rugosa is used as a medicinal herb and contains various polyphenol compounds. Here, we investigated the physicochemical properties; and the immunomodulatory and anti-obesity effects of Agastache rugosa extracts. Agastache rugosa was extracted with hot water (HE), 70% ethanol (EE), and 70% methanol (ME). The yield of Agastache rugosa extracts varied depending on the extraction solvents, from 6.11 to-8.86%. The total sugar content was the highest in the HE-(33.98 g/100 g). In contrast, the total polyphenol content was the highest in the ME-(10.25 g/100 g), while the total protein content was similar in all extracts. The DPPH radical scavenging activity of the ME was 61.05%, and the ABTS radical scavenging activity of the EE was 47.73% at 1,000 μg/mL. Additionally, the FRAP activity and ORAC value of the EE at 1,000 μg/mL were 1.14 μM and 121.03 μM TE/g, respectively. Importantly, all extracts decreased the production of nitric oxide in RAW 264.7 cells, and the cytokine content also decreased in a concentration-dependent manner. In addition, all extracts decreased lipid accumulation in adipocytes in vitro, compared with that in the untreated adipocytes. Therefore, Agastache rugosa extracts can potentially be used as functional materials with immunomodulatory and anti-obesity effects.

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Nutritional and Phytochemical Composition and Associated Health Benefits of Oat (Avena sativa) Grains and Oat-Based Fermented Food Products

Alemayehu

Forsido

Tola

et al. 2023

The Scientific World Journal

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Oats (Avena sativa L.) are a popular functional cereal grain due to their numerous health benefits. This review article summarized the information on the chemical composition and phytonutrients of oats grown in different countries. It also reviewed recently developed fermented oat products to highlight their potential for human health. Oats have an interesting nutritional profile that includes high-quality protein, unsaturated fats, soluble fiber, polyphenolic compounds, and micronutrients. Oat grain has a unique protein composition, with globulins serving as the primary storage protein, in contrast to other cereals, where prolamins are the main storage proteins. Oats have the highest fat content of any cereal, with low saturated fatty acids and high essential unsaturated fatty acid content, which can help reduce the risk of cardiovascular diseases. Oats are a good source of soluble dietary fiber, particularly β-glucan, which has outstanding functional properties and is extremely important in human nutrition. β-Glucan has been shown to lower blood cholesterol and glucose absorption in the intestine, thereby preventing diseases such as cardiovascular injury, dyslipidemia, hypertension, inflammatory state, and type 2 diabetes. Oats also contain high concentration of antioxidant compounds. Avenanthramides, which are unique to oats, are powerful antioxidants with high antioxidative activity in humans. Recognizing the nutritional benefits of oats, oat-based fermented food products are gaining popularity as functional foods with high probiotic potential.

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Antioxidant and Anti-Proliferative Activities of Oats under Different Solvent Extraction Conditions

Cited by 5 publications

References 25 publications

Multiple Antioxidative and Bioactive Molecules of Oats (Avena sativa L.) in Human Health

Multiple Antioxidative and Bioactive Molecules of Oats (Avena sativa L.) in Human Health

Physicochemical properties and physiological activities of Agastache rugosa extracts

Nutritional and Phytochemical Composition and Associated Health Benefits of Oat (Avena sativa) Grains and Oat-Based Fermented Food Products

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