Antioxidant and anti‐fatigue activities of egg white peptides prepared by pepsin digestion

Abstract

Among the four peptide fractions, EWPs2 possessed the strongest antioxidant activity and exhibited an anti-fatigue effect. The experimental data could clarify partially the anti-fatigue mechanisms of EWPs and provide an important basis for developing EWPs as safe and natural antioxidants and anti-fatigue agents for wide use.

Ameliorative effects of egg white hydrolysate on recognition memory impairments associated with chronic exposure to low mercury concentration

“…In addition, they have a metal chelation potential (Ding et al 2015). The presence of Tyr and Phe amino acids in the peptides is related to scavenging free radical properties (Sun et al 2014). In addition, the His residues are directly associated with metal chelating property (Gallegos-Tintore The exact mechanism by which HgCl 2 can penetrate through the BBB is unclear.…”

Egg white hydrolysate improves fatigue due to short‐term swimming load test in mice

“…These findings may explain the observed significant differences in serum creatinine kinase levels among the three groups. The antifatigue effect has also been reported for pepsin digests from EWP, and the absorption rate was considered a likely contributing factor (Sun et al., 2014). Therefore, this difference in absorption rates may be involved in the various increases in swimming time.…”

“…In a previous study, antioxidant and antifatigue effects were observed with pepsin‐degraded products of EWP at a low dose of 0.2 mg/g/day (Sun et al., 2014). As pepsin is a typical enzyme found in the stomach, it is reasonable to expect effects similar with those of the ingestion of unprocessed EWP, although it may be less effective.…”

“…First, the pepsin digest of egg white used previously was prepared by subjecting heat‐treated egg white to pepsin (Sun et al., 2014). In contrast, the EWP preparation used in the present study did not undergo any heat treatment.…”

“…Second, as opposed to the ad libitum feeding used in the present study, oral administration was used in the previous study, which likely allowed effective scheduled administration of the pepsin‐treated preparation of egg white (Sun et al., 2014). EWP do not exhibit antifatigue effects unless an appropriate dosing schedule is used.…”