Antioxidant activity of Maytenus imbricata Mart., Celastraceae

Abstract

RESUMO: "Atividade antioxidante de Maytenus imbricata Mart., Celastraceae". A atividade antioxidante, poder redutor (RP) e a atividade coletora de radicais livres (FRS) usando 2,2-difenil-1-picrilhidrazil (DPPH), e a concentração de substâncias fenólicas totais dos extratos e substâncias isoladas das folhas, caules e raízes de Maytenus imbricata Mart. (Celastraceae) foram avaliados. Alguns extratos, a mistura de compostos fenólicos e epicatequina mostraram alto poder redutor e atividade antioxidante (DPPH) em comparação com o padrão butilhidroxianisol (BHA) e ácido gálhico (GA) utilizados no ensaio. O extrato acetato de etila das folhas mosraram alto teor de substâncias fenólicas e alto poder redutor e atividade antioxidante em relação aos outros extratos. Este fato indica haver alguma relação entre a concentração de substâncias fenólicas e o poder redutor. O solvente usado no processo de extração influencia a composição química dos extratos e, consequentemente, as atividades redutoras e antioxidantes.Unitermos: Atividade antioxidante, poder redutor, Maytenus imbricata, Celastraceae. ABSTRACT:The free radical scavenging activity (FRS) using 2,2-diphenyl-1-picrylhydrazyl (DPPH), the reducer power and the total phenolic concentration of extracts and compounds isolated from leaves, branches and roots of Maytenus imbricata Mart. (Celastraceae) were evaluated. Some extracts, a mixture of phenolic compounds (MPC) and epicatechin showed higher RP and FRS (DPPH) activities in comparison with the standard butylhydroxyanisole (BHA) and galic acid (GA) used in assays. The ethyl acetate extract from leaves showed higher total phenolic content and also higher RP and FRS (DPPH) than the other extracts. These facts indicate that there are some relations between phenolic concentration in the extract and the antioxidant activity and the reducer power. The solvent used in the extraction process influences the chemical composition of the extracts and consequently its antioxidant and reducer power activities.

Antioxidant and Antiproliferative Activities of Heterofucans from the Seaweed Sargassum filipendula

“…The reducing power of the samples was quantified as described later [ 36 ]. Briefly, 4 mL of reaction mixture, containing different sample concentration in phosphate buffer (0.2 M, pH 6.6), was incubated with potassium ferricyanide (1% w/v) at 50 ºC for 20 min.…”

A Novel Approach Towards Green Synthesis of Nanodiamonds as Biocompatible Agents

“…These include free radicals, as the superoxide anion (O2) and the hydroxyl radical (-OH), and free non-radical species, as H2O2 and singlet oxygen ( 1 O2) [44]. Oxidative stress induced by oxygen radicals promotes damage to essential biomolecules such as carbohydrates, proteins, amino acids, lipids, nucleic acids among other oxidative substances [45], thus contributing to aging and installation of chronic-degeneration 03040-5 diseases, such as cancer, CVD, arthritis, gastric ulcer, among others [46,47].…”

Influence of seasonal variation on antioxidant and total phenol activity of red propolis extracts

“…These include free radicals, as the superoxide anion (O 2 -) and the hydroxyl radical (-OH), and free non-radical species, as H 2 O 2 and singlet oxygen ( 1 O 2 ) (Gülcin et al, 2005;Kumar et al, 2005;Ardestani & Yazdanparast, 2006;Borgo et al, 2010;Mosquera et al, (2009). Oxidative stress, induced by oxygen radicals promote damage to essential biomolecules such as carbohydrates, proteins, amino acids, lipids, nucleic acids among other oxidative substances (Nagai et al, 2001;Melo et al, 2006;Ardestani & Yazdanparast, 2006;Sharififar et al, 2006), thus contributing to aging and installation of chronic-degeneration diseases, such as cancer, cardiovascular diseases, arthritis, gastric ulcer, among others (Melo et al, 2006;Siddhuraju, 2007;Stratil et al, 2007;Kumaran & Karakumaran , 2007;Silva et al, 2009).…”