Antioxidant Activity of Herbal Polysaccharides and Cough Reflex

Nosálóvá, G; Jurecek, Ludovit; Hromàdková, Zdenka; Košťálová, Zuzana; Sadlonova, V.

doi:10.1007/978-94-007-6627-3_8

Cited by 8 publications

(5 citation statements)

References 20 publications

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“…In Korea and China, knotweed has been known for thousands of years as a medicinal plant [5,6]. In addition, Japanese knotweed is a plant used in phototherapy [7]. In traditional Chinese and Japanese herbal medicine, this raw material is recommended as analgesic, antipyretic, diuretic and expectorant.…”

Section: Introductionmentioning

confidence: 99%

UPLC-PDA-Q/TOF-MS identification of bioactive compounds and on-line UPLC-ABTS assay in Fallopia japonica Houtt and Fallopia sachalinensis (F.Schmidt) leaves and rhizomes grown in Poland

Lachowicz

Oszmiański

Cebulak

et al. 2018

Eur Food Res Technol

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The activity of polyphenolic compounds, triterpenoids, carotenoids, chlorophylls and antioxidants in leaves and rhizomes of Fallopia japonica Houtt and Fallopia sachalinensis (F.Schmidt) grown in Poland was investigated. Leaves and rhizomes were assessed for the presence of bioactive compounds with the ultra-performance liquid chromatography photodiode detector-quadrupole/time-of-flight mass spectrometry (UPLC-PDA-Q/TOF-MS) method, and for antioxidant activity with the on-line UPLC-ABTS screening. Forty-six polyphenolic compounds (15 phenolic acids, 12 flavones and flavonols, 11 flavan-3-ols and 8 stilbenes), were identified in Fallopia japonica and Fallopia sachalinensis. Furthermore, accurate mass measurement technique was for the first time in Fallopia japonica Houtt and Fallopia sachalinensis (F.Schmidt) in leaves and rhizomes it identified 25 new compounds belonging to carotenoids (9), chlorophylls (13) and triterpenoids (3) as well as rated the antioxidant properties of each polyphenolic compound. Major qualitative differences were found in the profiles. The leaves and rhizomes were found to be a good source not only of (average 20408.18 and 2716.42 mg/100 g dm), but also chlorophylls (average 179.97 and 43.82 mg/100 g dm), carotenoids (average 100.23 and 53.25 mg/100 g dm) and triterpenoids (average 580.87 and 434.05 mg/100 g dm). The content of bioactive compounds in Fallopia japonica Houtt was around 8.0, 4.0, 2.0 and 1.3 times higher than the content of polyphenols, chlorophylls, carotenoids and triterpenoids in Fallopia sachalinensis (F.Schmidt). The accurate identification of Fallopia bioactive compounds is an indispensable detailed knowledge of the profile and step toward better understanding of the medicinal properties of the species and also potentially more extensive use of the plant.

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Section: Introductionmentioning

confidence: 99%

UPLC-PDA-Q/TOF-MS identification of bioactive compounds and on-line UPLC-ABTS assay in Fallopia japonica Houtt and Fallopia sachalinensis (F.Schmidt) leaves and rhizomes grown in Poland

Lachowicz

Oszmiański

Cebulak

et al. 2018

Eur Food Res Technol

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“…Mucilage is a large hydrophilic polysaccharide with a highly branched structure that is able to trap water to form a gel in bronchial mucosa. The muco-adhesive properties of these polysaccharides are responsible for treating cough indirectly by the modulation of the sensitivity of cough receptors to protect them from local irritations as well as their local soothing actions and demulcent properties (Nosalova et al, 2013). Mucilage has immunomodulatory and anti-inflammatory effects (Bokov et al, 2020).…”

Section: Linseed Laooqmentioning

confidence: 99%

“…After oral administration of pectins, they can cover the mucus terminals in the epipharyngeal nerve and decrease the sensitivity of cough receptors to irritations which leads to cough suppression. Also, it is considered that these kinds of polysaccharides can increase the saliva production contributed to antitussive properties by the activation of the swallow reflex that is competing with cough reflex in the central level (Nosalova et al, 2013). Pectins have immunomodulating, antiinflammatory, and antitussive properties.…”

Section: Pumpkin Morabbamentioning

confidence: 99%

Potentials of Antitussive Traditional Persian Functional Foods for COVID-19 Therapy†

et al. 2021

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Coronavirus disease 2019 is a worldwide pandemic resulting in a severe acute respiratory syndrome. Remdesivir is the only FDA-approved drug for hospitalized patients older than age 12. It shows the necessity of finding new therapeutic strategies. Functional foods (FFs) could have co-therapeutic and protective effects against COVID-19 infection. Traditional Persian medicine (TPM), one of the safest and most popular schools of medicine for hundreds of years, has recommended potential FF candidates to manage such a global pandemic. To reveal the potential of TPM in terms of antitussive FFs, traditional Persian pharmacopoeia “Qarabadin-e-Salehi” was searched using the keywords “Soaal” and “Sorfeh.” Also, a search of MEDLINE, PubMed Central, Google Scholar, and Science Direct was performed for the relevant literature published from the inception up to March 2021. A combination of search terms including “cough, antitussive, antioxidant, anti-inflammation, antiviral, COVID-19, mucoactive, mucolytic, expectorant, and mucoregulatory” was also applied. The potential mechanism of action in SARS-CoV-2 infection was discussed. Twelve TPM FFs were found including Laooqs, Morabbas, a Saviq, a soup, and a syrup. They are combinations of two to seven ingredients. Natural compounds of mentioned formulations have the main pharmacological mechanisms including antiviral, anti-inflammatory, antioxidant, antihistamine, bronchodilator, immunomodulatory, and mucoactive effects as well as central or peripheral antitussive activities. FFs are cost-effective, easily accessible, and safe options for both treatment and prevention of COVID-19. They might have positive psychological effects along with their pharmacological effects and nutritional virtues. They could also manage persistent respiratory discomforts after recovery from COVID-19.

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“…Currently, in China it is (usually in combination with other herbs) used for treatment of inflammatory diseases (including hepatitis and suppurative dermatitis) as well as favus, jaundice, skin burns, scald, cough, amenorrhea and hyperlipidemia [12,13]. Hu Zhang contains resveratrol, polysaccharides, flavonoids, quinones and large amounts of condensed tannins [12,14]. However, tannins found in members of this genus are known to be carcinogenic [15].…”

Section: Traditional Medicinementioning

confidence: 99%

BIOLOGICALLY ACTIVE COMPOUNDS OF KNOTWEED (Reynoutria spp.)

Patočka¹,

Navrátilová²,

Ovando³

2017

Mil. Med. Sci. Lett.

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Knotweeds (Reynoutria Houtt.) are plants native to the Far East. Japanese knotweed was introduced from Japan to the unsuspecting West by the horticultural activities of Philippe von Siebold via his nursery at Leiden in the 1840s. By 1854, the plant had arrived at the Royal Botanic Gardens in Edinburgh. The plants were then sold by a large number of commercial nursery gardens around the country. Further vegetative spread followed naturally along watercourses. The knotweed is currently extremely persistant invasive plant. There is also an important source of many bioactive substances which could be used in biomedicine. The article discusses biomedically relevant constituents and its pharmacological and toxicological properties.

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Antioxidant Activity of Herbal Polysaccharides and Cough Reflex

Cited by 8 publications

References 20 publications

UPLC-PDA-Q/TOF-MS identification of bioactive compounds and on-line UPLC-ABTS assay in Fallopia japonica Houtt and Fallopia sachalinensis (F.Schmidt) leaves and rhizomes grown in Poland

UPLC-PDA-Q/TOF-MS identification of bioactive compounds and on-line UPLC-ABTS assay in Fallopia japonica Houtt and Fallopia sachalinensis (F.Schmidt) leaves and rhizomes grown in Poland

Potentials of Antitussive Traditional Persian Functional Foods for COVID-19 Therapy†

BIOLOGICALLY ACTIVE COMPOUNDS OF KNOTWEED (Reynoutria spp.)

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