UPLC-PDA-Q/TOF-MS identification of bioactive compounds and on-line UPLC-ABTS assay in Fallopia japonica Houtt and Fallopia sachalinensis (F.Schmidt) leaves and rhizomes grown in Poland

Lachowicz, Sabina; Oszmiański, Jan; Cebulak, Tomasz; Hirnle, Lidia; Siewiński, Maciej

doi:10.1007/s00217-018-3191-4

Cited by 26 publications

(81 citation statements)

References 37 publications

(54 reference statements)

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“…Literature data about proanthocyanidins identified (by using mass spectrometry) in leaves of knotweeds are rather scarce. The two available publications provide only data about monomers, monomer gallate, B-type procyanidin dimers, tetramers and dimer gallate identified in leaves of Japanese and giant knotweed [8,9]. So, this study is the first to report identification of proanthocyanidins in leaves of Bohemian knotweed.…”

Section: Hptlc-ms/ms Characterisation Of Flavan-3-ols and Proanthocyamentioning

confidence: 86%

“…Among Japanese, Bohemian and giant knotweed plant materials Japanese knotweed rhizomes were studied the most. Bioactive secondary metabolites from different groups like stilbenes [6][7][8][9], flavonoids [6][7][8][9], phenolic acids [6][7][8][9], carotenoids [9,10], chlorophylls [9] and triterpenic acids [8,9] were found in leaves of Japanese [6][7][8][9], Bohemian [10] and giant [8,9] knotweed.…”

Section: Introductionmentioning

confidence: 99%

“…Recently, we tentatively identified flavan-3-ols and B-type proanthocyanidins from monomers up to decamers (monomers-flavan-3-ols, dimers, trimers, tetramers, pentamers, hexamers, heptamers, octamers, nonamers and decamers) and some of their gallates (monomer gallates, dimer gallate, dimer digallates, trimer gallates, tetramer gallates, pentamer gallates, hexamer gallates) in Japanese knotweed rhizomes [12,13]. Other authors reported identification of monomers [8,9,[14][15][16], monomer gallates [8,14,16], dimers [8,9,15], dimer gallates [15,16] dimer digallates [15,16] trimers [15], trimer gallates [15] trimer digallates [15] tetramer [15], tetramer gallates [15], pentamers [15], heptamers [15] and octamers [15] in rhizomes of Japanese [8,9,[14][15][16], Bohemian [14,15] and giant knotweed [8,9,[14][15][16]. However, only monomers [8,9], monomer gallates [8,9], dimers [8,9], dimer gallates [8,…”

Section: Introductionmentioning

confidence: 99%

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Leaves of Invasive Plants—Japanese, Bohemian and Giant Knotweed—The Promising New Source of Flavan-3-ols and Proanthocyanidins

Bensa

Glavnik

Vovk

2020

Plants

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This is the first report on identification of all B-type proanthocyanidins from monomers to decamers (monomers—flavan-3-ols, dimers, trimers, tetramers, pentamers, hexamers, heptamers, octamers, nonamers, and decamers) and some of their gallates in leaves of Japanese knotweed (Fallopia japonica Houtt.), giant knotweed (Fallopia sachalinensis F. Schmidt) and Bohemian knotweed (Fallopia × bohemica (Chrtek & Chrtkova) J.P. Bailey). Flavan-3-ols and proanthocyanidins were investigated using high performance thin-layer chromatography (HPTLC) coupled to densitometry, image analysis, and mass spectrometry (HPTLC–MS/MS). All species contained (−)-epicatechin and procyanidin B2, while (+)-catechin was only detected in Bohemian and giant knotweed. (−)-Epicatechin gallate, procyanidin B1 and procyanidin C1 was only confirmed in giant knotweed. Leaves of all three knotweeds have the same chemical profiles of proanthocyanidins with respect to the degree of polymerization but differ with respect to gallates. Therefore, chromatographic fingerprint profiles of proanthocyanidins enabled differentiation among leaves of studied knotweeds, and between Japanese knotweed leaves and rhizomes. Leaves of all three species proved to be a rich source of proanthocyanidins (based on the total peak areas), with the highest content in giant and the lowest in Japanese knotweed. The contents of monomers in Japanese, Bohemian and giant knotweed were 0.84 kg/t of dry weight (DW), 1.39 kg/t DW, 2.36 kg/t, respectively, while the contents of dimers were 0.99 kg/t DW, 1.40 kg/t, 2.06 kg/t, respectively. Giant knotweed leaves showed the highest variety of gallates (dimer gallates, dimer digallates, trimer gallates, tetramer gallates, pentamer gallates, and hexamer gallates), while only monomer gallates and dimer gallates were confirmed in Japanese knotweed and monomer gallates, dimer gallates, and dimer digallates were detected in leaves of Bohemian knotweed. The profile of the Bohemian knotweed clearly showed the traits inherited from Japanese and giant knotweed from which it originated.

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Section: Hptlc-ms/ms Characterisation Of Flavan-3-ols and Proanthocyamentioning

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Leaves of Invasive Plants—Japanese, Bohemian and Giant Knotweed—The Promising New Source of Flavan-3-ols and Proanthocyanidins

Bensa

Glavnik

Vovk

2020

Plants

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“…stilbenes, anthraquinones, flavonols, flavonoids and flavanol gallate dimers (Kumagai et al 2005;Kawai et al 2006;Fan et al 2009). Lachowicz et al (2019) identified seventy-one potential healthpromoting compounds in leaves and rhizomes of Fallopia sachalinensis, using the ultra-performance liquid chromatography photodiode detector-quadrupole/time-of-flight mass spectrometry (UPLC-PDA-Q/TOF-MS) method. Among them, there were 15 phenolic acids, 12 flavones and flavonols, 11 flavan-3ols, 8 stilbenes, 9 carotenoids, 13 chlorophylls and 3 triterpenoids.…”

Section: Giant Knotweed (Fallopia Sachalinensis Reynoutria Sachalinementioning

confidence: 99%

Phytochemicals in bioenergy crops

2019

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The use of natural compounds derived from agricultural crops and other plants as health promoting chemicals gains tremendous growing interest in various industrial sectors as well as among people worldwide. These chemicals have been more and more employed by the food industry as food additives, functional food ingredients, nutraceuticals, by feedstuffs industry, but also by the cosmetic and pharmaceutical industries. The general idea for this interest is to use natural products as potential alternatives to synthetic chemicals. On the other hand, some plants characterized by high yield and being used as energy crops also contained significant amount of bioactive compounds. This review focuses on the wide spectrum of the phytochemicals present in available biomass plants. It is supposed that extraction of bioactive chemicals from energy crops before their energetic use may increase economical effectiveness, providing simultaneously a double benefit in the form of phytochemicals and bioenergy as value added products. This remains in line with bioeconomy, which is defined by European Commission as ''the production of renewable biological resources and the conversion of these resources and waste streams into value added products, such as food, feed, bio-based products and bioenergy''. However, the issue is still a challenging effort due to the high costs, technology readiness and regulatory hurdles.

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“…Among the 77 compounds, only 36 had previously been identified in S. officinalis L., and they all were methyl-6-O-galloyl-β-d-glucopyranoside (peak 17, 64; m/z 345), pedunculagin1 (18,23,29; m/z 785), galloyl-HHDP-glucose otherwise called corilagin isomer (25,44,55; m/z 633), di-galloyl-glucoside (37; m/z 483), methyl-4,6-digalloyl-β-d-glucopyranoside (50, 62, 71, 88; m/z 497), HHDP-galloyl-glucose (53; m/z 633), ellagic acid pentoside (60, 99; m/z 433), ellagic acid hexoside (67, 68, 102; m/z 463), di-galloyl hexoside (72, 118; m/z 483), galloyl-bis-HHDP-glucose otherwise called potentilin/casuarictin isomer (84,85,95,97,104,106; m/z 935), lambertianin C (86; m/z 1401), ellagic acid (108; m/z 300.99), trigalloyl-HHDP-glucose (92, 114; m/z 937), trigalloyl-β-D-methyl glucoside (115; m/z 649), 3,3 ,4 -O-trimethyl ellagic acid (127, 128; m/z 343), and 3,4 -O-dimethyl ellagic acid (129, 130; m/z 329) [2,3,12]. In turn, 16 compounds had earlier been detected and identified in flowers and fruits of Punica granatum but in this study were for the first time detected in the morphological parts of S. officinalis L. These compounds were referred to as: 2,3-HHDP-(α/β)-glucose (1; m/z 481), HHDP-hexoside(2,3-(S)-Hexahydroxydiphenoyl-d-glucose) (2,4; m/z 481), HHDP-hexoside(1-galloyl-2,3-hexahydroxydiphenoyl-α-glucose) (3; m/z 481), galloyl-hexoside(β-glucogallin) (5; m/z 331), galloyl-hexoside (7)(8)(9)(10)13; m/z 331), di-HHDP-glucoside (34; m/z 783), di-galloyl-HHDP-glucose (14,56,66; m/z 785), galloyl-HHDP-hexoside (77; m/z 633), and pentagalloyl-glucoside (111; m/z 939) [10,13]. Another 6 compounds belonging to the group of hydrolyzable tannins were detected during identification of Duchesnea indica and they were: di-HHDP-glucose also known as pedunculalagin isomer (15,20,24,26,27,…”

Section: Introductionmentioning

confidence: 99%

Profile and Content of Phenolic Compounds in Leaves, Flowers, Roots, and Stalks of Sanguisorba officinalis L. Determined with the LC-DAD-ESI-QTOF-MS/MS Analysis and Their In Vitro Antioxidant, Antidiabetic, Antiproliferative Potency

et al. 2020

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The aim of this study was to accurately determine the profile of polyphenols using the highly sensitive LC–DAD–ESI–QTOF–MS/MS technique and to determine in vitro antioxidant activity, the ability of inhibition of α-amylase, α-glucoamylase, and pancreatic lipase activity, and antiproliferative activity in leaves, flowers, roots, and stalks of medical plant Sanguisorba officinalis L. The results of the analysis of the morphological parts indicated the presence of 130 polyphenols, including 62 that were detected in S. officinalis L. for the first time. The prevailing group was tannins, with contents ranging from 66.4% of total polyphenols in the flowers to 43.3% in the stalks. The highest content of polyphenols was identified in the flowers and reached 14,444.97 mg/100 g d.b., while the lowest was noted in the stalks and reached 4606.33 mg/100 g d.b. In turn, the highest values of the antiradical and reducing capacities were determined in the leaves and reached 6.63 and 0.30 mmol TE/g d.b, respectively. In turn, a high ability to inhibit activities of α-amylase and α-glucoamylase was noted in the flowers, while a high ability to inhibit the activity of pancreatic lipase was demonstrated in the leaves of S. officinalis L. In addition, the leaves and the flowers showed the most effective antiproliferative properties in pancreatic ductal adenocarcinoma, colorectal adenocarcinoma, bladder cancer, and T-cell leukemia cells, whereas the weakest activity was noted in the stalks. Thus, the best dietetic material to be used when composing functional foods were the leaves and the flowers of S. officinalis L., while the roots and the stalks were equally valuable plant materials.

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UPLC-PDA-Q/TOF-MS identification of bioactive compounds and on-line UPLC-ABTS assay in Fallopia japonica Houtt and Fallopia sachalinensis (F.Schmidt) leaves and rhizomes grown in Poland

Cited by 26 publications

References 37 publications

Leaves of Invasive Plants—Japanese, Bohemian and Giant Knotweed—The Promising New Source of Flavan-3-ols and Proanthocyanidins

Leaves of Invasive Plants—Japanese, Bohemian and Giant Knotweed—The Promising New Source of Flavan-3-ols and Proanthocyanidins

Phytochemicals in bioenergy crops

Profile and Content of Phenolic Compounds in Leaves, Flowers, Roots, and Stalks of Sanguisorba officinalis L. Determined with the LC-DAD-ESI-QTOF-MS/MS Analysis and Their In Vitro Antioxidant, Antidiabetic, Antiproliferative Potency

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