2008
DOI: 10.1016/j.bpc.2008.07.001
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Antioxidant activity of conjugated linoleic acid isomers, linoleic acid and its methyl ester determined by photoemission and DPPH techniques

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Cited by 78 publications
(55 citation statements)
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“…The same researchers have suggested that the high scavenging activity of CLAs against DPPH• free radicals may contribute to their biological activity. This observation is in agreement with findings by Fagali & Catalá (2008), who also demonstrated the ability of isomers of CLAs to reduce free radicals using a photoemission test (lipid peroxidation of PUFAs was induced by tert-butyl hydroperoxide (TBH) and the reduction in chemiluminescence, brought about by adding isomers of CLAs, was monitored) and a spectrophotometric assay (the decrease in absorbance of a solution containing the DPPH• radical through the addition of the isomers of CLAs was monitored).…”
Section: Introductionsupporting
confidence: 78%
“…The same researchers have suggested that the high scavenging activity of CLAs against DPPH• free radicals may contribute to their biological activity. This observation is in agreement with findings by Fagali & Catalá (2008), who also demonstrated the ability of isomers of CLAs to reduce free radicals using a photoemission test (lipid peroxidation of PUFAs was induced by tert-butyl hydroperoxide (TBH) and the reduction in chemiluminescence, brought about by adding isomers of CLAs, was monitored) and a spectrophotometric assay (the decrease in absorbance of a solution containing the DPPH• radical through the addition of the isomers of CLAs was monitored).…”
Section: Introductionsupporting
confidence: 78%
“…Some authors showed that linoleic acid, conjugated linoleic acid, and linoleic methyl ester have antioxidative activity and proposed this as a possible explanation for anticarcinogenic and antiatherogenic effects. Nevertheless, additional studies are necessary to show their free radical-scavenging activity in different radical systems and under physiological conditions, and to determine whether there is any link between their radical-scavenging properties and their biological effects (Fagali & Catalá, 2008).…”
Section: Compoundmentioning
confidence: 99%
“…The contradictory conclusions due to the presence of both trans configuration and conjugated double bond which may lead to stability and initiation of lipid autoxidation which can serve as pro-oxidant (Santos-Zago et al, 2008). The possible way of explaining CLA antioxidant activity is based on the anticarcinogenic and antiatherogenic effect by suppressing their free radical (Fagali and Catala, 2008) ) also confirms that different CLA isomers either individual such as t10, c12-CLA or mix can increase higher muscle antioxidant enzyme (CAT and GSH-Px) production which accompanied by an enhancement in H 2 O 2 . It can also maintain redox balance during aging process (Rahman et al, 2009).…”
Section: Cla Role On Antioxidant Activitymentioning
confidence: 66%