Antioxidant activity of benzoxazolinonic and benzothiazolinonic derivatives in the LDL oxidation model

Antioxidant properties and inhibitory effects of Satureja khozestanica essential oil on LDL oxidation induced–CuSO4 in vitro

“…There is experimental evidence indicating that different antioxidant compounds given at high pharmacological doses are effective in decreasing both atherogenesis and LDL oxidation in animals. In humans, supplementation with antioxidants combined at physiological doses is not effective in decreasing atherogenesis [5] . Researchers are recently interested in investigation and research into extraction of natural antioxidants from medical herbs to replace synthetic antioxidants.…”

Antioxydant activity of β-carboline derivatives in the LDL oxidation model

“…Hence, free radical scavengers are expected to be promising drugs for treatment of these diseases by scavenging free radicals and therefore removing oxidative stress. In a previous paper we discussed about the relationship between melatonin derivatives and atherosclerosis [36]. The biological properties look important in term of prevention of cardiovascular diseases but the capacity of molecules to inhibit atherogenic lipoprotein oxidation in vitro offers no prediction of their capacity to inhibit in vivo atherosclerosis development.…”

“…In particular, compound GWC22 has been shown to display better antioxidant properties than melatonin towards peroxyl-induced peroxidation of a linoleate model system [34,35]. Compound GWC22, used as reference, allowed to described a series of benzazolone derivatives with antioxidant activity [36].…”

Analytical and Preparative Chiral Separation of β-Carboline Derivatives, LDL Oxidation Inhibitors, Using HPLC and CE Methodologies: Determination of Enantiomeric Purity

“…These antioxidant b-carboline derivatives are of a growing interest since they still were the object of two recent articles published in 2009 [9] and in 2011 [10].…”