Antioxidant Activity of Apis Mellifera sp. Propolis Extract from Java (Indonesia)

Wiwekowati,; Astawa, Putu; Jawi, I Made; Sabir, Ardo

doi:10.21744/irjeis.v3i5.530

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…The EC50 of the polyphenol extract 3.17 g/l is higher than the EC50 of the aqueous and methanolic extracts which have 9.11 and 4.20 g/l. The result obtained may show that polyphenols are responsible for the antioxidant activity of Calendula officinalis (Shahidi & Zhong, 2015;Wiwekowati et al, 2017;Yadnya et al, 2016). The highest antioxidant activity correlated with polyphenol content was obtained for extracts prepared with methanole.…”

Section: Free Radical (Dpph) Scavenging Activity Of Alcaloides Extrac...mentioning

confidence: 83%

Phytochemical study of two plants: Calendula officinalis and Berberis vulgaris and evaluation of their antioxidant activities with DPPH test

Gougue,

Boutaiba

2024

ijhs

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Plants have been the basis of traditional medicine throughout the world and continue to provide new remedies for humanity, so a great effort has been made to use available experimental techniques to identify natural antioxidants from plants. Several authors have examined the beneficial uses of these plant species. In order to contribute to the valorization of the Algerian flora, we are interested in this study by phytochemical study of two plants of Calendula officinalis and Berberis vulgaris which are much used in the traditional medicine at the region of Djelfa and evaluate their antioxidant activity with the DPPH test. The qualitative phytochemical examination of Berberis vulgaris root showed the presence of alkaloids, tannins, sterols, triterpenes and reducing compounds in large quantities, and it also revealed lower amounts of coumarins, terpenoids, saponins and mucilage. Phytochemical studies of the dried petals of calendula officinalis revealed the presence of tannins, alkaloids, Sterols and Triterpenes, and saponosides. The tests for flavonoids and coumarins were negative on our extract. The antioxidant activity of Berberis vulgaris root was measured by the DPPH free radical scavenging technique.

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Section: Free Radical (Dpph) Scavenging Activity Of Alcaloides Extrac...mentioning

confidence: 83%

Phytochemical study of two plants: Calendula officinalis and Berberis vulgaris and evaluation of their antioxidant activities with DPPH test

Gougue,

Boutaiba

2024

ijhs

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“…In the work of Souza et al [72], A. mellifera extracts, obtained by hydrodistillation, exhibited high antioxidant activity evaluated by free radical DPPH sequestration and β-carotene/linoleic acid methods. The authors linked these results to the presence of the following compounds: prenylated benzophenones, epinemorosone, xanthochymol, gambogenone, and aristophenone A. Wiwekowati et al [73] also attributed the high antioxidant potential of A. mellifera to the structure of its flavonoids and phenolic acids, which was evaluated by inhibition of free radical DPPH.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Volatile Compounds, Chemical Composition and Biological Activities of Apis mellifera Bee Propolis

Cruz¹,

Silva²,

Costa³

et al. 2020

Essential Oils - Bioactive Compounds, New Perspectives and Applications

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Propolis is a wax-like resin collected by bees from tree shoots and/or other botanical sources that is used as glue to seal cracks or open spaces in the hive. Its color varies from green to brown and reddish, depending on its botanical origin. Among the substances that can be found in propolis, low molecular weight compounds, such as monoterpenes and sesquiterpenes are the most common. Several biological activities are attributed to these classes of substances, such as antifungal, antibacterial, and others. The objective of this work was to evaluate the chemical composition of volatile compounds present in propolis samples and to analyze their correlation with biological activities.

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Indonesian Propolis Reduces Malondialdehyde Level and Increase Osteoblast Cell Number in Wistar Rats with Orthodontic Tooth Movement

Wiwekowati¹,

Maâ€TMruf²,

Walianto³

et al. 2020

Open Access Maced J Med Sci

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AIM: The aim of this study was to determine the antioxidant activity of Indonesian propolis gel 5% in Wistar rats alveolar bone, toward malondialdehyde serum levels and osteoblast cells number caused by orthodontic tooth movement (OTM). METHODS: This was an experimental study using the post-test only group design. The samples were 28 male Wistar rats, divided into four groups: G1 (control group) – group without OTM and without propolis, G2 – group without OTM and with propolis, G3 – group with OTM and without propolis, and G4 – group with OTM and with propolis. Propolis available in the form of 5% gel and 30 gf helical spring force of OTM applied. Spring was applied in rat maxilla incisors. OTM treatment was given 17 days, and on day 18, blood samples were taken for the measurement of malondialdehyde levels, then tested using the ELISA test. Variable of osteoblast was calculated histologically using hematoxylin-eosin staining. The data of malondialdehyde level and the osteoblast number obtained were tested using one-way ANOVA. RESULTS: The result indicated that osteoblast number was higher with propolis application compared to those without propolis in the control group and orthodontic tooth treatment group (G2>G1, 23.97 ± 2.95 vs. 18.63 ± 3.04 and G4>G3, 34.17 ± 5.57 vs. 28.26 ± 2.62) with significant difference (p < 0.05). Propolis application also reduces malondialdehyde serum level when compared to both groups without propolis (control and OTM group) (G2<G1, 1.02 ± 0.18 nmol/ml vs. 1.55 ± 0.24 nmol/ml and G4<G3 1.29 ± 0.22 nmol/ml vs. 1.83 ± 0.21 nmol/ml) and significantly different (p < 0.05). OTM increased the malondialdehyde level compared to the control group, with a significant difference (p < 0.05). CONCLUSION: Propolis gel 5% application can reduce malondialdehyde serum level and could increase the number of osteoblast.

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Antioxidant Activity of Apis Mellifera sp. Propolis Extract from Java (Indonesia)

Cited by 3 publications

References 6 publications

Phytochemical study of two plants: Calendula officinalis and Berberis vulgaris and evaluation of their antioxidant activities with DPPH test

Phytochemical study of two plants: Calendula officinalis and Berberis vulgaris and evaluation of their antioxidant activities with DPPH test

Volatile Compounds, Chemical Composition and Biological Activities of Apis mellifera Bee Propolis

Indonesian Propolis Reduces Malondialdehyde Level and Increase Osteoblast Cell Number in Wistar Rats with Orthodontic Tooth Movement

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