Antioxidant Activity of Antiviral Proteins from Celosia cristata

Gholizadeh, Ashraf; Kumar, Manoj; Balasubrahmanyam, A.; Sharma, Sushil; Narwal, Sneh; Lodha, M. L.; Kapoor, H. C.

doi:10.1007/bf03263184

Cited by 36 publications

(15 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Purified SOD was also reported to have RIP activity [65] and the tobacco protein had a sequence similar to that of SOD, thus leading to the hypothesis that the two proteins had dual enzymatic activity. An antioxidant activity of RIPs from Celosia cristata has also been reported [66].…”

Section: Enzymatic Activitymentioning

confidence: 94%

Ribosome-inactivating proteins: progress and problems

Stirpe

Battelli

2006

Cell. Mol. Life Sci.

318

225

View full text Add to dashboard Cite

Ribosome-inactivating proteins (RIPs), mostly from plants, are enzymes which depurinate rRNA, thus inhibiting protein synthesis. They also depurinate other polynucleotide substrates. The biological activity of RIPs is not completely clarified, and sometimes independent of the inhibition of protein synthesis. There are differences in the cytotoxicity of RIPs and, consequently, in their toxicity to animals. Some RIPs are potent toxins, the best known being ricin, a potential biological weapon. New toxins have recently been identified. RIPs cause apoptotic and necrotic lesions, and induce production of cytokines causing inflammation. RIPs are potentially useful in agriculture and medicine because (i) they have antiviral activity and (ii) they are used for the preparation of conjugates with antibodies ('immunotoxins') or other carriers, rendering them specifically toxic to the cell target of the carrier, which may be helpful in therapy. The distribution, mechanism of action and role in nature of RIPs are not completely understood, and we can expect several future developments in their practical application.

show abstract

Section: Enzymatic Activitymentioning

confidence: 94%

Ribosome-inactivating proteins: progress and problems

Stirpe

Battelli

2006

Cell. Mol. Life Sci.

318

225

View full text Add to dashboard Cite

show abstract

“…Systemic acquired resistance (SAR) can be applied as an alternative to the traditional methods of plant protection. In many of recent approaches involving viral components, the induced resistance is very specific to a particular strain or group of viruses (Gholizadeh et al, 2004). Biological and chemical means are used to systematically induce the resistance in many plant species (Ryals, Uknes, & Ward, 1994;Spletzer & Enyedi, 1999).…”

mentioning

confidence: 99%

Essential Oils and Latices as Novel Antiviral Agent Against Potato Leaf Roll Virus and Analysis of Their Phytochemical Constituents Responsible for Antiviral Activity

Iftikhar¹,

Shahid²,

Javed³

et al. 2013

JAS

View full text Add to dashboard Cite

The present work was aimed to limit the practice of using pesticides in the managing program of the potato leaf roll disease on potato plants as the misuse of some pesticides had caused severe problems. The study was focused to find compounds nontoxic and safe for the biome. The antiviral activity of essential oils and latices tapped from different plants was investigated against potato leaf roll virus (PLRV). Essential oils from Eucalyptus citriodora leaves, Clove buds, and Fennel seeds were extracted. Latex of Aloe vera, Calotropis procera and Ficus elastic were collected. Essential oil and latex spray solutions were prepared at 5 and 10% concentration. All the sprayings were done at 7 days interval. Inhibition of viral replication was monitored by amplification of PLRV capsid protein gene and mRNA expression using RT-PCR technique. Results depicted inhibitory potential of all the tested essential oils and latices against PLRV infestation and also the effect was found concentration dependent. Our data showed that Aloe vera latex and clove essential oil caused maximum inhibition viral mRNA at 10% concentration. Qualitatively analyzed Tannin, Phlobactanins, Saponin, Flavonoids, Sterols and Terpens from essential oils and latices gave positive results in most of the oils and lesser content in plant latices. In the GC-MS analysis, high contents of some bioactive phytochemical compounds identified were Eugenol in Clove buds, Eucalyptol, D-Limonene and L-Limonene both in Eucalyptus leaves and Fennel seed oils and Fenchone in Fennel seeds. As this research work illustrates, there is innumerable potential of plants essential oils/latex waiting to be evaluated and exploited against genetically and functionally diverse plant viruses.

show abstract

“…Effects of different stresses on PAL activity has been previously reported (Dixon and Paiva, 1995;Ritter and Schulz, 2004;Gholizadeh et al, 2004). …”

Section: Discussionmentioning

confidence: 99%

Activation of phenylalanine ammonia lyase as a key component of the antioxidative system of salt-challenged maize leaves

Gholizadeh

Kohnehrouz

2010

Braz. J. Plant Physiol.

Self Cite

View full text Add to dashboard Cite

Differential antioxidative activities were assessed in the leaves of two maize inbreds (A-180 and A-619) under salt stress and the subsequent recovery period. Total antioxidation test revealed that in both inbreds, this ability was sharply increased during stress period, but was slowly reverted back to the normal level during recovery. The enzymatic antioxidative analysis showed differential patterns in the activities of catalase, peroxidase and polyphenol oxidase in both maize inbreeds. Comparative analysis of the activity of phenylalanine ammonia lyase (PAL), a key enzyme at the gateway of propanoid biosynthetic pathway, suggested that propanoid compounds might be antioxidants of pivotal importance to the salt-challenged maize antioxidation system. As for drought-stressed plants, a PAL-dependent antioxidative strategy is proposed as a promising target for maize salt resistance engineering.

show abstract

Antioxidant Activity of Antiviral Proteins from Celosia cristata

Cited by 36 publications

References 25 publications

Ribosome-inactivating proteins: progress and problems

Ribosome-inactivating proteins: progress and problems

Essential Oils and Latices as Novel Antiviral Agent Against Potato Leaf Roll Virus and Analysis of Their Phytochemical Constituents Responsible for Antiviral Activity

Activation of phenylalanine ammonia lyase as a key component of the antioxidative system of salt-challenged maize leaves

Contact Info

Product

Resources

About