Antiobesity Effect of the Cucubita moschata Duch Extracts in 3T3-L1 Adipocyets

Do, Gun-Pyo; Lee, Hye-Jin; Do, Jeong-Ryong; Kim, Hyun-Ku

doi:10.11002/kjfp.2012.19.1.138

Cited by 12 publications

(2 citation statements)

References 18 publications

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“…국내에서 재배되는 호박은 동양계(Cucurbita moschata P.), 페포계(Cucurbita pepo L.) 및 서양계(Cucurbita maxima D.)로 구분되고 (Cho, 2002), 주로 재배되고 있 는 호박은 동양종 호박에 속한다. 동양계 호박은 청과와 숙과가 모두 식용으로 소비되고 우리나라에서 오래전부 터 재배되어 왔다 (Do et al, 2012). 이 계통의 호박은 저온에 약하고 고온다습한 지대에서 생육이 왕성하며 병 해충에 강한 특성을 가지고 있다 (NIHHS, 2013).…”

Section: 서 론unclassified

Seedling Quality, and Early Growth and Fruit Productivity after Transplanting of Squash as Affected by Plug Cell Size and Seedling Raising Period

Kim

Park²,

Jeong³

2019

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This research was conducted to figure out the optimal size of the plug cell and seedling raising period in 'Nongwoo' and 'Nonghyeop' cultivars. In the first experiment on effect of plug cell size on growth of squash, seedlings were transplanted into hydroponic cultivation beds at different growing stages: Those in 32-cell trays with 3-4 true leaves at 25 days after sowing, those in 50-cell trays with 2 true leaves at 15 days after sowing, those in 105-cell trays just before a true leaf development, and those in 162-cell trays with only cotyledons at 8 days after sowing. In the second experiment on effect of seedling raising period on growth of squash, it was conducted to have different sowing dates. But the same transplanting date, based on the results of Experiment 1, and compared the differences in growth and fruit productivity as affected by plug cell size in the same way with experiment 1 including the cultivars and environmental conditions. After setting the transplanting date in advance, the number of days for sowing were calculated back for each treatment. In the first experiment, plant height was the greatest in 105-cell trays followed by 162, 50 and 32-cell trays in both cultivars. The best fruit quality was found in different treatments depending on the cultivars, although it was the lowest in 32-cell trays in both cultivars. The fruit quality was not significantly different among those from cell sizes. Therefore, when raising seedlings in 105-cell trays, the period of raising seedlings can be shortened as compared with the conventional 32-cell trays, and this change could reduce the workforce required for growing and transplanting seedlings. In the second experiment, after transplanting, shoot height and leaf width in the first measurement in both cultivars were greater in the 32-cell treatment. However, the last measurement after four weeks showed no significant difference in plant height, but significantly greatest leaf width in the smallest cell treatment, even as compared with that in 32-cell treatment. In case of 'Nongwoo', length and weight of the first harvested fruit showed the highest values in the treatment of 105-cell trays. In case of 'Nonghyeop' the 162-cell treatment along with the 105-cell treatment showed greatest length and weight of the first fruits. From these results, zucchini plug seedlings can be raised in plug trays with reduced cell sizes than the conventional 32-cell trays with improved fruit productivity.

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Section: 서 론unclassified

Seedling Quality, and Early Growth and Fruit Productivity after Transplanting of Squash as Affected by Plug Cell Size and Seedling Raising Period

Kim

Park²,

Jeong³

2019

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“…추출물은 in vitro실험에서 항산화 및 항암효과가 보고되었 고(4), 호박의 과육부위의 탄수화물로는 포도당, 과당, 설탕 등이 주를 이루며, 세린과 아스파르트산 등의 아미노산 함 량이 높아 위장이 약한 사람이나 회복기의 환자, 부종의 완화 (5). 늙은 호박 추출물의 지방세포에 대한 항비만 효과 등이 보고되고 있다 (6). 또한, 염증억제 효능을 보인 소재로 서 출산 후 산후 조리나 미용의 목적으로 호박은 많이 섭취 되어 왔다 (7).…”

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Inflammation inhibitory effect of water extract from pumpkin’s tendril

Jeong¹,

Choi²,

Lee³

et al. 2017

Korean Journal of Food Preservation

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Pumpkin has long been used as traditional health materials in oriental medicine, pharmacy, medicine, and food industries in many countries. In this study, the water extract and two active components from tendril of young C. moschata Duch. were investigated on inflammation inhibitory activity. The water extract of young C. moschata Duch. showed high cell viability over 95% and it decreased the production of interlukin 6 (IL-6) and tumor necrosis factor (TNF-α) in the capacity of mouse bone marrow-derived macrophages (BMDM) upon lipopolysaccharide (LPS) stimulation. Also, isolated fraction (B4) suppressed the secretion of IL-6 and TNF-α. Among the domestically cultivated pumpkins, B4 fraction contained in the tendril part of them and it comprised of the order of tendril from Cucurbita pepo var. cylindrica, old of C. moschata Duch., and young of C. moschata Duch. These results suggest that water extracts of C. moschata Duch. and purified active compound, rutin, show anti-inflammation activity by suppression of the secretion of IL-6 and TNF-α. It can be applicable as pharmaceutical materials.Key words：Cucurbita moschata Duch., tendril, inflammation inhibitory effect, interleukin 6, tumor necrosis factor α 서 론 1)

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Antioxidant Effect of Hot water and Ethanol extracts from Cheonnyuncho (Opuntia humifusa) on Reactive Oxygen Species (ROS) Production in 3T3-L1 Adipocytes

Yoon¹,

Lee²,

Kim³

et al. 2012

Korean Journal of Food Preservation

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Recently, NADPH oxidase 4 (NOX4)-mediated generation of intracellular reactive oxygen species (ROS) was proposed to accelerate adipogenesis of 3T3-L1 cell. We have previously shown that Cheonnyuncho (Opuntia humifusa) extract significantly inhibited adipocyte differentiation via downregulation of PPARγ (peroxisome proliferator-activated receptor gamma) gene expression. In this study, we focused on the molecular mechanism(s) of NOX4, G6PDH (glucose-6-phosphate dehydrogenase) and antioxidant enzymes in anti-oxidative activities of 3T3-L1 adipocytes. Our results indicate that Cheonnyuncho extracts markedly inhibits ROS production during adipogenesis in 3T3-L1 cells. Cheonnyuncho extracts suppressed the mRNA expression of the pro-oxidant enzyme such as NOX4 and the NADPH-producing G6PDH enzyme. In addition, treatment with Cheonnyuncho extract was found to upregulate mRNA levels of antioxidant enzymes such as Mn-SOD (manganese-superoxide dismutase), Cu/Zn-SOD (copper/zinc-SOD), glutathione peroxidase (GPx), glutathion reductase (GR), and catalase, all of which are important for endogenous antioxidant responses. These data suggest that Cheonnyuncho extract may be effective in preventing the rise of oxidative stress during adipocyte differentiation through mechanism(s) that involves direct down regulation of NOX4 and G6PDH gene expression or via upregulation of endogenous antioxidant responses.

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Antiobesity Effect of the Cucubita moschata Duch Extracts in 3T3-L1 Adipocyets

Cited by 12 publications

References 18 publications

Seedling Quality, and Early Growth and Fruit Productivity after Transplanting of Squash as Affected by Plug Cell Size and Seedling Raising Period

Seedling Quality, and Early Growth and Fruit Productivity after Transplanting of Squash as Affected by Plug Cell Size and Seedling Raising Period

Inflammation inhibitory effect of water extract from pumpkin’s tendril

Antioxidant Effect of Hot water and Ethanol extracts from Cheonnyuncho (Opuntia humifusa) on Reactive Oxygen Species (ROS) Production in 3T3-L1 Adipocytes

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