Antinociceptive effect of Phlomis olivieri Benth., Phlomis anisodonta Boiss. and Phlomis persica Boiss. total extracts

Sarkhail, Parisa

doi:10.1016/s1043-6618(03)00151-8

Cited by 40 publications

(19 citation statements)

References 21 publications

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“…Sarkhail et al (2003) confirmed the analgesic properties of three Phlomis species and proved their pain reliving activity.…”

Section: Antinociceptive Activity (In Vivo)supporting

confidence: 57%

“…Total extract of Phlomis olivieri and Phlomis anisodonta at a dose of 150 mg kg −1 and Phlomis persica at a dose of 100 mg kg −1 reduce significantly the number of acetic acid-induced writhes in mice, revealing antinociceptive properties comparable to indomethacin (Sarkhail et al, 2003). Mohajer et al (2005) reported analgesic properties of Phlomis lanceolata total extract and four fractions (diethyl ether, ethyl acetate, n-butanol and water extracts).…”

Section: Antinociceptive Activity (In Vivo)mentioning

confidence: 99%

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Phytochemistry and biological activities of Phlomis species

Amor

Boubaker

Sgaier

et al. 2009

Journal of Ethnopharmacology

144

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“…Sarkhail et al (2003) confirmed the analgesic properties of three Phlomis species and proved their pain reliving activity.…”

Section: Antinociceptive Activity (In Vivo)supporting

confidence: 57%

Section: Antinociceptive Activity (In Vivo)mentioning

confidence: 99%

Phytochemistry and biological activities of Phlomis species

Amor

Boubaker

Sgaier

et al. 2009

Journal of Ethnopharmacology

144

View full text Add to dashboard Cite

“…The antidynous activity of CSPG was evaluated by the writhing test as described by other studies (Sarkhail et al, 2003). Doses of 12.6, 25.2 and 50.4 g/kg of the CSPG which were i.g.…”

Section: Effect Of Cspg On Acetic Acid-induced Painmentioning

confidence: 99%

The pharmacological activities of Compound Salvia Plebeia Granules on treating urinary tract infection

Miao-miao¹,

Fang²,

Hu³

et al. 2010

Journal of Ethnopharmacology

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“…[11] Various activities such as antinociceptive,[1213] antigenotoxic and antioxidant,[14] antiulcerogenic, anticancer, anti-inflammatory and antiallergic activities have been reported for some Phlomis species. [11] This genus is rich in terpenoids, iridoids, flavonoids and other phenolic compounds that contribute potential biological effects like antioxidant activities to many of them.…”

Section: Introductionmentioning

confidence: 99%

Effect of Phlomis persica on glucose levels and hepatic enzymatic antioxidants in streptozotocin-induced diabetic rats

et al. 2010

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Methanol extract of the aerial parts of Phlomis persica Boiss. (Lamiaceae) (PPE) was studied to evaluate the effects of antidiabetic potential, by measuring fasting blood glucose, insulin, total antioxidant power (TAP), using ferric reducing antioxidant power (FRAP), lipid peroxidation (using thiobarbituric acid reactive substances, TBARS), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) on streptozotocin-induced diabetes in rats. Male Wistar rats were randomly divided into five groups of six animals each. Oral administration of PPE at doses of 100 and 200 mg/kg once a day for 10 days resulted in a significant reduction in fasting blood glucose and an increase in serum insulin levels, in comparison with diabetic control group. It also prevented diabetes-induced loss in body weight. Hepatic TAP increased and TBARS decreased following PPE treatments. The extract at 100 and 200 mg/kg increased the activity of hepatic SOD, CAT, and GPx in diabetic rats. It is concluded that PPE has antidiabetic potential that is comparable with glibenclamide. In conclusion, the results of the present study show positive effects of P. persica on experimental diabetes and thus the antidiabetic effect of PPE is related to its potential to inhibit hepatocellular oxidative stress.

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Antinociceptive effect of Phlomis olivieri Benth., Phlomis anisodonta Boiss. and Phlomis persica Boiss. total extracts

Cited by 40 publications

References 21 publications

Phytochemistry and biological activities of Phlomis species

Phytochemistry and biological activities of Phlomis species

The pharmacological activities of Compound Salvia Plebeia Granules on treating urinary tract infection

Effect of Phlomis persica on glucose levels and hepatic enzymatic antioxidants in streptozotocin-induced diabetic rats

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