Antineoplastic effects of butanolic residue of Pfaffia paniculata

Klebsiella pneumoniae Planktonic and Biofilm Reduction by Different Plant Extracts: In Vitro Study

“…The results obtained with P. paniculata are difficult to discuss, since the articles in the literature address only their anticancer and antitumor [27, 28], anti-inflammatory [29], and cell activity modulator [30] effects, among others. However, until the present moment, there is no research with this extract regarding its antimicrobial potential, which makes our study of great importance, while opening new perspectives for studies with promising results.…”

Inhibition of ascitic ehrlich tumor cell growth by intraperitoneal injection of Pfaffia paniculata (Brazilian ginseng) butanolic residue

“…Results also whowed that the same dose of BR did not induce toxicity in mice. Oral treatment with BR of P. paniculata caused an increase in lifespan of Ehrlich ascitis tumor bearing mice (Matsuzaki et al, 2006). Reduction of the ascitic fluid volume was also observed.…”

“…Previous studies have shown that the Brazilian ginseng, P. paniculata, presents both antineoplastic (Matsuzaki et al 2003, Matsuzaki et al, 2006, Carneiro et al, 2007, Nagamine et al, 2008 and cancer chemopreventive properties (Silva et al, 2005). The whole powdered root presented antineoplastic effects against Ehrlich ascites tumor (Matsuzaki et al 2003), and chemopreventive activity in a mouse hepatocarcinogenesis model (Silva et al, 2005).…”

“…The methanolic extract of P.paniculata decreased the angiogenesis in the mouse cornea model (Carneiro et al, 2007), indicating a possible antiproliferative effect. The oral administration of the butanolic residue presented inhibitory effects on Ehrlich tumor bearing mice, increasing the survival time (Matsuzaki et al, 2006) and also antineoplastic effects on mammary tumor cells MCF7 (Nagamine et al, 2008). These results led to investigate the role of the butanolic extract when administered topically in ascitis bearing mice.…”

Effects of a Brazilian herbal compound as a cosmetic eyecare for periorbital hyperchromia (“dark circles”)

“…36,37 These biological effects are attributed to pfaffic acid and the saponins Pfaffosides, which have been shown to be the most bioactive secondary metabolites of P. paniculata. [37][38][39][40] Another ingredient of PPLAC is the Brazilian plant Ptychopetalum olacoides B. (Olacaceae) known as ''Marapuama,'' that is also traditionally used as an adaptogenic.…”