Antimutagenic Effect of Medicinal Plants<i>Achillea millefolium</i>and<i>Bauhinia forficata In Vivo</i>

Düsman, Elisângela; Almeida, Igor Vivian de; Coelho, Ana Carolina; Balbi, Thiago José; Tonin, Lilian Tatiani Düsman; Vicentini, Verônica Elisa Pimenta

doi:10.1155/2013/893050

Cited by 22 publications

(23 citation statements)

References 36 publications

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“…Nowadays, common yarrow is used in healing ointments applied to wounds [7] and in modern medicine for reducing ulcer size [8]. It also has antitumor [9], antioxidant [10], antimicrobial [3], antifungal [11], anti-mutagenic [12], liver protective [13], muscle relaxant [14], gastric anti-secretory and gastroprotective activities [15].…”

Section: Introductionmentioning

confidence: 99%

Yield and chemical composition of essential oil of Achillea millefolium L. as affected by harvest time

Aziz¹,

Badawy

Zheljazkov

et al. 2018

Egypt. J. Chem.

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A chillea millefolium is an important medicinal and aromatic plant and is grown commercially for production of essential oil in many countries including Egypt. The plant extract and essential oil possess antioxidant, antimicrobial, antispasmodic and antitumor properties. We hypothesized that the essential oil content and composition may be influenced by harvest time and environmental conditions. Thus, flowering heads yield and the essential oil content and quantitative composition were investigated during different harvest times in the Experimental Station of National Research Centre at Nubaria, Beheira Governorate, West of Nile Delta, Egypt under drip irrigation. Flowering heads yield and essential oil composition varied according to harvest time. The highest essential oil yield was observed at the second harvest on10 April and 5 May of the first and second seasons, respectively. The essential oils at the different harvest times were characterized by containing monoterpenes with high amounts of β-pinene (24.1-54.6%) and sabinene (3.1-7.4%). The most abundant sesquiterpenes were chamazulene (10.1-26.7%) followed by geramacrene-D (1.3-10.3%) and β-caryophyllene (0.9-6.4%). Plants harvested on 21 February provided essential oil with relatively high concentration of chamazulene and germacrene-D. Chamazulene and germacrene-D decreased gradually at the later harvests, while β-pinene and limonene reached the maximum concentration in plants harvested on15 May. These results indicate that flowering heads yield and essential oil content and composition can be influenced by harvest time and climatic conditions which can be useful to producers and processors of Achillea millefolium.

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Section: Introductionmentioning

confidence: 99%

Yield and chemical composition of essential oil of Achillea millefolium L. as affected by harvest time

Aziz¹,

Badawy

Zheljazkov

et al. 2018

Egypt. J. Chem.

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“…One of the most important therapeutic effects of Yarrow plant is its anti-bacterial effect on a wide range of pathogens ( 19 ). The Yarrow fresh flowers have been used to treat respiratory problems ( 20 ). It was also employed as an anti-allergic ( 21 ), anti-congestion, and expectorant medicine ( 22 ).…”

Section: Introductionmentioning

confidence: 99%

A New mouthwash for Chemotherapy Induced Stomatitis

Miranzadeh¹,

Adib-Hajbaghery²,

Soleymanpoor³

et al. 2014

Nurs Midwifery Stud

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Background: Stomatitis is a disturbing side-effect of chemotherapy that disturbs patients and causes difficulties in patient’s drinking, eating and talking, and may results in infection and bleeding. Objectives: This study aimed to investigate the effect of Yarrow distillate in the treatment of chemotherapy-induced stomatitis. Patients and Methods: This randomized controlled trial study was conducted during 2013. The study population consisted of all cancer patients with chemotherapy-induced oral stomatitis referred to Shahid Beheshti Medical Center, Kashan, Iran. The data collection instrument had two-part; a demographic part and another part recording the severity of the stomatitis at the first, seventh, and 14th days of the intervention based on a WHO criteria checklist in 2005. In this study, 56 patients diagnosed with cancer were randomly assigned into control and experimental groups in similar blocks according to their stomatitis severity. The experimental group gargled 15 mL of a routine solution mixed with Yarrow distillate 4 times a day for 14 days while the control group gargled 15 mL of routine solution. The severity of stomatitis was assessed at the beginning of the intervention, and then after 7 and 14 days of the study. Data were analyzed using chi-square and Fisher exact test, Mann-Whitney U, Kruskal-Wallis, and Friedman tests using SPSS 11.5 software. Results: At first, the median score of stomatitis in the experimental group was 2.50 that significantly reduced to 1 and 0 in days 7 and 14 of the intervention, respectively ( P value < 0.001). However, in the control group, the median score of stomatitis was 2.50, which significantly increased to 3 in days 7 and 14 ( P value < 0.001). Conclusions: Yarrow distillate-contained solution reduced stomatitis severity more than the routine solution. Therefore, we suggest using it in patients with chemotherapy-induced stomatitis.

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“…This ayurvedic product may have better antioxidant activity endow with the ability to intercept the free radicals generated by cellular metabolism or exogenous sources, such as those resulting from the action of cyclophosphamide, thereby preventing their damage to lipids, amino acids, proteins, polyunsaturated fatty acid double bonds and DNA bases 18,19 . The aqueous extracts of AM and BF can act directly on compounds that induce mutations in DNA, chemically or enzymatically inactivating them, may inhibit the metabolic activation of promutagenic agents, or may scavenge reactive molecules, as explained 16,20 .…”

Section: -Amino Fluorinementioning

confidence: 99%