Antimicrobial Susceptibility Patterns of Enterobacteriaceae Isolated from Stool Samples at a Semi-urban Teaching Hospital

Elikwu, Charles John; Shobowale, Emmanuel Olushola; Nwadike, Victor; Tayo, Babatunde; Okangba, Chika Celen; Shonekan, Opeoluwa Akinyele; Omeonu, Azubuike Chidiebere; Bibitayo, Faluyi; Ile, Pearl; Adelodun, Adebola; Popoola, Adebusola; Mubele, Maxwell

doi:10.11648/j.ajbls.20150306.15

Cited by 2 publications

(2 citation statements)

References 34 publications

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“…This family is responsible for opportunistic infections, including pneumonia, septicemia, meningitis and urinary tract infections [5]. Most of these isolates are resistant to various antimicrobials, such as carbapenems, which are often believed to be the last line of antibiotic defense against resistant micro-organisms [6]. Although many of the modern antibacterial agents have been produced in recent decades, none of them has enhanced their efficacy against multidrug-resistant bacteria [7,8].…”

Section: Introductionmentioning

confidence: 99%

The synergistic effect of chitosan-alginate nanoparticle loaded with doxycycline antibiotic against multidrug resist enterobacteriaceae

alsaady

2020

eijs

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This study focused on the synthesis of chitosan-alginate (CH-ALg) nanoparticles by ionotropic gelation technique using sodium alginate and calcium chloride. The particle size of the synthesized nanoparticles was confirmed by atomic force microscope (AFM) and it was 61.9 nm. While the nature of functional groups present in chitosan nanoparticles was determined by FT-IR analysis. The antibacterial activity of chitosan-alginate was tested against multidrug resistance (MDR) gram- positive (Enterococcus faecalis) and gram-negative (Proteus mirabilis) bacteria. The results showed a significant effect against MDR isolates. The nanoparticles were loaded with the antibiotic doxycycline in order to improve the antibacterial activity and drug delivery efficiency. The synergistic effects of the biosynthesized chitosan-alginate and the loaded doxycycline at different concentrations against MDR bacteria were also investigated. The results showed that doxycycline-loaded nanoparticles have superior effectiveness compared to native doxycycline against gram negative and gram positive bacteria.

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Section: Introductionmentioning

confidence: 99%

The synergistic effect of chitosan-alginate nanoparticle loaded with doxycycline antibiotic against multidrug resist enterobacteriaceae

alsaady

2020

eijs

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“…However, unlike most similar bacteria, some members of the Enterobacteriaceae typically lack cytochrome C oxidase. Although there are exceptions, such as Plesiomonas Shiga [ 32 ]. This indicates that the denitrification intensity of MBR was higher than that of MSBR.…”

Section: Resultsmentioning

confidence: 99%

High-Density Microarray Analysis of Microbial Community Structures in Membrane Bioreactor at Short Sludge Retention Time

Duan

Song

et al. 2023

Membranes

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Membrane bioreactors (MBR) have become prevalent in wastewater treatment because of their high effluent quality and low sludge generation. Sludge retention time (SRT) is an important parameter in the operation of MBR, and it has a direct effect on the microbial community. In this study, microarrays were used to analyze the microbial communities of three different MBRs at short SRTs. The results showed that MBR at SRT 5 days (CS5) has the highest operational taxonomic units (OTUs) richness, but the lowest diversity and uniformity compared to SRT 3 days at continuous CS3 and the sequencing batch (SS3). Proteobacteria were the dominant phylum of three reactors. Bacteroidetes were the second dominant phylum in MBRs at the continuous model, instead of Actinobacteria at the sequencing model. At the class level, the dominant group of Proteobacteria exhibited a remarkable difference between the three MBRs. γ-Proteobacteria was the dominant group in CS5 and CS3, while α-Proteobacteria was the main group in SS3. The samples from the three MBRs had similar compositions of α-, β- and δ-Proteobacteria. However, γ-Proteobacteria showed different community compositions at the order level between the three MBRs. Enterobacteriales were the dominant group in CS5 and CS3, while Pseudomonadales were the dominant group in SS3. The bacterial community concentration of SRT 5 days was generally higher than that of the other two MBRs. The community composition of CS5 was significantly different from that of CS3 and SS3, and the phylogenetic relationships of the three MBRs were relatively different.

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Antimicrobial Susceptibility Patterns of Enterobacteriaceae Isolated from Stool Samples at a Semi-urban Teaching Hospital

Cited by 2 publications

References 34 publications

The synergistic effect of chitosan-alginate nanoparticle loaded with doxycycline antibiotic against multidrug resist enterobacteriaceae

The synergistic effect of chitosan-alginate nanoparticle loaded with doxycycline antibiotic against multidrug resist enterobacteriaceae

High-Density Microarray Analysis of Microbial Community Structures in Membrane Bioreactor at Short Sludge Retention Time

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